Protein: IF4B
Eukaryotic translation initiation factor 4B (eIF-4B)

Gene: IF4B, TIF3
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P34167

Gene Ontology (top 5):
GO:0001731 - formation of translation preinitiation complex
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003727 - single-stranded RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757648

RS20
Small ribosomal subunit protein uS10

2

3

Small-scale

0.620

High

757658

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.601

High

434979

RS3
Small ribosomal subunit protein uS3

2

2

Small-scale

0.584

High

757655

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

2

Small-scale

0.584

High

670548

SIS1
Protein SIS1

2

3

High-throughput

0.571

High

523523

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.536

High

544359

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.536

High

757660

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

757661

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.533

High

392507

HSP82
ATP-dependent molecular chaperone HSP82

2

4

High-throughput

0.521

High

757674

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.515

High

518253

IF4A
ATP-dependent RNA helicase eIF4A

1

10

Small-scale

0.501

High

757645

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.494

High

757653

YCFI
Metal resistance protein YCF1

1

1

High-throughput

0.494

High

721821

XPO1
Exportin-1

1

3

High-throughput

0.489

High

757671

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

2

Small-scale

0.481

High

149681

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

359193

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

364455

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

383617

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

433556

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

435881

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

441823

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

502957

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

504140

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

512359

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

689364

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

753282

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

757646

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

757656

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

2

Small-scale

0.479

High

757664

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

757668

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

757669

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

757676

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

581846

SYKC
Lysine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

694517

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

757662

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

757672

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.458

High

358995

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.437

High

359454

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.437

High

554907

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

579142

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.437

High

596809

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

2

High-throughput

0.437

High

679542

CDC48
Cell division control protein 48

1

4

High-throughput

0.437

High

706691

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

750612

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.437

High

757650

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

757652

UME6
Transcriptional regulatory protein UME6

1

1

High-throughput

0.437

High

757654

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

757665

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

High-throughput

0.437

High

757667

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

757670

FIN1
Filament protein FIN1

1

1

Small-scale

0.437

High

757673

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

757675

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.437

High

481576

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.407

High

675875

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.407

High

757657

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.407

High

757666

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.407

High

757659

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.279

Low

94550

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

484750

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

594924

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

737444

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

757647

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

757649

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.249

Low

757651

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

757677

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

757663

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025