Protein: MED20
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (Protein trf-proximal) (dMED20) (dTrap26) (dTrfp)

Gene: MED20
Organism: Drosophila melanogaster
Interactions: 52
UniProt ID: P91641

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045893 - positive regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1019312

MED18
Mediator of RNA polymerase II transcription subunit 18

5

1

High-throughput

0.912

High

1019294

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.737

High

1019276

MED6
Mediator of RNA polymerase II transcription subunit 6

3

1

Small-scale

0.664

High

1019291

MED17
Mediator of RNA polymerase II transcription subunit 17

3

1

Small-scale

0.651

High

1019302

MED11
Mediator of RNA polymerase II transcription subunit 11

3

1

Small-scale

0.633

High

1019306

MED30
Mediator of RNA polymerase II transcription subunit 30

3

2

Small-scale

0.633

High

1019271

MED29
Mediator of RNA polymerase II transcription subunit 29

2

1

High-throughput

0.571

High

1019273

MED31
Mediator of RNA polymerase II transcription subunit 31

2

1

High-throughput

0.571

High

1019281

EBI
F-box-like/WD repeat-containing protein ebi

2

1

High-throughput

0.571

High

1019284

MED10
Mediator of RNA polymerase II transcription subunit 10

2

1

High-throughput

0.571

High

1019285

MED7
Mediator of RNA polymerase II transcription subunit 7

2

1

High-throughput

0.571

High

1019292

Q9VF03
Brahma associated protein 155 kDa

2

2

High-throughput

0.571

High

1019298

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.571

High

1019299

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

1

High-throughput

0.571

High

1019300

CDK8
Cyclin-dependent kinase 8

2

3

High-throughput

0.571

High

1019303

BAP60
Brahma-associated protein of 60 kDa

2

1

High-throughput

0.571

High

1019307

MED14
Mediator of RNA polymerase II transcription subunit 14

2

1

High-throughput

0.571

High

1019310

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.571

High

1019313

MED15
Mediator of RNA polymerase II transcription subunit 15

2

1

High-throughput

0.571

High

900614

DSH
Segment polarity protein dishevelled

2

0

High-throughput

0.547

High

1019270

Q7JQT8
LD41464p

2

0

High-throughput

0.547

High

1019293

Q9VL29
GEO11246p1

2

0

High-throughput

0.547

High

1019275

ENC
Protein encore

2

1

High-throughput

0.521

High

56979

A1ZAK9
P-element somatic inhibitor, isoform A

1

3

High-throughput

0.479

High

1019287

MED22
Mediator of RNA polymerase II transcription subunit 22

1

1

Small-scale

0.479

High

1019288

MED28
Mediator of RNA polymerase II transcription subunit 28

1

1

Small-scale

0.479

High

1019296

Q9VR42
Serine/threonine-protein kinase RIO3

1

1

High-throughput

0.479

High

56930

A1ZAK7
LD35640p

1

3

High-throughput

0.445

High

58462

MED8
Mediator of RNA polymerase II transcription subunit 8

1

2

High-throughput

0.445

High

1019272

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.445

High

1019283

Q9BIW6
Brahma-associated protein 111kD

1

1

High-throughput

0.445

High

1019289

MED25
Mediator of RNA polymerase II transcription subunit 25

1

1

High-throughput

0.445

High

1019295

MED1
Mediator of RNA polymerase II transcription subunit 1

1

2

High-throughput

0.445

High

1019309

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.445

High

1019311

Q9W3G1
Uncharacterized protein, isoform A

1

1

High-throughput

0.445

High

86071

B9A0N7
BTB domain-containing protein

1

1

High-throughput

0.439

High

197443

O18353
CHIP

1

0

High-throughput

0.426

High

1019268

Q24090
GH08712p

1

0

High-throughput

0.426

High

1019274

OSA
Trithorax group protein osa

1

0

High-throughput

0.426

High

1019277

Q8SXP8
TAR DNA-binding protein 43

1

0

High-throughput

0.426

High

1019290

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

0

High-throughput

0.426

High

1019278

Q8T0F7
LD05823p

1

1

High-throughput

0.417

High

1019279

Q8T4A8
AT07769p

2

0

High-throughput

0.298

High

1019280

MESD
LDLR chaperone boca

2

0

High-throughput

0.298

High

1019286

LAR4
La-related protein Larp4B

2

0

High-throughput

0.298

High

1019301

Q9VUB7
PAX-interacting protein 1

2

0

High-throughput

0.298

High

1019308

Q9W115
FI14130p

1

0

High-throughput

0.265

Low

1019304

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

1019269

Q5BIL9
SD21168p

1

0

High-throughput

0.232

Low

1019282

Q960F7
SD03629p

1

0

High-throughput

0.232

Low

1019297

Q9VR43
AT09986p

1

0

High-throughput

0.232

Low

1019305

Q9W0L7
ubiquitinyl hydrolase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025