Protein: INT5
Integrator complex subunit 5 (Int5)

Gene: INT5, INTS5
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q6P9B9

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

717864

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

3

1

High-throughput

0.867

High

994266

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

1

High-throughput

0.811

High

1243311

INT1
Integrator complex subunit 1

2

1

High-throughput

0.789

High

774433

BASI
Basigin

3

1

High-throughput

0.667

High

1243306

INT8
Integrator complex subunit 8

3

0

Small-scale

0.649

High

1243315

TM171
Transmembrane protein 171

3

0

High-throughput

0.638

High

1243338

INT6
Integrator complex subunit 6

3

1

Small-scale

0.633

High

718136

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.618

High

977526

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.618

High

1206356

INT6L
Integrator complex subunit 6-like

2

1

High-throughput

0.611

High

1243327

SOSB1
SOSS complex subunit B1

2

1

High-throughput

0.611

High

1243332

INT9
Integrator complex subunit 9

2

3

High-throughput

0.611

High

1243316

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.602

High

1243331

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

High-throughput

0.602

High

1243322

INT4
Integrator complex subunit 4

1

0

High-throughput

0.586

High

1243323

INT15
Integrator complex subunit 15

1

0

High-throughput

0.586

High

1243328

INT2
Integrator complex subunit 2

1

0

High-throughput

0.586

High

218337

TGON2
Trans-Golgi network integral membrane protein 2

2

0

High-throughput

0.585

High

1243326

INT14
Integrator complex subunit 14

2

0

High-throughput

0.585

High

950540

KR108
Keratin-associated protein 10-8

2

0

High-throughput

0.580

High

879797

NPY2R
Neuropeptide Y receptor type 2

2

1

High-throughput

0.574

High

396344

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1243335

INT10
Integrator complex subunit 10

2

0

Small-scale

0.559

High

182601

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.536

High

956912

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.536

High

380073

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

0

High-throughput

0.528

High

64042

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

209040

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

388224

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

407187

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

445206

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

486577

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

533694

CLUS
Clusterin

1

0

High-throughput

0.513

High

615559

NELFE
Negative elongation factor E

1

0

High-throughput

0.513

High

634770

GRAH
Granzyme H

1

0

High-throughput

0.513

High

848506

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.513

High

854116

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

923505

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

1053016

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1103704

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.513

High

1243308

SKA3
Spindle and kinetochore-associated protein 3

1

0

High-throughput

0.513

High

1243309

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.513

High

1243312

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1243317

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1243337

CLC2D
C-type lectin domain family 2 member D

1

0

High-throughput

0.513

High

1243339

PALD
Paladin

1

0

High-throughput

0.513

High

1243343

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

165964

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

771155

APJ
Apelin receptor

1

2

High-throughput

0.489

High

1101538

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.489

High

1243344

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

1243345

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

1214988

INT11
Integrator complex subunit 11

1

3

High-throughput

0.479

High

1243310

ZN687
Zinc finger protein 687

1

1

High-throughput

0.479

High

1243318

ZN592
Zinc finger protein 592

1

1

High-throughput

0.479

High

1243319

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1243320

SOSB2
SOSS complex subunit B2

1

1

High-throughput

0.479

High

138176

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

157512

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

192827

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

272267

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

621669

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

621898

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

667342

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

714204

PML
Protein PML

1

0

High-throughput

0.458

High

722995

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.458

High

904846

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

912075

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

912194

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.458

High

942689

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

954706

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.458

High

976104

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

979847

H4
Histone H4

1

0

High-throughput

0.458

High

983668

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

1004719

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1229163

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1229480

NAIF1
Nuclear apoptosis-inducing factor 1

1

0

High-throughput

0.458

High

1243305

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1243314

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1243321

INT12
Integrator complex subunit 12

1

0

High-throughput

0.458

High

1243325

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1243329

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1243333

INT7
Integrator complex subunit 7

1

0

High-throughput

0.458

High

1243334

INT13
Integrator complex subunit 13

1

0

High-throughput

0.458

High

1243340

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

143449

E2F3
Transcription factor E2F3

1

0

Small-scale

0.426

High

295592

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.426

High

378122

TNFA
Tumor necrosis factor

3

0

High-throughput

0.347

High

466919

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.328

High

749218

CD70
CD70 antigen

2

0

High-throughput

0.328

High

821734

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

1243342

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

139241

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

472185

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

583937

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

0

High-throughput

0.279

Low

880159

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

914281

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1159204

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

1243307

CLC14
C-type lectin domain family 14 member A

1

0

High-throughput

0.279

Low

1243313

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1243324

OPALI
Opalin

1

0

High-throughput

0.279

Low

1243330

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1243336

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1243341

PCDAC
Protocadherin alpha-12

1

0

High-throughput

0.279

Low

70289

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.251

Low

412110

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1243304

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025