Protein: MANBA
Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase)

Gene: MANBA
Organism: Homo sapiens
Interactions: 71
UniProt ID: O00462

Gene Ontology (top 5):
GO:0004567 - beta-mannosidase activity
GO:0005886 - plasma membrane
GO:0006516 - glycoprotein catabolic process
GO:0009313 - oligosaccharide catabolic process
GO:0035577 - azurophil granule membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

136572

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.691

High

136597

CEAM8
Cell adhesion molecule CEACAM8

1

1

High-throughput

0.691

High

136607

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

0

High-throughput

0.638

High

136614

KIRR2
Kin of IRRE-like protein 2

3

0

High-throughput

0.638

High

136608

TAZ
Tafazzin

3

1

High-throughput

0.609

High

136586

CATG
Cathepsin G

2

6

High-throughput

0.601

High

136636

FBX6
F-box only protein 6

2

3

High-throughput

0.584

High

136584

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.575

High

62189

PRS37
Probable inactive serine protease 37

2

6

High-throughput

0.574

High

136578

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

2

1

High-throughput

0.574

High

136638

KLK11
Kallikrein-11

2

2

High-throughput

0.558

High

136595

CMA1
Chymase

2

6

High-throughput

0.549

High

136581

LV657
Immunoglobulin lambda variable 6-57

1

0

High-throughput

0.546

High

136588

CFC1
Cryptic protein

1

1

High-throughput

0.536

High

136589

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

136594

IDS
Iduronate 2-sulfatase

1

2

High-throughput

0.536

High

136596

PRTN3
Myeloblastin

1

5

High-throughput

0.536

High

136600

WNT3A
Protein Wnt-3a

1

1

High-throughput

0.536

High

136621

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.536

High

136623

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.536

High

136639

FBX2
F-box only protein 2

1

3

High-throughput

0.536

High

136574

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

136577

RAMP1
Receptor activity-modifying protein 1

1

0

High-throughput

0.513

High

136598

PA2G5
Phospholipase A2 group V

1

0

High-throughput

0.513

High

136606

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.513

High

136571

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.489

High

136576

PI15
Peptidase inhibitor 15

1

1

High-throughput

0.489

High

136582

C1QA
Complement C1q subcomponent subunit A

1

4

High-throughput

0.489

High

136583

C1QB
Complement C1q subcomponent subunit B

1

5

High-throughput

0.489

High

136585

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

136591

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.489

High

136592

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

136593

KLK2
Kallikrein-2

1

4

High-throughput

0.489

High

136599

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

1

High-throughput

0.489

High

136603

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

5

High-throughput

0.489

High

136615

LYZL1
Lysozyme-like protein 1

1

2

High-throughput

0.489

High

136618

LYZL2
Lysozyme-like protein 2

1

2

High-throughput

0.489

High

136628

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.489

High

136632

WN10A
Protein Wnt-10a

1

1

High-throughput

0.489

High

136635

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.489

High

136575

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

136625

LIPH
Lipase member H

1

0

High-throughput

0.458

High

63130

CL18A
C-type lectin domain family 18 member A

1

3

High-throughput

0.437

High

136613

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

136617

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

136573

CLGN
Calmegin

1

3

High-throughput

0.407

High

136604

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

136580

SG1D1
Secretoglobin family 1D member 1

3

0

High-throughput

0.345

High

136602

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.328

High

136609

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

136619

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

136579

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.279

Low

136590

PIP
Prolactin-inducible protein

1

0

High-throughput

0.279

Low

136601

INHBE
Inhibin beta E chain

1

0

High-throughput

0.279

Low

136605

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

136610

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

136611

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

136612

NMS
Neuromedin-S

1

0

High-throughput

0.279

Low

136616

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

136620

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

136624

NNRE
NAD(P)H-hydrate epimerase

1

0

High-throughput

0.279

Low

136626

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

136631

BRNP2
BMP/retinoic acid-inducible neural-specific protein 2

1

0

High-throughput

0.279

Low

136633

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

136637

COKA1

1

0

High-throughput

0.279

Low

136587

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

136622

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

136627

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.249

Low

136629

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low

136630

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

136634

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025