Protein: HEXB
Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]

Gene: HEXB
Organism: Homo sapiens
Interactions: 62
UniProt ID: P07686

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001669 - acrosomal vesicle
GO:0004563 - beta-N-acetylhexosaminidase activity
GO:0005576 - extracellular region
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420705

HEXA
Beta-hexosaminidase subunit alpha

3

1

Small-scale

0.866

High

336312

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.602

High

429515

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.580

High

429542

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

429511

HEXB
Beta-hexosaminidase subunit beta

1

1

Small-scale

0.575

High

429513

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

217421

AIRE
Autoimmune regulator

1

0

High-throughput

0.518

High

396308

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

429512

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

429514

CALX
Calnexin

1

0

High-throughput

0.513

High

429520

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

High-throughput

0.513

High

125095

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.493

High

305845

UBL3
Ubiquitin-like protein 3

1

0

High-throughput

0.493

High

429541

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.493

High

429555

FBX2
F-box only protein 2

1

2

High-throughput

0.489

High

429517

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

429526

CUL3
Cullin-3

1

1

High-throughput

0.479

High

429550

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

429552

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

275485

CAN15
Calpain-15

1

1

High-throughput

0.470

High

429533

UBQLN
Ubiquilin-like protein

1

3

High-throughput

0.470

High

429547

UBQL3
Ubiquilin-3

1

3

High-throughput

0.470

High

429554

UBQL2
Ubiquilin-2

1

3

High-throughput

0.470

High

337784

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

429516

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

429524

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

429532

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

429536

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

429539

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

110741

POTB2
POTE ankyrin domain family member B2

1

2

High-throughput

0.437

High

204939

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

429529

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

429549

FBX6
F-box only protein 6

1

2

High-throughput

0.437

High

429553

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

2052

POTEB
POTE ankyrin domain family member B

1

2

High-throughput

0.407

High

48857

POTB3
POTE ankyrin domain family member B3

1

2

High-throughput

0.407

High

429551

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

429518

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.279

Low

429544

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.279

Low

429545

TSNAX
Translin-associated protein X

1

0

High-throughput

0.279

Low

277889

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.268

Low

429519

XIAP
E3 ubiquitin-protein ligase XIAP

1

0

High-throughput

0.268

Low

429521

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.268

Low

429522

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.268

Low

429523

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.268

Low

429525

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

0

High-throughput

0.268

Low

429528

RWDD4
RWD domain-containing protein 4

1

0

High-throughput

0.268

Low

429530

Q7KZS0
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.268

Low

429531

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.268

Low

429534

KLH36
Kelch-like protein 36

1

0

High-throughput

0.268

Low

429537

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.268

Low

429538

LNX1
E3 ubiquitin-protein ligase LNX

1

0

High-throughput

0.268

Low

429540

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.268

Low

429543

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.268

Low

429546

NXF2
Nuclear RNA export factor 2

1

0

High-throughput

0.268

Low

429556

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.268

Low

429557

ASB3
Ankyrin repeat and SOCS box protein 3

1

0

High-throughput

0.268

Low

429527

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

429548

MT21D
Protein N-lysine methyltransferase METTL21D

1

0

High-throughput

0.249

Low

200475

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

429535

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024