Protein: TPPC8
Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)

Gene: TPPC8, TRAPPC8
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q9Y2L5

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007030 - Golgi organization
GO:0030008 - TRAPP complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1358533

TPC12
Trafficking protein particle complex subunit 12

4

1

Small-scale

0.695

High

515746

TPC2B
Trafficking protein particle complex subunit 2B

4

3

Small-scale

0.676

High

1490816

TPPC1
Trafficking protein particle complex subunit 1

3

1

High-throughput

0.675

High

1461404

TPC2L
Trafficking protein particle complex subunit 2-like protein

3

3

Small-scale

0.662

High

1307862

TPPC5
Trafficking protein particle complex subunit 5

2

1

High-throughput

0.628

High

1276050

TPC11
Trafficking protein particle complex subunit 11

2

1

Small-scale

0.614

High

1286682

TPC6B
Trafficking protein particle complex subunit 6B

2

1

Small-scale

0.614

High

712309

TKT
Transketolase

2

0

High-throughput

0.602

High

1340753

TPC2
Two pore channel protein 2

2

0

High-throughput

0.602

High

1454707

TBC14
TBC1 domain family member 14

2

0

High-throughput

0.602

High

221768

TPPC3
Trafficking protein particle complex subunit 3

2

1

Small-scale

0.601

High

1490815

TPPC8
Trafficking protein particle complex subunit 8

1

0

Small-scale

0.589

High

1400449

TPPC9
Trafficking protein particle complex subunit 9

2

0

Small-scale

0.552

High

376122

RASK
GTPase KRas

1

1

High-throughput

0.536

High

783181

ARL3
ADP-ribosylation factor-like protein 3

1

1

High-throughput

0.536

High

1295427

RAB43
Ras-related protein Rab-43

1

1

High-throughput

0.536

High

730380

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.513

High

766032

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

952674

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.513

High

958387

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1116155

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

1387454

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.513

High

1429549

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.513

High

1450645

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.513

High

1454587

KLH14
Kelch-like protein 14

1

0

High-throughput

0.513

High

1462719

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.513

High

63875

TPC13
Trafficking protein particle complex subunit 13

1

0

Small-scale

0.493

High

1212068

TPC3L
Trafficking protein particle complex subunit 3-like protein

1

1

Small-scale

0.481

High

1490634

TPPC4
Trafficking protein particle complex subunit 4

1

1

Small-scale

0.481

High

180111

BET1
BET1 homolog

1

1

High-throughput

0.479

High

226273

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

540768

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

541771

FGFR1
Fibroblast growth factor receptor 1

1

3

High-throughput

0.479

High

604281

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

641287

FGFR2
Fibroblast growth factor receptor 2

1

3

High-throughput

0.479

High

902152

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

874073

TPC10
Trafficking protein particle complex subunit 10

1

0

Small-scale

0.460

High

1406809

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.460

High

1450414

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

0

Small-scale

0.460

High

243336

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

660759

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.458

High

976681

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1106757

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1115161

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1133060

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1256172

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1401735

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.458

High

1416070

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

High-throughput

0.458

High

1433012

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

1434275

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1459370

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1460314

XPO7
Exportin-7

1

0

High-throughput

0.458

High

515664

TPC2A
Trafficking protein particle complex subunit 2

1

3

High-throughput

0.445

High

412845

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

560562

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

562501

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.437

High

631032

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

648749

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.437

High

1031609

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1323052

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1462782

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

530621

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1065503

SSRP1
FACT complex subunit SSRP1

2

0

High-throughput

0.328

High

1280176

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.279

Low

1387352

OTUB2
Ubiquitin thioesterase OTUB2

1

0

High-throughput

0.279

Low

1135515

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

1257178

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.251

Low

140038

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

189941

STX7
Syntaxin-7

1

0

High-throughput

0.249

Low

218988

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

488894

FURIN
Furin

1

0

High-throughput

0.249

Low

769558

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1233593

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1276995

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025