Protein: IREB2
Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2)

Gene: IREB2
Organism: Homo sapiens
Interactions: 47
UniProt ID: P48200

Gene Ontology (top 5):
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0003723 - RNA binding
GO:0003994 - aconitate hydratase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

870978

FBXL5
F-box/LRR-repeat protein 5

6

1

Small-scale

0.741

High

870975

CIA2A
Cytosolic iron-sulfur assembly component 2A

3

2

Small-scale

0.656

High

848006

AL3B1
Aldehyde dehydrogenase family 3 member B1

2

5

High-throughput

0.628

High

870955

ELAV2
ELAV-like protein 2

2

1

High-throughput

0.628

High

870963

CMKMT
Calmodulin-lysine N-methyltransferase

2

1

High-throughput

0.611

High

870971

CCNL2
Cyclin-L2

3

3

High-throughput

0.609

High

870972

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

0

Small-scale

0.605

High

870977

ARL15
ADP-ribosylation factor-like protein 15

3

2

High-throughput

0.604

High

302776

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

1

Small-scale

0.584

High

870953

YBOX1
Y-box-binding protein 1

1

2

Small-scale

0.561

High

870960

OTUD3
OTU domain-containing protein 3

1

0

Small-scale

0.537

High

870957

SRSF7
Serine/arginine-rich splicing factor 7

1

2

High-throughput

0.536

High

870964

THOC4
THO complex subunit 4

1

1

High-throughput

0.536

High

870965

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

2

High-throughput

0.536

High

870966

PABP5
Polyadenylate-binding protein 5

1

1

High-throughput

0.536

High

870973

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

1

High-throughput

0.536

High

870976

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.536

High

390488

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.515

High

870969

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

1

High-throughput

0.515

High

226963

ENSA
Alpha-endosulfine

1

0

High-throughput

0.513

High

303115

RGS20
Regulator of G-protein signaling 20

1

0

High-throughput

0.513

High

870970

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

0

High-throughput

0.513

High

421698

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

595347

H15
Histone H1.5

1

0

High-throughput

0.493

High

400464

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

631624

RAB6A
Ras-related protein Rab-6A

1

1

High-throughput

0.479

High

681290

PSA3
Proteasome subunit alpha type-3

1

1

Small-scale

0.479

High

830321

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

870954

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.479

High

870974

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

Small-scale

0.479

High

870979

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.479

High

870981

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

2

High-throughput

0.479

High

162922

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.460

High

275262

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

Small-scale

0.458

High

352360

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

822523

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

870968

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.458

High

870961

Q6ICH2
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.437

High

870980

BSN
Protein bassoon

1

2

High-throughput

0.437

High

73377

B2CML4
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.407

High

870952

INSL3
Insulin-like 3

3

0

High-throughput

0.347

High

870962

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.282

High

870956

ZN174
Zinc finger protein 174

1

0

High-throughput

0.279

Low

870959

H1BP3
HCLS1-binding protein 3

1

0

High-throughput

0.279

Low

870967

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

870958

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.269

Low

517304

GAGE1
G antigen 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025