Protein: PP2BA
Protein phosphatase 3 catalytic subunit alpha (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin A alpha) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha) (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform)

Gene: PP2BA, PPP3CA
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q08209

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0001975 - response to amphetamine
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926731

CANB1
Calcineurin subunit B type 1

16

20

Small-scale

0.987

High

994104

CANB2
Calcineurin subunit B type 2

2

20

High-throughput

0.793

High

865104

RCAN1
Calcipressin-1

6

11

Small-scale

0.738

High

317957

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

4

10

Small-scale

0.708

High

994080

RCAN2
Calcipressin-2

4

11

Small-scale

0.696

High

623537

AKAP5
A-kinase anchor protein 5

4

1

Small-scale

0.696

High

557541

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

14

High-throughput

0.691

High

505812

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

3

5

High-throughput

0.667

High

994083

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

3

11

High-throughput

0.667

High

994100

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

3

2

High-throughput

0.667

High

994121

RCAN3
Calcipressin-3

3

11

High-throughput

0.667

High

994124

SIK3
Serine/threonine-protein kinase SIK3

3

10

High-throughput

0.667

High

994094

TENS4
Tensin-4

3

8

High-throughput

0.665

High

994113

ARMT1
Damage-control phosphatase ARMT1

3

1

High-throughput

0.665

High

994102

CP074
Uncharacterized protein C16orf74

5

1

High-throughput

0.660

High

835697

GSK3B
Glycogen synthase kinase-3 beta

3

18

High-throughput

0.656

High

994090

TRI72
Tripartite motif-containing protein 72

3

1

Small-scale

0.653

High

174827

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.647

High

924515

GRB2
Growth factor receptor-bound protein 2

3

11

High-throughput

0.646

High

401895

JUN
Transcription factor Jun

2

7

Small-scale

0.629

High

994097

PAR3L
Partitioning defective 3 homolog B

1

20

High-throughput

0.618

High

994081

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

Small-scale

0.618

High

994125

CSEN
Calsenilin

1

0

Small-scale

0.614

High

835347

GSK3A
Glycogen synthase kinase-3 alpha

2

18

High-throughput

0.611

High

841547

RASF2
Ras association domain-containing protein 2

2

1

High-throughput

0.611

High

655529

IP3KB
Inositol-trisphosphate 3-kinase B

2

3

High-throughput

0.606

High

827741

AMPH
Amphiphysin

2

7

High-throughput

0.606

High

994077

U119A
Protein unc-119 homolog A

2

1

High-throughput

0.606

High

994118

ABI2
Abl interactor 2

2

15

High-throughput

0.606

High

994123

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

2

8

High-throughput

0.606

High

994117

NSMA2
Sphingomyelin phosphodiesterase 3

2

0

High-throughput

0.602

High

227269

PRKN
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.584

High

489405

BCL2
Apoptosis regulator Bcl-2

2

13

Small-scale

0.584

High

483921

CALM1
Calmodulin-1

1

17

High-throughput

0.575

High

483996

CALM2
Calmodulin-2

1

17

High-throughput

0.575

High

484113

CALM3
Calmodulin-3

1

17

High-throughput

0.575

High

59750

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

2

High-throughput

0.574

High

887028

DEF1
Neutrophil defensin 1

2

2

High-throughput

0.574

High

994093

T200A
Transmembrane protein 200A

2

2

High-throughput

0.574

High

584243

ELK1
ETS domain-containing protein Elk-1

2

1

High-throughput

0.571

High

994076

GRB10
Growth factor receptor-bound protein 10

2

17

High-throughput

0.571

High

994099

SH3K1
SH3 domain-containing kinase-binding protein 1

2

13

High-throughput

0.571

High

681221

SC6A4
Sodium-dependent serotonin transporter

1

2

Small-scale

0.561

High

529031

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

High-throughput

0.552

High

923653

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

Small-scale

0.546

High

607951

FGFR4
Fibroblast growth factor receptor 4

1

4

High-throughput

0.541

High

713791

RYK
Tyrosine-protein kinase RYK

1

9

High-throughput

0.541

High

994075

PTK7
Inactive tyrosine-protein kinase 7

1

4

High-throughput

0.541

High

742252

SYUA
Alpha-synuclein

1

0

Small-scale

0.537

High

994078

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

10

Small-scale

0.536

High

153117

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

9

High-throughput

0.536

High

414890

CDK1
Cyclin-dependent kinase 1

1

12

High-throughput

0.536

High

536515

IRF2
Interferon regulatory factor 2

