Protein: PXL2A
Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A)

Gene: PXL2A, PRXL2A
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q9BRX8

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0016209 - antioxidant activity
GO:0045670 - regulation of osteoclast differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520982

HLAC
HLA class I histocompatibility antigen, C alpha chain

3

1

High-throughput

0.609

High

470335

NEP
Neprilysin

2

0

High-throughput

0.602

High

1411638

ADPGK
ADP-dependent glucokinase

2

0

High-throughput

0.602

High

607415

HLAG
HLA class I histocompatibility antigen, alpha chain G

2

1

High-throughput

0.574

High

669246

NK1R
Substance-P receptor

2

1

High-throughput

0.574

High

720631

GRPR
Gastrin-releasing peptide receptor

2

1

High-throughput

0.574

High

967347

TSN5
Tetraspanin-5

2

1

High-throughput

0.574

High

1057578

ACHD
Acetylcholine receptor subunit delta

2

1

High-throughput

0.574

High

1163604

RTN1
Reticulon-1

2

3

High-throughput

0.574

High

248769

PEPL
Periplakin

1

1

High-throughput

0.536

High

922006

COPA
Coatomer subunit alpha

1

2

High-throughput

0.536

High

1412005

CRNN
Cornulin

1

1

High-throughput

0.536

High

288004

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.518

High

328446

SCEL
Sciellin

1

0

High-throughput

0.513

High

384721

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.513

High

403003

ANXA1
Annexin A1

1

0

High-throughput

0.513

High

457909

INVO
Involucrin

1

0

High-throughput

0.513

High

518901

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

593482

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

636182

ENDOU
Uridylate-specific endoribonuclease

1

0

High-throughput

0.513

High

654463

EST1
Liver carboxylesterase 1

1

0

High-throughput

0.513

High

721523

ILEU
Leukocyte elastase inhibitor

1

0

High-throughput

0.513

High

722805

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.513

High

748658

DSG3
Desmoglein-3

1

0

High-throughput

0.513

High

1310353

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1411982

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

1411983

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1412008

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

349548

TSN15
Tetraspanin-15

1

1

High-throughput

0.489

High

380478

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

2

High-throughput

0.489

High

607978

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.489

High

699049

CALX
Calnexin

1

1

High-throughput

0.489

High

1098932

KLRD1
Natural killer cells antigen CD94

1

1

High-throughput

0.489

High

1177873

CL12B
C-type lectin domain family 12 member B

1

1

High-throughput

0.489

High

1369004

EVPL
Envoplakin

1

1

High-throughput

0.489

High

1390839

S10AG
Protein S100-A16

1

1

High-throughput

0.489

High

423008

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

375891

RASK
GTPase KRas

1

2

High-throughput

0.479

High

128470

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.458

High

294255

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

1084064

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

0

High-throughput

0.458

High

1255288

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1411994

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1412006

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

333161

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

698007

CALR
Calreticulin

1

1

High-throughput

0.445

High

1316284

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1333975

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

1396031

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1411989

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

75716

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

218695

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

374166

RASN
GTPase NRas

1

2

High-throughput

0.437

High

215638

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

296556

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

319016

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.426

High

360090

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

462601

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

530302

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

535467

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

876979

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

987183

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

1015101

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.426

High

1097038

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1136336

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

1147830

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

1411979

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

1411981

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1411984

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1412011

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

48765

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.407

High

69542

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

104362

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

275553

RTN2
Reticulon-2

1

3

High-throughput

0.407

High

328988

RTN3
Reticulon-3

1

3

High-throughput

0.407

High

773615

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.407

High

888974

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

1009877

NUCB2
Nucleobindin-2

1

1

High-throughput

0.407

High

1146616

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.407

High

1199249

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

1340092

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

1360560

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

1411980

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.407

High

1411991

RTN4
Reticulon-4

1

3

High-throughput

0.407

High

1412002

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.407

High

1412004

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.407

High

1412009

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

1412010

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

1412012

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.407

High

1412007

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

3

0

High-throughput

0.347

High

252287

TLR5
Toll-like receptor 5

2

0

High-throughput

0.328

High

926837

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.328

High

1197874

S39AC
Zinc transporter ZIP12

2

0

High-throughput

0.328

High

1293561

F131B
Protein FAM131B

2

0

High-throughput

0.328

High

1316359

AGRG5
Adhesion G-protein coupled receptor G5

2

0

High-throughput

0.328

High

1329305

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.328

High

1411986

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

1411995

CC50A
Cell cycle control protein 50A

2

0

High-throughput

0.328

High

158305

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.279

Low

437774

HEPS
Serine protease hepsin

1

0

High-throughput

0.279

Low

467593

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.279

Low

615232

IL1RA
Interleukin-1 receptor antagonist protein

1

0

High-throughput

0.279

Low

771846

UD15
UDP-glucuronosyltransferase 1A5

1

0

High-throughput

0.279

Low

823593

ADH7
All-trans-retinol dehydrogenase [NAD(+)] ADH7

1

0

High-throughput

0.279

Low

915027

AK1C2
Aldo-keto reductase family 1 member C2

1

0

High-throughput

0.279

Low

1101410

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

1101645

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1120957

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1239041

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

1278494

GL6D1
Putative glycosyltransferase 6 domain-containing protein 1

1

0

High-throughput

0.279

Low

1355922

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.279

Low

1382048

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

1387671

NXPE2
NXPE family member 2

1

0

High-throughput

0.279

Low

1411992

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

1411998

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.279

Low

1412001

SPG21
Maspardin

1

0

High-throughput

0.279

Low

1412003

SPRR3
Small proline-rich protein 3

1

0

High-throughput

0.279

Low

106564

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

275091

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

418395

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

551229

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low

589548

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

601838

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.249

Low

696354

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

820736

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.249

Low

965198

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1366543

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

50676

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

60402

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.232

Low

211843

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.232

Low

213643

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.232

Low

261263

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

283344

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

567063

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

873298

COPD
Coatomer subunit delta

1

0

High-throughput

0.232

Low

883136

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.232

Low

903774

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

904094

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.232

Low

921760

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

964055

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.232

Low

1027159

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1131363

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.232

Low

1139253

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.232

Low

1139371

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.232

Low

1145666

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

1152846

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

1248653

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.232

Low

1258802

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.232

Low

1327945

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

1330371

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

1337651

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1338212

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.232

Low

1340953

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

1358348

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.232

Low

1381502

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.232

Low

1386188

ASTRA
Protein Aster-A

1

0

High-throughput

0.232

Low

1401857

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low

1411985

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.232

Low

1411987

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.232

Low

1411988

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.232

Low

1411990

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1411993

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1411996

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1411997

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1411999

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low

1412000

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025