Protein: TTF2
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)

Gene: TTF2
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9UNY4

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1351542

HAVR2
Hepatitis A virus cellular receptor 2

3

0

High-throughput

0.715

High

1292826

SKAP1
Src kinase-associated phosphoprotein 1

3

12

High-throughput

0.667

High

1356782

HDAC7
Histone deacetylase 7

3

20

High-throughput

0.667

High

1429518

CLPB
Mitochondrial disaggregase

3

7

Small-scale

0.664

High

1086195

CETN1
Centrin-1

3

2

High-throughput

0.662

High

1138173

TNIP1
TNFAIP3-interacting protein 1

3

20

Small-scale

0.661

High

1404511

CDC5L
Cell division cycle 5-like protein

2

20

Small-scale

0.644

High

828472

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.638

High

851445

PRS6B
26S proteasome regulatory subunit 6B

2

7

High-throughput

0.628

High

1428611

DNAI2
Dynein axonemal intermediate chain 2

1

20

High-throughput

0.618

High

953183

ACTB
Actin, cytoplasmic 1

1

19

High-throughput

0.618

High

980545

H4
Histone H4

1

18

High-throughput

0.618

High

173554

XPO1
Exportin-1

2

9

High-throughput

0.611

High

587257

ITF2
Transcription factor 4

2

6

High-throughput

0.606

High

1328855

COMD1
COMM domain-containing protein 1

2

0

High-throughput

0.602

High

1357022

PDC6I
Programmed cell death 6-interacting protein

2

17

Small-scale

0.600

High

1411858

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

0

High-throughput

0.585

High

1108287

SQSTM
Sequestosome-1

2

3

High-throughput

0.584

High

1123875

DCTN1
Dynactin subunit 1

2

8

High-throughput

0.584

High

1462417

NINL
Ninein-like protein

2

14

High-throughput

0.584

High

1461034

GMEB2
Glucocorticoid modulatory element-binding protein 2

2

0

High-throughput

0.580

High

1458957

TRI10
Tripartite motif-containing protein 10

1

2

High-throughput

0.575

High

1461903

FZR1
Fizzy-related protein homolog

1

17

High-throughput

0.561

High

1309354

CDKL3
Cyclin-dependent kinase-like 3

1

6

High-throughput

0.541

High

1333256

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

4

High-throughput

0.541

High

158517

RFXK
DNA-binding protein RFXANK

1

7

High-throughput

0.536

High

186865

FOXN1
Forkhead box protein N1

1

20

High-throughput

0.536

High

259177

DNJA2
DnaJ homolog subfamily A member 2

1

8

High-throughput

0.536

High

296847

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.536

High

334264

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

6

High-throughput

0.536

High

347415

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

407730

S100B
Protein S100-B

1

13

High-throughput

0.536

High

449631

KLK1
Kallikrein-1

1

9

High-throughput

0.536

High

457772

TBB5
Tubulin beta chain

1

6

High-throughput

0.536

High

549360

SRF
Serum response factor

1

11

High-throughput

0.536

High

593246

CREB1
Cyclic AMP-responsive element-binding protein 1

1

5

High-throughput

0.536

High

783682

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

5

High-throughput

0.536

High

848747

MAGA9
Melanoma-associated antigen 9

1

10

High-throughput

0.536

High

945732

FOXL2
Forkhead box protein L2

1

20

High-throughput

0.536

High

1041806

PPARD
Peroxisome proliferator-activated receptor delta

1

20

High-throughput

0.536

High

1144219

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

1235571

IFIX
Pyrin and HIN domain-containing protein 1

1

10

High-throughput

0.536

High

1361067

ASB13
Ankyrin repeat and SOCS box protein 13

1

7

High-throughput

0.536

High

1383890

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

1387294

HDA11
Histone deacetylase 11

1

20

High-throughput

0.536

High

1402739

TCPQM
T-complex protein 1 subunit theta-like 2

1

9

High-throughput

0.536

High

1420260

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

1432498

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.536

High

1460139

NRBP
Nuclear receptor-binding protein

1

1

High-throughput

0.536

High

1462419

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.536

High

1326382

NIN
Ninein

2

11

High-throughput

0.533

High

831652

CCNF
Cyclin-F

1

9

High-throughput

0.515

High

1449511

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

17

Small-scale

0.515

High

1403956

HTF4
Transcription factor 12

1

6

High-throughput

0.515

High

219247

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.513

High

923566

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

1064606

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1207279

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1293569

F131B
Protein FAM131B

1

0

High-throughput

0.513

High

1325858

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1398212

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.513

High

1413875

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.513

High

177730

SMAD7
Mothers against decapentaplegic homolog 7

1

5

High-throughput

0.508

High

188548

NVL
Nuclear valosin-containing protein-like

1

5

Small-scale

0.508

High

519578

MYBB
Myb-related protein B

1

20

Small-scale

0.508

High

555535

SKIL
Ski-like protein

1

1

High-throughput

0.508

High

1097080

PRDX4
Peroxiredoxin-4

1

2

Small-scale

0.508

High

1133370

NC2A
Dr1-associated corepressor

1

5

Small-scale

0.508

High

1154027

SMAD1
Mothers against decapentaplegic homolog 1

1

5

High-throughput

0.508

High

1446491

DCP1A
mRNA-decapping enzyme 1A

1

7

Small-scale

0.508

High

1462420

TACC3
Transforming acidic coiled-coil-containing protein 3

1

15

Small-scale

0.508

High

508838

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

15

High-throughput

0.501

High

1323935

KLH34
Kelch-like protein 34

1

5

High-throughput

0.489

High

1356552

RAB2B
Ras-related protein Rab-2B

1

4

High-throughput

0.489

High

1462421

EMIL1
EMILIN-1

1

13

High-throughput

0.489

