Protein: GEMI
Geminin

Gene: GEMI, GMNN
Organism: Homo sapiens
Interactions: 112
UniProt ID: O75496

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

267188

CDT1
DNA replication factor Cdt1

24

3

Small-scale

0.992

High

90130

MCIN
Multicilin

3

2

Small-scale

0.871

High

267174

CC146
Coiled-coil domain-containing protein 146

7

0

High-throughput

0.718

High

267121

CDK2
Cyclin-dependent kinase 2

4

2

High-throughput

0.699

High

267178

ZN439
Zinc finger protein 439

4

1

High-throughput

0.698

High

267154

TFDP1
Transcription factor Dp-1

3

2

High-throughput

0.675

High

267119

CCNA2
Cyclin-A2

4

0

High-throughput

0.670

High

267144

CDK3
Cyclin-dependent kinase 3

3

2

High-throughput

0.667

High

267202

FZR1
Fizzy-related protein homolog

3

2

Small-scale

0.660

High

267110

CDK1
Cyclin-dependent kinase 1

3

2

High-throughput

0.650

High

267148

CDC20
Cell division cycle protein 20 homolog

3

2

Small-scale

0.646

High

267152

MTMR1
Myotubularin-related protein 1

3

0

High-throughput

0.646

High

267135

CDN2A
Cyclin-dependent kinase inhibitor 2A

2

1

High-throughput

0.633

High

66633

ZN785
Zinc finger protein 785

2

1

High-throughput

0.628

High

175626

TRI18
E3 ubiquitin-protein ligase Midline-1

2

2

High-throughput

0.628

High

259539

HMMR
Hyaluronan mediated motility receptor

2

1

High-throughput

0.628

High

267113

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.628

High

267131

CKS2
Cyclin-dependent kinases regulatory subunit 2

2

1

High-throughput

0.628

High

267140

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

1

High-throughput

0.628

High

267158

E2F5
Transcription factor E2F5

2

1

High-throughput

0.628

High

267159

E2F4
Transcription factor E2F4

2

1

High-throughput

0.628

High

267199

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

2

High-throughput

0.628

High

267165

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

1

High-throughput

0.606

High

267107

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.602

High

267128

TYK2
Non-receptor tyrosine-protein kinase TYK2

2

0

High-throughput

0.602

High

267149

SKP2
S-phase kinase-associated protein 2

2

0

High-throughput

0.602

High

267151

TARB1
Probable methyltransferase TARBP1

2

0

High-throughput

0.602

High

267160

CTC1
CST complex subunit CTC1

2

0

High-throughput

0.602

High

267162

KLH22
Kelch-like protein 22

2

0

High-throughput

0.602

High

267166

MSL1
Male-specific lethal 1 homolog

2

0

High-throughput

0.602

High

267170

NPHP3
Nephrocystin-3

2

0

High-throughput

0.602

High

267173

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.602

High

267180

CERK1
Ceramide kinase

2

0

High-throughput

0.602

High

267189

FA83D
Protein FAM83D

2

0

High-throughput

0.602

High

267192

STN1
CST complex subunit STN1

2

0

High-throughput

0.602

High

267195

MYO5C
Unconventional myosin-Vc

2

0

High-throughput

0.602

High

267104

GEMI
Geminin

1

2

High-throughput

0.590

High

267177

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.585

High

267118

ZN250
Zinc finger protein 250

2

0

High-throughput

0.580

High

267147

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

0

High-throughput

0.580

High

267172

SAPC2
Suppressor APC domain-containing protein 2

2

0

High-throughput

0.580

High

267179

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

267187

GLIS2
Zinc finger protein GLIS2

2

0

High-throughput

0.580

High

267138

SMCA4
Transcription activator BRG1

1

1

Small-scale

0.561

High

267130

HXC9
Homeobox protein Hox-C9

1

8

Small-scale

0.554

High

160289

AURKA
Aurora kinase A

1

0

Small-scale

0.537

High

267186

REPI1
Replication initiator 1

1

0

Small-scale

0.537

High

267139

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

267156

CASP8
Caspase-8

1

1

High-throughput

0.536

High

267176

SIX5
Homeobox protein SIX5

1

1

High-throughput

0.536

High

267120

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.518

High

267124

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.518

High

267132

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.513

High

267155

