Protein: BMP4
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)

Gene: BMP4
Organism: Homo sapiens
Interactions: 130
UniProt ID: P12644

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001649 - osteoblast differentiation
GO:0001656 - metanephros development
GO:0001657 - ureteric bud development
GO:0001658 - branching involved in ureteric bud morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520110

BMR1A
Bone morphogenetic protein receptor type-1A

5

20

Small-scale

0.915

High

520153

BMPR2
Bone morphogenetic protein receptor type-2

4

20

Small-scale

0.890

High

265751

CRLF1
Cytokine receptor-like factor 1

1

1

High-throughput

0.691

High

122281

BMR1B
Bone morphogenetic protein receptor type-1B

1

20

Small-scale

0.647

High

520099

AVR2A
Activin receptor type-2A

1

20

Small-scale

0.647

High

520152

FSTL1
Follistatin-related protein 1

1

9

Small-scale

0.647

High

520161

RGMB
Repulsive guidance molecule B

1

6

Small-scale

0.647

High

520101

CALR
Calreticulin

2

6

High-throughput

0.628

High

520176

TWSG1
Twisted gastrulation protein homolog 1

2

3

Small-scale

0.619

High

520159

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

3

High-throughput

0.618

High

520175

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

0

High-throughput

0.602

High

520187

SUFU
Suppressor of fused homolog

2

0

High-throughput

0.602

High

500702

CLUS
Clusterin

2

0

High-throughput

0.585

High

520162

SOSD1
Sclerostin domain-containing protein 1

2

2

Small-scale

0.584

High

520182

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

2

1

High-throughput

0.574

High

238477

CST8
Cystatin-8

1

1

High-throughput

0.536

High

305209

NXPH2
Neurexophilin-2

1

1

High-throughput

0.536

High

423068

PROS
Vitamin K-dependent protein S

1

12

High-throughput

0.536

High

439261

MMP3
Stromelysin-1

1

6

High-throughput

0.536

High

448900

MMP10
Stromelysin-2

1

6

High-throughput

0.536

High

474690

CFC1
Cryptic protein

1

10

High-throughput

0.536

High

520090

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.536

High

520106

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

1

High-throughput

0.536

High

520144

IL5RA
Interleukin-5 receptor subunit alpha

1

3

High-throughput

0.536

High

520155

EP3A
Epididymal secretory protein E3-alpha

1

1

High-throughput

0.536

High

520157

ADIPO
Adiponectin

1

6

High-throughput

0.536

High

520169

CALR3
Calreticulin-3

1

6

High-throughput

0.536

High

520172

GPX7
Glutathione peroxidase 7

1

1

High-throughput

0.536

High

520177

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

520178

CBLN4
Cerebellin-4

1

5

High-throughput

0.536

High

520185

METRN
Meteorin

1

1

High-throughput

0.536

High

520186

FBX2
F-box only protein 2

1

5

High-throughput

0.536

High

520190

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.536

High

520192

LIPG
Endothelial lipase

1

2

High-throughput

0.536

High

121614

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

0

High-throughput

0.513

High

396313

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

441804

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.513

High

520118

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.513

High

520158

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.513

High

520163

IFNE
Interferon epsilon

1

0

High-throughput

0.513

High

520173

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.513

High

520181

IL20
Interleukin-20

1

0

High-throughput

0.513

High

520088

TDGF1
Protein Cripto

1

10

Small-scale

0.501

High

520142

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

16

Small-scale

0.501

High

520165

WFKN2
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

1

19

Small-scale

0.501

High

520170

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

1

13

Small-scale

0.501

High

235685

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

322125

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

488882

H14
Histone H1.4

1

2

High-throughput

0.479

High

501612

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

520089

BMP1
Bone morphogenetic protein 1

1

12

Small-scale

0.479

High

520091

H12
Histone H1.2

1

2

High-throughput

0.479

High

520094

EGR1
Early growth response protein 1

1

3

High-throughput

0.479

High

520096

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

520100

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

520104

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.479

High

520108

HNF1B
Hepatocyte nuclear factor 1-beta

1

3

High-throughput

0.479

High

520111

IF4A3
Eukaryotic initiation factor 4A-III

1

3

High-throughput

0.479

High

520120

FXR2
RNA-binding protein FXR2

1

2

High-throughput

0.479

High

520128

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.479

High

520133

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

520136

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

520139

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.479

High

520143

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.479

High

520150

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

2

High-throughput

0.479

High

520156

PCBP1
Poly(rC)-binding protein 1

1

4

High-throughput

0.479

High

417892

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

520095

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

520107

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

520114

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

520117

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.458

High

520126

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

520134

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

520138

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

520151

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.458

High

520168

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

0

High-throughput

0.458

High

520174

GTPB4
GTP-binding protein 4

1

0

High-throughput

0.458

High

520093

RL7
Large ribosomal subunit protein uL30

1

1

High-throughput

0.437

High

520097

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.437

High

520098

PTBP1
Polypyrimidine tract-binding protein 1

1

1

High-throughput

0.437

High

520102

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.437

High

520103

RL12
Large ribosomal subunit protein uL11

1

1

High-throughput

0.437

High

520105

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.437

High

520113

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.437

High

520121

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.437

High

520123

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.437

High

520127

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.437

High

520130

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

520131

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.437

High

520132

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

520145

EWS
RNA-binding protein EWS

1

8

High-throughput

0.437

High

520154

RBM39
RNA-binding protein 39

1

2

High-throughput

0.437

High

520164

DDX54
ATP-dependent RNA helicase DDX54

1

4

High-throughput

0.437

High

520171

SRPK1
SRSF protein kinase 1

1

2

High-throughput

0.437

High

520179

DDX18
ATP-dependent RNA helicase DDX18

1

2

High-throughput

0.437

High

520183

NHSL3
NHS-like protein 3

1

1

High-throughput

0.437

High

520184

PUF60
Poly(U)-binding-splicing factor PUF60

1

2

High-throughput

0.437

High

520189

SRRM2
Serine/arginine repetitive matrix protein 2

1

1

High-throughput

0.437

High

49723

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.328

High

520180

DCA16
DDB1- and CUL4-associated factor 16

2

0

High-throughput

0.328

High

155719

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

520148

KIME
Mevalonate kinase

1

0

High-throughput

0.279

Low

313493

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

0

High-throughput

0.265

Low

199658

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.249

Low

400729

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.249

Low

453109

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.249

Low

508308

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.249

Low

516340

PABP1
Polyadenylate-binding protein 1

1

0

High-throughput

0.249

Low

520092

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.249

Low

520109

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.249

Low

520112

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

520115

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.249

Low

520116

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.249

Low

520119

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.249

Low

520122

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

520124

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.249

Low

520125

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.249

Low

520129

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.249

Low

520135

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

520137

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.249

Low

520140

RT15
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.249

Low

520141

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

520146

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.249

Low

520147

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.249

Low

520149

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.249

Low

520166

H1X
Histone H1.10

1

0

High-throughput

0.249

Low

520167

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.249

Low

520188

DIM1
Probable dimethyladenosine transferase

1

0

High-throughput

0.249

Low

520191

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.249

Low

520160

CL060
Uncharacterized protein C12orf60

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024