1

1

High-throughput

0.536

High

933179

TBA1B
Tubulin alpha-1B chain

1

7

High-throughput

0.536

High

994088

LBH
Protein LBH

1

2

High-throughput

0.536

High

994098

PMEPA
Protein TMEPAI

1

2

High-throughput

0.536

High

994105

SPT33
Spermatogenesis-associated protein 33

1

2

High-throughput

0.536

High

893657

PSA6
Proteasome subunit alpha type-6

1

0

Small-scale

0.529

High

994079

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

994101

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.515

High

131143

ZN593
Zinc finger protein 593

1

0

High-throughput

0.513

High

994107

CND3
Condensin complex subunit 3

1

0

High-throughput

0.513

High

305171

UBE4B
Ubiquitin conjugation factor E4 B

1

1

Small-scale

0.501

High

475666

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

High-throughput

0.501

High

994082

LASP1
LIM and SH3 domain protein 1

1

3

Small-scale

0.501

High

994120

KLHL3
Kelch-like protein 3

1

1

Small-scale

0.501

High

994122

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.501

High

809105

UTRN
Utrophin

1

9

Small-scale

0.500

High

994089

LMTK1
Serine/threonine-protein kinase LMTK1

1

15

High-throughput

0.494

High

336476

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

472657

F163B
Protein FAM163B

1

2

High-throughput

0.489

High

994112

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

2

Small-scale

0.481

High

994119

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.481

High

994126

CABIN
Calcineurin-binding protein cabin-1

1

10

Small-scale

0.481

High

294752

RECQ4
ATP-dependent DNA helicase Q4

1

9

High-throughput

0.479

High

337448

ABL1
Tyrosine-protein kinase ABL1

1

5

High-throughput

0.479

High

377274

GCR
Glucocorticoid receptor

1

14

High-throughput

0.479

High

386607

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

455360

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

552571

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

651039

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

659707

RXRB
Retinoic acid receptor RXR-beta

1

10

High-throughput

0.479

High

681810

AKT1
RAC-alpha serine/threonine-protein kinase

1

6

Small-scale

0.479

High

720307

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

779298

CCNF
Cyclin-F

1

13

High-throughput

0.479

High

870771

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

6

Small-scale

0.479

High

874865

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

890629

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

Small-scale

0.479

High

994071

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

3

Small-scale

0.479

High

994072

TRAF3
TNF receptor-associated factor 3

1

9

Small-scale

0.479

High

994073

TADBP
TAR DNA-binding protein 43

1

10

Small-scale

0.479

High

994074

MK07
Mitogen-activated protein kinase 7

1

7

Small-scale

0.479

High

994084

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

994085

CCDC6
Coiled-coil domain-containing protein 6

1

18

High-throughput

0.479

High

994086

ANR55
Ankyrin repeat domain-containing protein 55

1

4

High-throughput

0.479

High

994087

CRTC2
CREB-regulated transcription coactivator 2

1

12

Small-scale

0.479

High

994091

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

994092

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

14

Small-scale

0.479

High

994096

CEP76
Centrosomal protein of 76 kDa

1

1

High-throughput

0.479

High

994109

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

994110

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

994111

ECT2
Protein ECT2

1

9

High-throughput

0.479

High

994114

MYOZ1
Myozenin-1

1

1

Small-scale

0.479

High

994115

MYOZ2
Myozenin-2

1

1

Small-scale

0.479

High

994095

ARL14
ADP-ribosylation factor-like protein 14

1

0

High-throughput

0.458

High

994108

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

601905

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

8

High-throughput

0.457

High

994116

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

378034

PRIO
Major prion protein

1

1

High-throughput

0.445

High

496917

TAU
Microtubule-associated protein tau

1

19

High-throughput

0.445

High

100704

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

795738

MAGA3
Melanoma-associated antigen 3

1

3

Small-scale

0.437

High

994106

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

831261

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

994103

F167A
Protein FAM167A

2

0

High-throughput

0.316

High

898857

SMS
Somatostatin

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024