Protein: EXO1
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)

Gene: EXO1
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9UQ84

Gene Ontology (top 5):
GO:0000729 - DNA double-strand break processing
GO:0002455 - humoral immune response mediated by circulating immunoglobulin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004523 - RNA-DNA hybrid ribonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

517542

PCNA
Proliferating cell nuclear antigen

3

6

Small-scale

0.840

High

776427

MLH1
DNA mismatch repair protein Mlh1

10

5

Small-scale

0.755

High

794340

MSH2
DNA mismatch repair protein Msh2

8

6

Small-scale

0.749

High

982630

1433F
14-3-3 protein eta

5

10

Small-scale

0.716

High

910169

1433E
14-3-3 protein epsilon

4

3

Small-scale

0.701

High

927667

1433Z
14-3-3 protein zeta/delta

3

10

Small-scale

0.678

High

867670

BLM
RecQ-like DNA helicase BLM

3

2

Small-scale

0.667

High

683822

1433B
14-3-3 protein beta/alpha

5

10

Small-scale

0.660

High

1305794

CTIP
DNA endonuclease RBBP8

3

0

Small-scale

0.639

High

647387

1433T
14-3-3 protein theta

4

10

Small-scale

0.632

High

905269

1433G
14-3-3 protein gamma

4

10

Small-scale

0.629

High

1310827

WDR83
WD repeat domain-containing protein 83

3

1

High-throughput

0.609

High

594227

MSH3
DNA mismatch repair protein Msh3

2

6

Small-scale

0.595

High

869899

PMS2
Mismatch repair endonuclease PMS2

2

5

Small-scale

0.584

High

918149

H4
Histone H4

2

1

Small-scale

0.563

High

1357850

DCAF1
DDB1- and CUL4-associated factor 1

1

1

Small-scale

0.561

High

1031643

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.537

High

1326249

SENP6
Sentrin-specific protease 6

1

0

Small-scale

0.537

High

508779

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

855582

MSH6
DNA mismatch repair protein Msh6

1

7

High-throughput

0.536

High

996966

SSRP1
FACT complex subunit SSRP1

1

4

High-throughput

0.536

High

1087491

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.536

High

1158599

L2GL2
LLGL scribble cell polarity complex component 2

1

1

High-throughput

0.536

High

1205451

ZGRF1
5'-3' DNA helicase ZGRF1

1

5

Small-scale

0.536

High

1334267

ARP5
Actin-related protein 5

1

1

High-throughput

0.536

High

1350421

MYEF2
Myelin expression factor 2

1

2

High-throughput

0.536

High

684402

1433S
14-3-3 protein sigma

1

10

Small-scale

0.527

High

441043

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.513

High

602610

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.513

High

930458

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

1060968

IMB1
Importin subunit beta-1

1

1

Small-scale

0.501

High

1355318

MLH3
DNA mismatch repair protein Mlh3

1

5

Small-scale

0.501

High

1068703

PLEC
Plectin

1

0

High-throughput

0.493

High

1298897

PCFT
Proton-coupled folate transporter

1

0

High-throughput

0.493

High

1160014

KLC3
Kinesin light chain 3

1

1

High-throughput

0.489

High

134982

IMA3
Importin subunit alpha-3

1

0

Small-scale

0.480

High

415109

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.479

High

538629

CCNB1
G2/mitotic-specific cyclin-B1

1

7

Small-scale

0.479

High

590238

CCNA2
Cyclin-A2

1

6

Small-scale

0.479

High

625644

CDK2
Cyclin-dependent kinase 2

1

6

Small-scale

0.479

High

749963

BRCA1
Breast cancer type 1 susceptibility protein

1

1

Small-scale

0.479

High

780337

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

869856

PMS1
PMS1 protein homolog 1

1

5

High-throughput

0.479

High

943811

CCNA1
Cyclin-A1

1

6

Small-scale

0.479

High

1267266

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

Small-scale

0.479

High

246296

NBN
Nibrin

1

0

Small-scale

0.458

High

1082456

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.458

High

1271515

KAT2B
Histone acetyltransferase KAT2B

1

0

Small-scale

0.458

High

1332785

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1357004

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.458

High

529923

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High


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Last updated: 15 Jul 2024