High

1410427

HINFP
Histone H4 transcription factor

1

7

Small-scale

0.481

High

294531

CD123
Translation initiation factor eIF2 assembly protein

1

5

High-throughput

0.479

High

324235

CE152
Centrosomal protein of 152 kDa

1

6

High-throughput

0.479

High

373501

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

459802

PROF1
Profilin-1

1

1

High-throughput

0.479

High

468919

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

475063

VIME
Vimentin

1

19

High-throughput

0.479

High

552730

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

4

High-throughput

0.479

High

590036

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

696867

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

12

High-throughput

0.479

High

769517

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

777795

VGFR3
Vascular endothelial growth factor receptor 3

1

13

High-throughput

0.479

High

787101

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

13

High-throughput

0.479

High

832954

CETN2
Centrin-2

1

2

High-throughput

0.479

High

862554

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

895157

EMD
Emerin

1

1

High-throughput

0.479

High

986814

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

1032066

TFAP4
Transcription factor AP-4

1

1

Small-scale

0.479

High

1100544

TIF1B
Transcription intermediary factor 1-beta

1

18

High-throughput

0.479

High

1106125

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

10

High-throughput

0.479

High

1125731

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

9

High-throughput

0.479

High

1178466

CL16A
Protein CLEC16A

1

3

High-throughput

0.479

High

1215531

CE162
Centrosomal protein of 162 kDa

1

20

High-throughput

0.479

High

1276971

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

14

High-throughput

0.479

High

1280936

CNTRL
Centriolin

1

9

High-throughput

0.479

High

1289721

NAA40
N-alpha-acetyltransferase 40

1

7

High-throughput

0.479

High

1322814

CNTRB
Centrobin

1

12

High-throughput

0.479

High

1350502

BICD2
Protein bicaudal D homolog 2

1

15

High-throughput

0.479

High

1368972

GOGA1
Golgin subfamily A member 1

1

12

High-throughput

0.479

High

1395897

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

2

High-throughput

0.479

High

1397562

CI072
Guanine nucleotide exchange factor C9orf72

1

5

High-throughput

0.479

High

1401452

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1429016

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

1446438

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

1458933

ZO2
Tight junction protein 2

1

2

High-throughput

0.479

High

1462415

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

3

High-throughput

0.479

High

904414

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

1143590

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

220636

AKA10
A-kinase anchor protein 10, mitochondrial

1

1

High-throughput

0.445

High

231652

PRKY
Putative serine/threonine-protein kinase PRKY

1

6

High-throughput

0.445

High

331612

KIF4A
Chromosome-associated kinesin KIF4A

1

4

Small-scale

0.445

High

430512

JUN
Transcription factor Jun

1

20

High-throughput

0.445

High

485515

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

Small-scale

0.445

High

541068

PIM1
Serine/threonine-protein kinase pim-1

1

4

High-throughput

0.445

High

626404

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

12

High-throughput

0.445

High

651024

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

20

Small-scale

0.445

High

846530

MATR3
Matrin-3

1

11

Small-scale

0.445

High

896471

ERF
ETS domain-containing transcription factor ERF

1

20

High-throughput

0.445

High

1118636

TBB2A
Tubulin beta-2A chain

1

6

High-throughput

0.445

High

1239338

ARMC6
Armadillo repeat-containing protein 6

1

3

High-throughput

0.445

High

1325801

FXL16
F-box/LRR-repeat protein 16

1

3

High-throughput

0.445

High

1391856

AURKB
Aurora kinase B

1

7

High-throughput

0.445

High

1453277

GRHL1
Grainyhead-like protein 1 homolog

1

5

High-throughput

0.445

High

1462418

T22D4
TSC22 domain family protein 4

1

6

High-throughput

0.445

High

643138

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.437

High

1249330

LMBRL
Protein LMBR1L

1

3

High-throughput

0.437

High

1256635

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.437

High

1331578

CE120
Centrosomal protein of 120 kDa

1

20

High-throughput

0.437

High

1332916

KDF1
Keratinocyte differentiation factor 1

1

1

High-throughput

0.437

High

1369270

RPGR
X-linked retinitis pigmentosa GTPase regulator

1

3

High-throughput

0.437

High

1385720

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

1434237

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1458452

RBL2A
Rab-like protein 2A

1

3

High-throughput

0.437

High

1462416

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.437

High

887335

CEBPA
CCAAT/enhancer-binding protein alpha

1

20

High-throughput

0.408

High

437830

HEPS
Serine protease hepsin

1

3

High-throughput

0.407

High

1366307

LPAR1
Lysophosphatidic acid receptor 1

1

7

High-throughput

0.407

High

1454129

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

7

High-throughput

0.407

High

239250

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

295655

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

690060

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1037081

OC90
Otoconin-90

1

0

High-throughput

0.279

Low

1192212

AMZ1
Archaemetzincin-1

1

0

High-throughput

0.279

Low

1329557

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

1390372

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1393552

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

1458595

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.279

Low

1253682

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025