MCM6
DNA replication licensing factor MCM6

1

0

High-throughput

0.513

High

214002

SPOP
Speckle-type POZ protein

1

0

Small-scale

0.513

High

267108

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

267111

CLCB
Clathrin light chain B

1

0

High-throughput

0.513

High

267115

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.513

High

267122

S100P
Protein S100-P

1

0

High-throughput

0.513

High

267150

ATM
Serine-protein kinase ATM

1

0

High-throughput

0.513

High

267164

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

0

High-throughput

0.513

High

267168

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.513

High

267169

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.513

High

267171

TEDC1
Tubulin epsilon and delta complex protein 1

1

0

High-throughput

0.513

High

267185

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

267191

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.513

High

267193

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

0

High-throughput

0.513

High

267105

KAT7
Histone acetyltransferase KAT7

1

1

Small-scale

0.501

High

267106

SIX3
Homeobox protein SIX3

1

2

Small-scale

0.501

High

267117

HXB1
Homeobox protein Hox-B1

1

6

Small-scale

0.501

High

267126

HXD10
Homeobox protein Hox-D10

1

8

Small-scale

0.501

High

267127

MSX1
Homeobox protein MSX-1

1

2

Small-scale

0.501

High

267134

CASP3
Caspase-3

1

1

Small-scale

0.501

High

267143

CSK21
Casein kinase II subunit alpha

1

2

Small-scale

0.501

High

267184

RING2
E3 ubiquitin-protein ligase RING2

1

1

Small-scale

0.501

High

267123

PAX6
Paired box protein Pax-6

1

0

Small-scale

0.480

High

267141

ISL1
Insulin gene enhancer protein ISL-1

1

0

Small-scale

0.480

High

267146

PO5F1
POU domain, class 5, transcription factor 1

1

0

Small-scale

0.480

High

267200

FBX5
F-box only protein 5

1

0

Small-scale

0.479

High

267133

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

267137

SMCA2
Probable global transcription activator SNF2L2

1

1

Small-scale

0.479

High

267157

CDK10
Cyclin-dependent kinase 10

1

3

High-throughput

0.479

High

267182

HDA11
Histone deacetylase 11

1

1

Small-scale

0.479

High

267194

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.479

High

267116

NCF1
Neutrophil cytosol factor 1

1

0

Small-scale

0.460

High

177155

HDAC3
Histone deacetylase 3

1

0

Small-scale

0.458

High

267109

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

267129

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.458

High

267142

WDR5
WD repeat-containing protein 5

1

0

Small-scale

0.458

High

267145

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

267153

CUL3
Cullin-3

1

0

High-throughput

0.458

High

267167

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

267183

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

0

High-throughput

0.458

High

267190

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

267198

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

Small-scale

0.458

High

267181

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.445

High

267136

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

267161

CB068
UPF0561 protein C2orf68

3

0

High-throughput

0.347

High

267163

RUN3A
RUN domain-containing protein 3A

2

0

High-throughput

0.328

High

267201

HECD1
E3 ubiquitin-protein ligase HECTD1

2

0

High-throughput

0.328

High

48855

POTB3
POTE ankyrin domain family member B3

2

0

High-throughput

0.288

High

195662

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

237864

AP180
Clathrin coat assembly protein AP180

1

0

High-throughput

0.279

Low

267125

CALX
Calnexin

1

0

High-throughput

0.279

Low

267175

FAM9C
Protein FAM9C

1

0

High-throughput

0.279

Low

267197

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

267203

ANGP4
Angiopoietin-4

1

0

High-throughput

0.279

Low

267204

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

267114

CADH1
Cadherin-1

1

0

Small-scale

0.249

Low

267196

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

267112

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024