Protein: TSSC4
U5 small nuclear ribonucleoprotein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)

Gene: TSSC4
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q9Y5U2

Gene Ontology (top 5):
GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005682 - U5 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1159363

PRP8
Pre-mRNA-processing-splicing factor 8

6

0

High-throughput

0.699

High

272322

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

4

3

High-throughput

0.694

High

300301

PRP6
Pre-mRNA-processing factor 6

4

2

High-throughput

0.694

High

1288412

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

2

High-throughput

0.694

High

1318170

CRNL1
Crooked neck-like protein 1

4

2

High-throughput

0.694

High

1336503

SYF1
Pre-mRNA-splicing factor SYF1

4

2

High-throughput

0.694

High

1064908

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

5

0

High-throughput

0.684

High

1377506

AAR2
Protein AAR2 homolog

5

0

High-throughput

0.684

High

1310837

WDR83
WD repeat domain-containing protein 83

3

3

High-throughput

0.667

High

230824

AQR
RNA helicase aquarius

4

0

High-throughput

0.664

High

313381

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

4

0

High-throughput

0.664

High

327726

ECD
Protein ecdysoneless homolog

4

0

High-throughput

0.664

High

1039974

SNW1
SNW domain-containing protein 1

4

0

High-throughput

0.664

High

1122743

EAPP
E2F-associated phosphoprotein

4

0

High-throughput

0.664

High

1303900

CDC5L
Cell division cycle 5-like protein

4

0

High-throughput

0.664

High

1310471

GPTC1
G patch domain-containing protein 1

4

0

High-throughput

0.664

High

1356971

ISY1
Pre-mRNA-splicing factor ISY1 homolog

4

0

High-throughput

0.664

High

131533

IMA4
Importin subunit alpha-4

2

1

High-throughput

0.640

High

327826

SYF2
Pre-mRNA-splicing factor SYF2

3

0

High-throughput

0.638

High

949668

TXN4A
Thioredoxin-like protein 4A

3

0

High-throughput

0.638

High

1024975

RED
Protein Red

3

0

High-throughput

0.638

High

1347103

RBM22
Pre-mRNA-splicing factor RBM22

3

0

High-throughput

0.638

High

236272

PRP17
Pre-mRNA-processing factor 17

4

3

High-throughput

0.633

High

1332155

DHX35
Probable ATP-dependent RNA helicase DHX35

4

2

High-throughput

0.633

High

912013

RUXF
Small nuclear ribonucleoprotein F

2

2

High-throughput

0.628

High

928051

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

1

High-throughput

0.628

High

912603

SMD2
Small nuclear ribonucleoprotein Sm D2

3

0

High-throughput

0.628

High

539208

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

1

High-throughput

0.611

High

912136

RUXG
Small nuclear ribonucleoprotein G

2

4

High-throughput

0.611

High

912768

SMD3
Small nuclear ribonucleoprotein Sm D3

2

3

High-throughput

0.611

High

451335

TPM1
Tropomyosin alpha-1 chain

3

1

High-throughput

0.609

High

1103286

C19L2
CWF19-like protein 2

3

1

High-throughput

0.609

High

1148624

C19L1
CWF19-like protein 1

3

1

High-throughput

0.609

High

539869

IDE
Insulin-degrading enzyme

2

0

High-throughput

0.602

High

911781

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

1335767

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.602

High

1357569

PPIE
Peptidyl-prolyl cis-trans isomerase E

2

0

High-throughput

0.602

High

278575

SPF27
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.585

High

782190

BUD31
Protein BUD31 homolog

2

0

High-throughput

0.585

High

1294821

RSRC1
Serine/Arginine-related protein 53

2

0

High-throughput

0.585

High

1313236

DDX23
Probable ATP-dependent RNA helicase DDX23

2

0

High-throughput

0.585

High

1348148

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

2

0

High-throughput

0.585

High

1353908

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.585

High

1377957

PAXB1
PAX3- and PAX7-binding protein 1

2

0

High-throughput

0.585

High

1021004

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.573

High

1023844

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.573

High

981798

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

1348408

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.543

High

551333

ITF2
Transcription factor 4

1

0

High-throughput

0.536

High

853766

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.536

High

1290112

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.523

High

1121915

Q53SE7
Germ cell-less homolog 1

1

1

High-throughput

0.515

High

124533

TULP2
Tubby-related protein 2

1

0

High-throughput

0.513

High

257434

CNOT3
CCR4-NOT transcription complex subunit 3

1

0

High-throughput

0.513

High

365119

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

638597

RBTN1
Rhombotin-1

1

0

High-throughput

0.513

High

796214

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

1062724

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1283616

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

1288183

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.513

High

1345572

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.513

High

1349490

CWC15
Spliceosome-associated protein CWC15 homolog

1

0

High-throughput

0.513

High

419089

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.489

High

1077992

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.486

High

1294560

GMCL1
Germ cell-less protein-like 1

1

1

High-throughput

0.481

High

396135

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

209503

PLRG1
Pleiotropic regulator 1

1

1

High-throughput

0.479

High

912408

SMD1
Small nuclear ribonucleoprotein Sm D1

1

3

High-throughput

0.479

High

1055528

DHX8
ATP-dependent RNA helicase DHX8

1

2

High-throughput

0.479

High

1268352

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

2

High-throughput

0.479

High

1355021

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1357333

PRP19
Pre-mRNA-processing factor 19

1

1

High-throughput

0.479

High

1376991

RUVB2
RuvB-like 2

1

2

High-throughput

0.479

High

1377053

RUVB1
RuvB-like 1

1

2

High-throughput

0.479

High

1377524

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

3

High-throughput

0.479

High

229194

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

245140

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

296188

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.458

High

312986

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

348370

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

375164

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

875775

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

961343

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1239293

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1287609

S7A6O
Probable RNA polymerase II nuclear localization protein SLC7A6OS

1

0

High-throughput

0.458

High

1332830

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1336160

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.458

High

1378116

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.458

High

68472

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

4

High-throughput

0.445

High

607196

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.438

High

1147009

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

56780

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

1355581

ZNHI2
Zinc finger HIT domain-containing protein 2

4

0

High-throughput

0.362

High

1260040

CCD12
Coiled-coil domain-containing protein 12

3

0

High-throughput

0.347

High

1310239

LZTS2
Leucine zipper putative tumor suppressor 2

3

0

High-throughput

0.347

High

702818

CADH5
Cadherin-5

2

0

High-throughput

0.328

High

1244908

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1153071

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

2

0

High-throughput

0.318

High

1287550

AP2M1
AP-2 complex subunit mu

2

0

High-throughput

0.318

High

1353873

NCDN
Neurochondrin

2

0

High-throughput

0.318

High

995336

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.299

High

1251567

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.299

High

1045575

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.282

High

1102675

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1150195

ATLA3
Atlastin-3

1

0

High-throughput

0.279

Low

1159589

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.279

Low

1252919

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

281967

WFS1
Wolframin

1

0

High-throughput

0.268

Low

660775

GRN
Progranulin

1

0

High-throughput

0.268

Low

1201814

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024