Protein: DGLB
Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta)

Gene: DGLB, DAGLB
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q8NCG7

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0004806 - triacylglycerol lipase activity
GO:0005654 - nucleoplasm
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1335563

IGSF8
Immunoglobulin superfamily member 8

4

0

High-throughput

0.846

High

1142506

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.770

High

1293867

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.765

High

1335580

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

1

High-throughput

0.705

High

1335584

PCDC2
Protocadherin alpha-C2

3

3

High-throughput

0.662

High

967326

TSN5
Tetraspanin-5

3

5

High-throughput

0.650

High

212449

SPIT2
Kunitz-type protease inhibitor 2

3

0

High-throughput

0.638

High

252615

TSN2
Tetraspanin-2

2

3

High-throughput

0.628

High

1228638

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

1

High-throughput

0.628

High

1335578

PCDGG
Protocadherin gamma-B4

2

4

High-throughput

0.628

High

1335583

PCDG5
Protocadherin gamma-A5

2

4

High-throughput

0.628

High

1335575

SLAF7
SLAM family member 7

1

1

High-throughput

0.618

High

771179

APJ
Apelin receptor

2

0

High-throughput

0.602

High

829906

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.602

High

1335558

TPC2
Two pore channel protein 2

2

0

High-throughput

0.602

High

1335576

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

2

0

High-throughput

0.602

High

1270273

BT2A1
Butyrophilin subfamily 2 member A1

1

0

High-throughput

0.586

High

1335562

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

2

0

High-throughput

0.580

High

252698

TSN3
Tetraspanin-3

1

3

High-throughput

0.536

High

351926

S1PR4
Sphingosine 1-phosphate receptor 4

1

5

High-throughput

0.536

High

1203732

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1317071

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

3

High-throughput

0.536

High

1335556

ACV1C
Activin receptor type-1C

1

1

High-throughput

0.536

High

1335569

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1335573

LPAR2
Lysophosphatidic acid receptor 2

1

4

High-throughput

0.536

High

1335581

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

1335582

PCDGL
Protocadherin gamma-C4

1

4

High-throughput

0.536

High

248488

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.513

High

376623

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

1092381

TSN31
Tetraspanin-31

1

0

High-throughput

0.513

High

1159211

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1254065

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.513

High

1335571

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.513

High

1335574

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.513

High

1335579

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

0

High-throughput

0.513

High

641965

CD9
CD9 antigen

1

3

High-throughput

0.484

High

517063

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

178337

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

564920

ICAM2
Intercellular adhesion molecule 2

1

0

High-throughput

0.458

High

1249029

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1335566

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.458

High

349491

TSN15
Tetraspanin-15

1

4

High-throughput

0.445

High

1335561

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.445

High

1335567

S1PR3
Sphingosine 1-phosphate receptor 3

1

3

High-throughput

0.445

High

1277317

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

248915

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

437737

HEPS
Serine protease hepsin

1

0

High-throughput

0.426

High

702810

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.426

High

1335557

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

1

0

High-throughput

0.426

High

1335568

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

0

High-throughput

0.426

High

1335560

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

1335572

SACA1
Sperm acrosome membrane-associated protein 1

3

0

High-throughput

0.347

High

1335570

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.328

High

1335577

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.282

High

49803

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

486590

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.279

Low

1286733

CLC14
C-type lectin domain family 14 member A

1

0

High-throughput

0.279

Low

1324826

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1335559

SFT2A
Vesicle transport protein SFT2A

1

0

High-throughput

0.279

Low

1335565

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.279

Low

578

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

1307416

KRA13
Keratin-associated protein 1-3

1

0

High-throughput

0.251

Low

242311

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

1254688

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1335564

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

47913

S12A8
Solute carrier family 12 member 8

1

0

High-throughput

0.232

Low

1239246

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low

1333409

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025