Protein: INT10
Integrator complex subunit 10 (Int10)

Gene: INT10, INTS10
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q9NVR2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016180 - snRNA processing
GO:0032039 - integrator complex
GO:0034243 - regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1403175

INT14
Integrator complex subunit 14

6

1

Small-scale

0.952

High

1215021

INT11
Integrator complex subunit 11

3

1

Small-scale

0.827

High

1450778

INT6
Integrator complex subunit 6

3

0

Small-scale

0.784

High

1450702

INT13
Integrator complex subunit 13

5

0

Small-scale

0.692

High

451709

PGK2
Phosphoglycerate kinase 2

2

0

High-throughput

0.602

High

994397

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

0

High-throughput

0.602

High

130630

SPT5H
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

621987

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

0

Small-scale

0.585

High

723113

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

Small-scale

0.585

High

1450308

INT9
Integrator complex subunit 9

2

1

Small-scale

0.584

High

1330241

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

1398671

INT15
Integrator complex subunit 15

1

1

Small-scale

0.575

High

397055

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1229210

INT3
Integrator complex subunit 3

2

0

Small-scale

0.559

High

1243335

INT5
Integrator complex subunit 5

2

0

Small-scale

0.559

High

1323850

INT1
Integrator complex subunit 1

2

0

Small-scale

0.559

High

1393580

INT4
Integrator complex subunit 4

2

0

Small-scale

0.559

High

954751

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.547

High

1232605

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

621766

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.513

High

908468

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

923552

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

959071

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

1015320

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.513

High

1065460

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

894201

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

143292

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

474330

NFIC
Nuclear factor 1 C-type

1

4

High-throughput

0.479

High

1088055

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

1133696

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

1367402

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1450777

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.479

High

192867

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

667477

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

790100

ZEB1
Zinc finger E-box-binding homeobox 1

1

0

Small-scale

0.458

High

851681

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

912137

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

Small-scale

0.458

High

980424

H4
Histone H4

1

0

High-throughput

0.458

High

1029955

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1048110

TLE3
Transducin-like enhancer protein 3

1

0

High-throughput

0.458

High

1260322

INT8
Integrator complex subunit 8

1

0

Small-scale

0.458

High

1385757

INT12
Integrator complex subunit 12

1

0

Small-scale

0.458

High

1430044

INT2
Integrator complex subunit 2

1

0

Small-scale

0.458

High

1450522

INT7
Integrator complex subunit 7

1

0

Small-scale

0.458

High

1450775

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1450776

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1450779

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

401574

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

Small-scale

0.438

High

533781

CLUS
Clusterin

1

0

High-throughput

0.438

High

457737

TBB5
Tubulin beta chain

1

0

Small-scale

0.426

High

911403

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.426

High

1334367

IN80E
INO80 complex subunit E

1

0

High-throughput

0.426

High

1279984

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.316

High

1201074

ACTBL
Beta-actin-like protein 2

1

0

High-throughput

0.279

Low

1412766

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.279

Low

1256931

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1448491

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

1194798

GRPL2
GLIPR1-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025