Protein: LSM6
U6 snRNA-associated Sm-like protein LSm6

Gene: LSM6
Organism: Homo sapiens
Interactions: 77
UniProt ID: P62312

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

912259

LSM5
U6 snRNA-associated Sm-like protein LSm5

9

20

High-throughput

0.976

High

867408

ICLN
Methylosome subunit pICln

7

7

High-throughput

0.972

High

912139

LSM3
U6 snRNA-associated Sm-like protein LSm3

6

20

High-throughput

0.956

High

912257

LSM2
U6 snRNA-associated Sm-like protein LSm2

6

19

High-throughput

0.949

High

912218

SMD2
Small nuclear ribonucleoprotein Sm D2

5

20

High-throughput

0.935

High

912260

LSM4
U6 snRNA-associated Sm-like protein LSm4

5

19

Small-scale

0.922

High

912256

LSM7
U6 snRNA-associated Sm-like protein LSm7

4

20

High-throughput

0.906

High

167681

LSM1
U6 snRNA-associated Sm-like protein LSm1

4

20

High-throughput

0.902

High

321388

LSM8
U6 snRNA-associated Sm-like protein LSm8

4

20

High-throughput

0.902

High

912234

PATL1
Protein PAT1 homolog 1

4

9

High-throughput

0.902

High

912227

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

4

20

High-throughput

0.900

High

911792

RUXF
Small nuclear ribonucleoprotein F

3

17

High-throughput

0.870

High

202407

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

3

10

High-throughput

0.861

High

157726

GEMI2
Gem-associated protein 2

2

4

High-throughput

0.811

High

269217

WBP4
WW domain-binding protein 4

2

7

High-throughput

0.811

High

538893

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

15

High-throughput

0.811

High

911608

RUXE
Small nuclear ribonucleoprotein E

2

14

High-throughput

0.811

High

912217

SMD1
Small nuclear ribonucleoprotein Sm D1

2

19

High-throughput

0.811

High

912243

LSM10
U7 snRNA-associated Sm-like protein LSm10

2

17

High-throughput

0.811

High

196991

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

4

20

High-throughput

0.697

High

448597

RU1C
U1 small nuclear ribonucleoprotein C

1

7

High-throughput

0.691

High

912021

RUXG
Small nuclear ribonucleoprotein G

1

20

High-throughput

0.691

High

912220

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

16

High-throughput

0.691

High

912233

MEPCE
7SK snRNA methylphosphate capping enzyme

3

6

High-throughput

0.667

High

132809

SDCB1
Syntenin-1

3

0

High-throughput

0.646

High

153629

ANM5
Protein arginine N-methyltransferase 5

2

4

High-throughput

0.628

High

912239

ZN511
Zinc finger protein 511

2

1

High-throughput

0.628

High

912242

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

10

High-throughput

0.628

High

912247

MEP50
Methylosome protein WDR77

2

14

High-throughput

0.628

High

912248

RIOK1
Serine/threonine-protein kinase RIO1

2

4

High-throughput

0.628

High

912251

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

2

3

High-throughput

0.628

High

912252

COPRS
Coordinator of PRMT5 and differentiation stimulator

2

2

High-throughput

0.628

High

912226

RBM39
RNA-binding protein 39

2

11

High-throughput

0.611

High

912254

AKA7G
A-kinase anchor protein 7 isoform gamma

2

7

High-throughput

0.611

High

912258

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

7

Small-scale

0.601

High

199704

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

2

High-throughput

0.536

High

300102

PRP6
Pre-mRNA-processing factor 6

1

20

High-throughput

0.536

High

446568

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

451413

CLCA
Clathrin light chain A

1

5

High-throughput

0.536

High

451662

CLCB
Clathrin light chain B

1

5

High-throughput

0.536

High

508431

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

750209

COIL
Coilin

1

3

High-throughput

0.536

High

817879

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.536

High

878292

NH2L1
NHP2-like protein 1

1

1

High-throughput

0.536

High

912221

SSRP1
FACT complex subunit SSRP1

1

8

High-throughput

0.536

High

912224

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

3

High-throughput

0.536

High

912228

SF3A1
Splicing factor 3A subunit 1

1

7

High-throughput

0.536

High

912230

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

12

High-throughput

0.536

High

912249

RBM42
RNA-binding protein 42

1

13

High-throughput

0.536

High

912250

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.536

High

912222

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

7

High-throughput

0.515

High

912253

IL36B
Interleukin-36 beta

1

0

High-throughput

0.513

High

912231

SMN
Survival motor neuron protein

1

5

Small-scale

0.501

High

912245

TMCO6
Transmembrane and coiled-coil domain-containing protein 6

1

2

High-throughput

0.489

High

823197

DPOD2
DNA polymerase delta subunit 2

1

0

High-throughput

0.486

High

912246

MCRS1
Microspherule protein 1

1

0

High-throughput

0.486

High

912223

TADBP
TAR DNA-binding protein 43

1

6

Small-scale

0.481

High

394478

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

203511

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

5

High-throughput

0.479

High

233341

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

294639

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.479

High

346426

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

379220

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

912219

H4
Histone H4

1

4

High-throughput

0.479

High

912229

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

912232

LARP7
La-related protein 7

1

12

High-throughput

0.479

High

912235

THOC4
THO complex subunit 4

1

10

High-throughput

0.479

High

912236

ZCH18
Zinc finger CCCH domain-containing protein 18

1

8

High-throughput

0.479

High

912237

RHG18
Rho GTPase-activating protein 18

1

5

High-throughput

0.479

High

912238

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

6

Small-scale

0.479

High

912240

LS14A
Protein LSM14 homolog A

1

7

Small-scale

0.479

High

912244

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

912255

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

912225

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

912241

DPTOR
DEP domain-containing mTOR-interacting protein

1

2

Small-scale

0.437

High

831182

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

211300

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

7

High-throughput

0.407

High


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Last updated: 15 Jul 2024