Protein: CKS1
Cyclin-dependent kinases regulatory subunit 1 (CKS-1)

Gene: CKS1, CKS1B
Organism: Homo sapiens
Interactions: 96
UniProt ID: P61024

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0007346 - regulation of mitotic cell cycle
GO:0019005 - SCF ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625283

CDK2
Cyclin-dependent kinase 2

17

20

Small-scale

0.987

High

414843

CDK1
Cyclin-dependent kinase 1

13

20

Small-scale

0.984

High

895413

CDK3
Cyclin-dependent kinase 3

7

20

Small-scale

0.965

High

895451

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

3

7

High-throughput

0.871

High

706792

CKS2
Cyclin-dependent kinases regulatory subunit 2

2

5

High-throughput

0.811

High

895424

SKP2
S-phase kinase-associated protein 2

17

2

Small-scale

0.765

High

590156

CCNA2
Cyclin-A2

8

20

Small-scale

0.749

High

895410

SKP1
S-phase kinase-associated protein 1

8

1

Small-scale

0.749

High

804090

CDN1B
Cyclin-dependent kinase inhibitor 1B

6

3

Small-scale

0.731

High

895466

CILK1
Serine/threonine-protein kinase ICK

2

20

High-throughput

0.726

High

538505

CCNB1
G2/mitotic-specific cyclin-B1

5

20

Small-scale

0.718

High

477685

TRI49
Tripartite motif-containing protein 49

5

2

High-throughput

0.717

High

758171

CDN1A
Cyclin-dependent kinase inhibitor 1

4

3

High-throughput

0.699

High

895409

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

5

High-throughput

0.698

High

895426

IKZF1
DNA-binding protein Ikaros

3

3

High-throughput

0.675

High

895427

CUL1
Cullin-1

4

0

Small-scale

0.672

High

303840

CCNB2
G2/mitotic-specific cyclin-B2

3

20

Small-scale

0.670

High

895412

XIAP
E3 ubiquitin-protein ligase XIAP

4

0

High-throughput

0.668

High

895422

CDC20
Cell division cycle protein 20 homolog

3

6

Small-scale

0.667

High

64003

SPDE4
Speedy protein E4

3

5

High-throughput

0.665

High

895417

ARI5A
AT-rich interactive domain-containing protein 5A

3

0

High-throughput

0.646

High

267140

GEMI
Geminin

2

1

High-throughput

0.628

High

331636

CCNE2
G1/S-specific cyclin-E2

2

20

High-throughput

0.628

High

624570

CCNE1
G1/S-specific cyclin-E1

2

20

High-throughput

0.628

High

895420

EF1A2
Elongation factor 1-alpha 2

2

2

High-throughput

0.628

High

895452

CDT1
DNA replication factor Cdt1

2

1

High-throughput

0.628

High

895414

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

895456

CDK12
Cyclin-dependent kinase 12

1

16

High-throughput

0.618

High

551105

ITF2
Transcription factor 4

3

1

High-throughput

0.616

High

837790

MEOX1
Homeobox protein MOX-1

3

6

High-throughput

0.616

High

624418

CCNC
Cyclin-C

2

20

High-throughput

0.606

High

641361

PAX6
Paired box protein Pax-6

2

1

High-throughput

0.606

High

895415

PAX5
Paired box protein Pax-5

2

2

High-throughput

0.606

High

895449

ASPP1
Apoptosis-stimulating of p53 protein 1

2

1

High-throughput

0.606

High

895450

HTF4
Transcription factor 12

2

1

High-throughput

0.606

High

895462

IKZF3
Zinc finger protein Aiolos

2

3

High-throughput

0.606

High

895440

CSN6
COP9 signalosome complex subunit 6

2

0

High-throughput

0.595

High

895463

FZR1
Fizzy-related protein homolog

2

6

Small-scale

0.584

High

252980

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

895421

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

895423

STF1
Steroidogenic factor 1

2

0

High-throughput

0.580

High

895428

SRTD2
SERTA domain-containing protein 2

2

0

High-throughput

0.580

High

895431

U1SBP
U11/U12 small nuclear ribonucleoprotein 35 kDa protein

2

0

High-throughput

0.580

High

895453

IKZF5
Zinc finger protein Pegasus

2

3

High-throughput

0.574

High

536771

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.573

High

477693

TR49C
Tripartite motif-containing protein 49C

2

2

High-throughput

0.553

High

895429

TRI14
Tripartite motif-containing protein 14

2

1

High-throughput

0.553

High

895419

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

610204

CCNO
Cyclin-O

1

20

High-throughput

0.536

High

895436

SPDYC
Speedy protein C

1

5

High-throughput

0.536

High

150340

CDX4
Homeobox protein CDX-4

1

4

High-throughput

0.523

High

642040

KRA59
Keratin-associated protein 5-9

1

1

High-throughput

0.523

High

895446

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

895464

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

431710

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.501

High

672799

CDC27
Cell division cycle protein 27 homolog

1

2

Small-scale

0.501

High

895411

CCNA1
Cyclin-A1

1

20

Small-scale

0.501

High

895430

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.501

High

895454

PKHG2
Pleckstrin homology domain-containing family G member 2

1

1

High-throughput

0.489

High

122167

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

Small-scale

0.480

High

622417

CCND1
G1/S-specific cyclin-D1

1

20

Small-scale

0.479

High

895416

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.479

High

895425

ORC1
Origin recognition complex subunit 1

1

1

Small-scale

0.479

High

895439

Q6FHY5
MEOX2 protein

1

6

High-throughput

0.470

High

895438

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

Small-scale

0.460

High

346379

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

895441

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

895443

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

895458

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

422005

LDHB
L-lactate dehydrogenase B chain

1

1

Small-scale

0.457

High

895418

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.457

High

895433

SPDE7
Putative speedy protein E7

1

5

High-throughput

0.445

High

837902

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.439

High

895444

CBY2
Protein chibby homolog 2

3

0

High-throughput

0.352

High

895455

ROP1A
Ropporin-1A

3

0

High-throughput

0.352

High

895459

SEPT3
Neuronal-specific septin-3

3

0

High-throughput

0.352

High

330070

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.316

High

895435

CT451
Cancer/testis antigen family 45 member A1

2

0

High-throughput

0.316

High

895437

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

895442

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

0

High-throughput

0.316

High

895447

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

0

High-throughput

0.316

High

895448

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

895457

LHX3
LIM/homeobox protein Lhx3

2

0

High-throughput

0.316

High

895460

DCDC2
Doublecortin domain-containing protein 2

2

0

High-throughput

0.316

High

895461

SRTD1
SERTA domain-containing protein 1

2

0

High-throughput

0.316

High

895465

WASF3
Actin-binding protein WASF3

2

0

High-throughput

0.316

High

895467

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.316

High

895432

SMTL2
Smoothelin-like protein 2

2

0

High-throughput

0.313

High

889743

KR109
Keratin-associated protein 10-9

1

0

High-throughput

0.299

High

895445

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

659266

DUS1
Dual specificity protein phosphatase 1

2

0

Small-scale

0.298

High

304433

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.279

Low

837597

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

0

High-throughput

0.279

Low

895434

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

102153

SUMO5
Small ubiquitin-related modifier 5

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024