Protein: CDS2
Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2)

Gene: CDS2
Organism: Homo sapiens
Interactions: 129
UniProt ID: O95674

Gene Ontology (top 5):
GO:0004605 - phosphatidate cytidylyltransferase activity
GO:0005743 - mitochondrial inner membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006655 - phosphatidylglycerol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341461

CDS1
Phosphatidate cytidylyltransferase 1

3

1

High-throughput

0.861

High

341383

TSN12
Tetraspanin-12

2

3

High-throughput

0.606

High

341462

HMR1
Major histocompatibility complex class I-related protein 1

2

1

High-throughput

0.606

High

341440

TM139
Transmembrane protein 139

2

0

High-throughput

0.580

High

341454

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

341455

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

341479

RN122
RING finger protein 122

2

0

High-throughput

0.580

High

341482

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.580

High

341491

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

341492

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

341394

FGFR3
Fibroblast growth factor receptor 3

2

0

High-throughput

0.575

High

341428

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

341452

GP152
Probable G-protein coupled receptor 152

2

5

High-throughput

0.553

High

230232

CREB3
Cyclic AMP-responsive element-binding protein 3

2

0

High-throughput

0.551

High

341439

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

4

High-throughput

0.549

High

129944

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.536

High

182446

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.536

High

341404

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

High-throughput

0.536

High

341409

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

1

High-throughput

0.536

High

341457

AQP3
Aquaporin-3

1

1

High-throughput

0.536

High

341466

VSIG2
V-set and immunoglobulin domain-containing protein 2

1

3

High-throughput

0.536

High

341475

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.536

High

341490

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

4

High-throughput

0.536

High

341494

SRPRB
Signal recognition particle receptor subunit beta

1

1

High-throughput

0.536

High

341421

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

1

High-throughput

0.515

High

49724

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

341407

EMD
Emerin

1

0

High-throughput

0.513

High

341408

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.513

High

341413

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

341414

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

341422

SLMAP
Sarcolemmal membrane-associated protein

1

0

High-throughput

0.513

High

341425

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

341434

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

341444

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

341446

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

341450

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

341451

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

341464

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

341469

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

341472

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.513

High

341478

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

341485

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

341488

CLC2D
C-type lectin domain family 2 member D

1

0

High-throughput

0.513

High

341463

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.494

High

341473

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.494

High

280446

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

341385

RASH
GTPase HRas

1

0

High-throughput

0.493

High

341392

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

341403

HD
Huntingtin

1

0

High-throughput

0.493

High

341412

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

341460

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

341489

UBQL1
Ubiquilin-1

1

0

High-throughput

0.493

High

165880

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

341384

S1PR4
Sphingosine 1-phosphate receptor 4

1

2

High-throughput

0.489

High

341399

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

341437

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

1

High-throughput

0.489

High

341453

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

1

High-throughput

0.489

High

341474

YIPF3
Protein YIPF3

1

1

High-throughput

0.489

High

341484

GP173
Probable G-protein coupled receptor 173

1

1

High-throughput

0.489

High

341486

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.489

High

341495

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

341388

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

341483

SAR1A
Small COPII coat GTPase SAR1A

1

0

High-throughput

0.460

High

341497

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.460

High

284367

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

Small-scale

0.458

High

341389

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

341417

CLN3
Battenin

1

0

Small-scale

0.458

High

341427

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

341445

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

341493

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

303208

S22A5
Organic cation/carnitine transporter 2

1

4

High-throughput

0.445

High

341386

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

341393

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

341405

S6A12
Sodium- and chloride-dependent betaine transporter

1

3

High-throughput

0.445

High

341423

S39AE
Metal cation symporter ZIP14

1

3

High-throughput

0.445

High

341443

S35F2
Solute carrier family 35 member F2

1

3

High-throughput

0.445

High

341458

S39A7
Zinc transporter SLC39A7

1

3

High-throughput

0.445

High

292986

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

341416

TRAF3
TNF receptor-associated factor 3

1

1

Small-scale

0.437

High

341433

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

341459

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

341391

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

341441

S22A9
Organic anion transporter 7

1

4

High-throughput

0.407

High

341449

S35G2
Solute carrier family 35 member G2

1

3

High-throughput

0.407

High

341456

CTR3
Cationic amino acid transporter 3

1

1

High-throughput

0.407

High

341481

S39A2
Zinc transporter ZIP2

1

3

High-throughput

0.407

High

71832

LEUTX
Paired-like homeodomain transcription factor LEUTX

2

0

High-throughput

0.316

High

341397

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.316

High

341419

I10R1
Interleukin-10 receptor subunit alpha

2

0

High-throughput

0.316

High

341436

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

341448

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

341465

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

341467

JSPR1
Junctional sarcoplasmic reticulum protein 1

2

0

High-throughput

0.316

High

341476

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

341426

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

Small-scale

0.305

High

341470

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.282

High

190541

COPT2
Protein SLC31A2

1

0

High-throughput

0.279

Low

260821

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

341400

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

341401

GPV
Platelet glycoprotein V

1

0

High-throughput

0.279

Low

341415

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

0

High-throughput

0.279

Low

341429

INT3
Integrator complex subunit 3

1

0

High-throughput

0.279

Low

341432

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

341442

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

341468

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.279

Low

109354

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

341390

GELS
Gelsolin

1

0

High-throughput

0.268

Low

341396

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

341398

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.268

Low

341410

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

341435

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

341438

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

341480

MYG1
MYG1 exonuclease

1

0

High-throughput

0.268

Low

341496

Q9Y649
GW128

1

0

High-throughput

0.268

Low

341387

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

341418

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.251

Low

105029

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

341395

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

341402

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

341411

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.249

Low

341430

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

341431

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

341471

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

341477

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

341406

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.232

Low

341420

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.232

Low

341424

S15A2
Solute carrier family 15 member 2

1

0

High-throughput

0.232

Low

341447

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.232

Low

341487

S23A1
Solute carrier family 23 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025