Protein: INT2
Integrator complex subunit 2 (Int2)

Gene: INT2, INTS2
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9H0H0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016020 - membrane
GO:0016180 - snRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

994367

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

3

Small-scale

0.694

High

262300

SCN2B
Sodium channel regulatory subunit beta-2

4

1

High-throughput

0.630

High

717990

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.611

High

1403168

INT14
Integrator complex subunit 14

2

1

High-throughput

0.611

High

1430046

PD1L1
Programmed cell death 1 ligand 1

2

2

High-throughput

0.611

High

771231

APJ
Apelin receptor

3

3

High-throughput

0.604

High

1293902

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.604

High

596777

DPEP1
Dipeptidase 1

2

0

High-throughput

0.602

High

1349111

F174A
Membrane protein FAM174A

2

0

High-throughput

0.602

High

638518

FPR1
fMet-Leu-Phe receptor

2

4

High-throughput

0.601

High

1243328

INT5
Integrator complex subunit 5

1

0

High-throughput

0.586

High

1323839

INT1
Integrator complex subunit 1

1

0

High-throughput

0.586

High

1430050

INT6
Integrator complex subunit 6

2

1

Small-scale

0.584

High

222199

NCK2
Cytoplasmic protein NCK2

2

0

High-throughput

0.580

High

1180021

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.580

High

1430041

DEFI6
Differentially expressed in FDCP 6 homolog

2

0

High-throughput

0.580

High

50687

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.576

High

388293

GLPA
Glycophorin-A

2

0

High-throughput

0.576

High

396911

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

675153

TNR6
Tumor necrosis factor receptor superfamily member 6

2

1

High-throughput

0.558

High

133311

P2Y10
Putative P2Y purinoceptor 10

2

3

High-throughput

0.549

High

683334

TNR5
Tumor necrosis factor receptor superfamily member 5

2

1

High-throughput

0.549

High

754094

CD80
T-lymphocyte activation antigen CD80

2

2

High-throughput

0.549

High

1101659

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

4

High-throughput

0.549

High

1430043

TMM9B
Transmembrane protein 9B

2

1

High-throughput

0.549

High

218747

TGON2
Trans-Golgi network integral membrane protein 2

2

0

High-throughput

0.547

High

954741

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.547

High

351963

S1PR4
Sphingosine 1-phosphate receptor 4

1

2

High-throughput

0.536

High

872731

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.536

High

1407300

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.536

High

71248

HIDE1
Protein HIDE1

1

0

High-throughput

0.513

High

130609

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

291864

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

486616

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

542213

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

621961

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

634803

GRAH
Granzyme H

1

0

High-throughput

0.513

High

723082

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

854580

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.513

High

923534

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

959051

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

1065422

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1291680

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1324859

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1406545

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

1430040

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

1430045

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

166039

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

210422

MTLR
Motilin receptor

1

2

High-throughput

0.489

High

733069

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

835382

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

2

High-throughput

0.489

High

880201

PTH2R
Parathyroid hormone 2 receptor

1

2

High-throughput

0.489

High

1291890

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

4

High-throughput

0.489

High

1340028

GP150
Probable G-protein coupled receptor 150

1

1

High-throughput

0.489

High

1430047

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

1430052

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

216538

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

246933

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

621740

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.479

High

977583

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

3

High-throughput

0.479

High

1155747

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1367230

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

242871

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

593212

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

897970

CDK9
Cyclin-dependent kinase 9

1

0

High-throughput

0.458

High

955567

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.458

High

980296

H4
Histone H4

1

0

High-throughput

0.458

High

1005082

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1114258

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1124412

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

1215014

INT11
Integrator complex subunit 11

1

0

Small-scale

0.458

High

1229201

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1255468

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1430042

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1430044

INT10
Integrator complex subunit 10

1

0

Small-scale

0.458

High

1430054

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

886130

CXCR3
C-X-C chemokine receptor type 3

1

3

High-throughput

0.445

High

1366222

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.445

High

1101307

SLAF1
Signaling lymphocytic activation molecule

1

2

High-throughput

0.437

High

166409

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

1292874

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.426

High

1395659

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.426

High

1430051

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.426

High

669363

ACKR3
Atypical chemokine receptor 3

1

3

High-throughput

0.407

High

1153432

CD226
CD226 antigen

1

2

High-throughput

0.407

High

749275

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1430049

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

139312

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

253899

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

914341

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

932348

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

1186231

CEA21
Cell adhesion molecule CEACAM21

1

0

High-throughput

0.279

Low

1249845

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1281714

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1363140

CLC2B
C-type lectin domain family 2 member B

1

0

High-throughput

0.279

Low

1399607

OPALI
Opalin

1

0

High-throughput

0.279

Low

1430048

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1256924

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

2120

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low

704073

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

1279082

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low

1292407

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.232

Low

1430053

NPTN
Neuroplastin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025