Protein: PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17)

Gene: PDE6D
Organism: Homo sapiens
Interactions: 59
UniProt ID: O43924

Gene Ontology (top 5):
GO:0005095 - GTPase inhibitor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

231376

ARL2
ADP-ribosylation factor-like protein 2

10

4

Small-scale

0.981

High

231377

ARL3
ADP-ribosylation factor-like protein 3

8

4

Small-scale

0.970

High

231392

ARL16
ADP-ribosylation factor-like protein 16

4

3

High-throughput

0.904

High

231409

ARL15
ADP-ribosylation factor-like protein 15

3

3

High-throughput

0.770

High

231402

RPGR
X-linked retinitis pigmentosa GTPase regulator

6

0

Small-scale

0.711

High

231394

RHEB
GTP-binding protein Rheb

3

3

Small-scale

0.665

High

231381

RAB28
Ras-related protein Rab-28

3

3

Small-scale

0.662

High

231387

RAP1A
Ras-related protein Rap-1A

3

3

Small-scale

0.645

High

231407

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

3

0

Small-scale

0.634

High

231361

RASH
GTPase HRas

2

3

Small-scale

0.595

High

231401

RND1
Rho-related GTP-binding protein Rho6

2

3

Small-scale

0.595

High

231362

RASK
GTPase KRas

2

3

Small-scale

0.595

High

231378

TALDO
Transaldolase

2

0

High-throughput

0.585

High

231393

CUL1
Cullin-1

2

0

Small-scale

0.585

High

231405

TB10A
TBC1 domain family member 10A

2

0

Small-scale

0.576

High

231410

FBX10
F-box only protein 10

2

0

Small-scale

0.576

High

231391

LMNB2
Lamin-B2

2

2

Small-scale

0.549

High

231383

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.541

High

231406

RAB18
Ras-related protein Rab-18

1

1

High-throughput

0.541

High

231357

A1AT
Alpha-1-antitrypsin

1

1

High-throughput

0.536

High

231366

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.536

High

231404

FXL20
F-box/LRR-repeat protein 20

1

1

High-throughput

0.536

High

231379

PI2R
Prostacyclin receptor

1

0

Small-scale

0.529

High

231380

RAB13
Ras-related protein Rab-13

1

0

Small-scale

0.529

High

181590

CETN3
Centrin-3

1

0

High-throughput

0.518

High

231382

RD23A
UV excision repair protein RAD23 homolog A

1

0

High-throughput

0.518

High

231354

SUN1
SUN domain-containing protein 1

1

0

High-throughput

0.513

High

231367

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

231371

ALBU
Albumin

1

0

High-throughput

0.513

High

231372

TRFE
Serotransferrin

1

0

High-throughput

0.513

High

231375

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.513

High

231390

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.513

High

231400

SYNE2
Nesprin-2

1

0

High-throughput

0.513

High

231403

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

231358

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.489

High

231359

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.489

High

231360

CO3
Complement C3

1

1

High-throughput

0.489

High

231368

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

1

High-throughput

0.489

High

231369

FIBG
Fibrinogen gamma chain

1

1

High-throughput

0.489

High

231374

LMNB1
Lamin-B1

1

2

High-throughput

0.489

High

231384

RAP2B
Ras-related protein Rap-2b

1

2

Small-scale

0.481

High

231385

RHOA
Transforming protein RhoA

1

2

Small-scale

0.481

High

231386

RHOB
Rho-related GTP-binding protein RhoB

1

2

Small-scale

0.481

High

231411

FBXL2
F-box/LRR-repeat protein 2

1

1

Small-scale

0.479

High

231389

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

231388

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

Small-scale

0.426

High

231363

IGKC
Immunoglobulin kappa constant

1

2

High-throughput

0.407

High

231364

IGHG1
Immunoglobulin heavy constant gamma 1

1

2

High-throughput

0.407

High

231365

IGHG2
Immunoglobulin heavy constant gamma 2

1

2

High-throughput

0.407

High

231398

F219A
Protein FAM219A

2

0

High-throughput

0.330

High

231396

OTP
Homeobox protein orthopedia

2

0

High-throughput

0.316

High

231355

UBL3
Ubiquitin-like protein 3

1

0

High-throughput

0.279

Low

231356

HPT
Haptoglobin

1

0

High-throughput

0.279

Low

231370

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.279

Low

231373

HEMO
Hemopexin

1

0

High-throughput

0.279

Low

231395

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

231397

I2BP1
Interferon regulatory factor 2-binding protein 1

1

0

High-throughput

0.279

Low

231399

NIM1
Serine/threonine-protein kinase NIM1

1

0

High-throughput

0.279

Low

231408

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025