Protein: PTPA
Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B')

Gene: PTPA
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q15257

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930855

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

12

Small-scale

0.847

High

890966

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

2

10

High-throughput

0.789

High

915197

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

12

High-throughput

0.691

High

1069887

AMOT
Angiomotin

3

2

High-throughput

0.667

High

672131

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

3

3

Small-scale

0.653

High

175683

TRI18
E3 ubiquitin-protein ligase Midline-1

3

1

Small-scale

0.647

High

1069909

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

3

0

High-throughput

0.634

High

1069890

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

2

1

High-throughput

0.628

High

497057

TAU
Microtubule-associated protein tau

3

0

Small-scale

0.623

High

905914

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

High-throughput

0.618

High

681857

AKT1
RAC-alpha serine/threonine-protein kinase

2

1

Small-scale

0.602

High

206840

FOXO3
Forkhead box protein O3

2

1

Small-scale

0.595

High

1069895

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.580

High

1069906

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.580

High

1031530

ATM
Serine-protein kinase ATM

2

0

Small-scale

0.559

High

1069907

RGAP1
Rac GTPase-activating protein 1

1

0

Small-scale

0.554

High

986423

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

Small-scale

0.537

High

1069888

SGO1
Shugoshin 1

1

0

Small-scale

0.537

High

573272

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.536

High

770845

TCPZ
T-complex protein 1 subunit zeta

1

3

High-throughput

0.536

High

821224

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.536

High

826675

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.536

High

842879

TCPQ
T-complex protein 1 subunit theta

1

5

High-throughput

0.536

High

843208

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.536

High

943241

TCPB
T-complex protein 1 subunit beta

1

4

High-throughput

0.536

High

1069902

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.536

High

851774

CCNG1
Cyclin-G1

1

0

Small-scale

0.529

High

1069891

GASP3
G protein-coupled receptor associated sorting protein 3

1

0

Small-scale

0.529

High

1069897

NMD3A
Glutamate receptor ionotropic, NMDA 3A

1

0

Small-scale

0.529

High

408618

KPCB
Protein kinase C beta type

1

1

Small-scale

0.501

High

880732

HDAC4
Histone deacetylase 4

1

2

Small-scale

0.501

High

1069901

AURKB
Aurora kinase B

1

1

Small-scale

0.501

High

234656

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

High-throughput

0.493

High

1069889

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.493

High

154028

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.480

High

394745

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

555473

H2AX
Histone H2AX

1

0

Small-scale

0.480

High

624594

CCNE1
G1/S-specific cyclin-E1

1

0

Small-scale

0.480

High

835773

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.480

High

1038212

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.480

High

1069898

DTD1
D-aminoacyl-tRNA deacylase 1

1

0

Small-scale

0.480

High

1069903

TEP1
Telomerase protein component 1

1

0

Small-scale

0.480

High

1069904

ST4A1
Sulfotransferase 4A1

1

0

Small-scale

0.480

High

227512

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

435100

SP1
Transcription factor Sp1

1

1

Small-scale

0.479

High

655374

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.479

High

776693

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

777041

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

Small-scale

0.479

High

786354

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

805421

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

2

Small-scale

0.479

High

941658

IGBP1
Immunoglobulin-binding protein 1

1

2

Small-scale

0.479

High

970919

SP3
Transcription factor Sp3

1

1

Small-scale

0.479

High

1057263

SMC1A
Structural maintenance of chromosomes protein 1A

1

1

Small-scale

0.479

High

1069892

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1069911

STK26
Serine/threonine-protein kinase 26

1

1

High-throughput

0.479

High

1069912

HDAC6
Histone deacetylase 6

1

2

Small-scale

0.479

High

1069913

INT6
Integrator complex subunit 6

1

1

Small-scale

0.479

High

57679

A2BDD9
AMOT protein

1

2

High-throughput

0.470

High

244470

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

305176

UBE4B
Ubiquitin conjugation factor E4 B

1

0

Small-scale

0.458

High

338457

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

369647

ESR1
Estrogen receptor

1

0

High-throughput

0.458

High

418301

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

489424

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.458

High

667686

NOS3
Nitric oxide synthase 3

1

0

Small-scale

0.458

High

685964

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.458

High

717098

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

724840

MYH9
Myosin-9

1

0

High-throughput

0.458

High

805351

IEX1
Radiation-inducible immediate-early gene IEX-1

1

0

Small-scale

0.458

High

833883

CLK2
Dual specificity protein kinase CLK2

1

0

Small-scale

0.458

High

847808

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

890673

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

959218

S25A3
Solute carrier family 25 member 3

1

0

High-throughput

0.458

High

962789

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

963821

SET
Protein SET

1

0

Small-scale

0.458

High

974829

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

1056027

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1069884

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

Small-scale

0.458

High

1069885

MK14
Mitogen-activated protein kinase 14

1

0

Small-scale

0.458

High

1069886

F110C
Protein FAM110C

1

0

Small-scale

0.458

High

1069893

TBA1A
Tubulin alpha-1A chain

1

0

Small-scale

0.458

High

1069894

MARK2
Serine/threonine-protein kinase MARK2

1

0

Small-scale

0.458

High

1069896

MYCD
Myocardin

1

0

High-throughput

0.458

High

1069900

MYL11
Myosin regulatory light chain 11

1

0

High-throughput

0.458

High

850056

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

Small-scale

0.445

High

1069905

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.438

High

943838

RAE1L
mRNA export factor RAE1

1

0

Small-scale

0.426

High

483689

CT456
Cancer/testis antigen family 45 member A6

1

1

High-throughput

0.407

High

1069910

SPG21
Maspardin

2

0

High-throughput

0.316

High

1069908

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.292

High

532873

TF
Tissue factor

1

0

Small-scale

0.261

Low

1069899

KISSR
KiSS-1 receptor

1

0

Small-scale

0.261

Low

329736

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

396522

CP17A
Steroid 17-alpha-hydroxylase/17,20 lyase

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024