Protein: KDSR
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)

Gene: KDSR
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q06136

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006666 - 3-keto-sphinganine metabolic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986112

SG196
Protein O-mannose kinase

3

1

High-throughput

0.667

High

961636

REEP5
Receptor expression-enhancing protein 5

2

7

High-throughput

0.628

High

986087

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

17

High-throughput

0.618

High

237802

TSN3
Tetraspanin-3

2

8

High-throughput

0.611

High

179353

MRP4
ATP-binding cassette sub-family C member 4

1

2

High-throughput

0.536

High

209326

TSN6
Tetraspanin-6

1

8

High-throughput

0.536

High

217160

EXTL3
Exostosin-like 3

1

1

High-throughput

0.536

High

237725

TSN2
Tetraspanin-2

1

8

High-throughput

0.536

High

303901

YIF1A
Protein YIF1A

1

2

High-throughput

0.536

High

307024

RTN3
Reticulon-3

1

11

High-throughput

0.536

High

446020

CD63
CD63 antigen

1

9

High-throughput

0.536

High

643225

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

1

High-throughput

0.536

High

648012

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

1

High-throughput

0.536

High

656950

5HT1B
5-hydroxytryptamine receptor 1B

1

2

High-throughput

0.536

High

714653

CNR2
Cannabinoid receptor 2

1

8

Small-scale

0.536

High

725422

COPB2
Coatomer subunit beta'

1

8

High-throughput

0.536

High

750650

INGR2
Interferon gamma receptor 2

1

2

High-throughput

0.536

High

986084

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

2

High-throughput

0.536

High

986089

YIF1B
Protein YIF1B

1

2

High-throughput

0.536

High

986091

CERS6
Ceramide synthase 6

1

3

High-throughput

0.536

High

986097

GOGA5
Golgin subfamily A member 5

1

1

High-throughput

0.536

High

986098

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.536

High

986102

CERS2
Ceramide synthase 2

1

3

High-throughput

0.536

High

986103

REEP6
Receptor expression-enhancing protein 6

1

7

High-throughput

0.536

High

986107

TACAN
Ion channel TACAN

1

4

High-throughput

0.536

High

986120

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

2

High-throughput

0.536

High

986121

PRAF1
Prenylated Rab acceptor protein 1

1

3

High-throughput

0.536

High

986124

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.536

High

281607

WFS1
Wolframin

1

1

High-throughput

0.515

High

240887

S19A2
Thiamine transporter 1

1

0

High-throughput

0.513

High

415303

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.513

High

503213

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.513

High

578310

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.513

High

623245

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

High-throughput

0.513

High

735928

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

986086

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.513

High

986088

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.513

High

986095

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.513

High

986100

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.513

High

986105

TLCD4
TLC domain-containing protein 4

1

0

High-throughput

0.513

High

986108

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

986111

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.513

High

986115

FKRP
Ribitol 5-phosphate transferase FKRP

1

0

High-throughput

0.513

High

986123

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

475655

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

986085

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.494

High

363587

TTHY
Transthyretin

1

0

High-throughput

0.493

High

388397

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

119631

STXB3
Syntaxin-binding protein 3

1

3

High-throughput

0.489

High

245330

RAMP3
Receptor activity-modifying protein 3

1

2

High-throughput

0.489

High

326057

TSN15
Tetraspanin-15

1

9

High-throughput

0.489

High

488692

ARAF
Serine/threonine-protein kinase A-Raf

1

4

High-throughput

0.489

High

583875

CD53
Leukocyte surface antigen CD53

1

9

High-throughput

0.489

High

600756

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

5

High-throughput

0.489

High

645794

CD27
CD27 antigen

1

1

High-throughput

0.489

High

783632

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

4

High-throughput

0.489

High

905507

TSN5
Tetraspanin-5

1

10

High-throughput

0.489

High

986090

SARM1
NAD(+) hydrolase SARM1

1

3

High-throughput

0.489

High

986093

STX12
Syntaxin-12

1

2

High-throughput

0.489

High

986096

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.489

High

986099

LPAR1
Lysophosphatidic acid receptor 1

1

7

High-throughput

0.489

High

986109

TTYH3
Protein tweety homolog 3

1

2

High-throughput

0.489

High

986113

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.489

High

986116

LPAR2
Lysophosphatidic acid receptor 2

1

10

High-throughput

0.489

High

986117

GPR35
G-protein coupled receptor 35

1

6

High-throughput

0.489

High

815770

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

4

Small-scale

0.479

High

231503

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

205304

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

552557

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

651023

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

720291

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

986092

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

986101

TSN17
Tetraspanin-17

1

10

High-throughput

0.437

High

986118

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

63538

T238L
Transmembrane protein 238-like

1

0

Small-scale

0.426

High

986094

RELL1
RELT-like protein 1

2

0

High-throughput

0.328

High

117392

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.279

Low

210556

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.279

Low

210653

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.279

Low

236297

B4GT3
Beta-1,4-galactosyltransferase 3

1

0

High-throughput

0.279

Low

311162

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.279

Low

333459

CYB
Cytochrome b

1

0

High-throughput

0.279

Low

579526

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.279

Low

986104

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.279

Low

986106

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.279

Low

986110

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.279

Low

986114

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.279

Low

986119

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

986122

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

0

High-throughput

0.279

Low

986125

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.279

Low

575397

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

725647

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024