Protein: PKH1
Serine/threonine-protein kinase PKH1 (EC 2.7.11.1) (3-phosphoinositide-dependent protein kinase 1)

Gene: PKH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q03407

Gene Ontology (top 5):
GO:0000196 - cell integrity MAPK cascade
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441235

KAPA
cAMP-dependent protein kinase type 1

2

16

Small-scale

0.825

High

437954

KAPC
cAMP-dependent protein kinase type 3

2

16

Small-scale

0.825

High

548922

SCH9
Serine/threonine-protein kinase SCH9

2

17

Small-scale

0.799

High

554730

YPK1
Serine/threonine-protein kinase YPK1

2

17

Small-scale

0.778

High

918670

PIL1
Sphingolipid long chain base-responsive protein PIL1

10

4

Small-scale

0.754

High

584386

GCN2
eIF-2-alpha kinase GCN2

1

18

Small-scale

0.747

High

1042693

PKH2
Serine/threonine-protein kinase PKH2

2

19

High-throughput

0.743

High

441393

KAPB
cAMP-dependent protein kinase type 2

1

17

Small-scale

0.724

High

1042692

LSP1
Sphingolipid long chain base-responsive protein LSP1

4

4

Small-scale

0.692

High

623007

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.691

High

865535

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

19

High-throughput

0.691

High

617952

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

18

Small-scale

0.647

High

632917

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

3

Small-scale

0.647

High

807131

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

11

High-throughput

0.618

High

393242

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.618

High

448563

RHO1
GTP-binding protein RHO1

1

20

High-throughput

0.618

High

527542

HSP72
Heat shock protein SSA2

2

20

High-throughput

0.552

High

819642

SSB2
Ribosome-associated molecular chaperone SSB2

2

20

High-throughput

0.552

High

546067

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.536

High

150236

YRF14
Y' element ATP-dependent helicase protein 1 copy 4

1

1

High-throughput

0.508

High

478639

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

4

Small-scale

0.501

High

737767

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

10

Small-scale

0.501

High

1042690

MYO5
Myosin-5

1

14

Small-scale

0.481

High

149930

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

433824

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

442085

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

504391

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

512619

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

513190

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

674805

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

778507

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

1025018

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.479

High

638816

REB1
DNA-binding protein REB1

1

2

High-throughput

0.470

High

760340

BMH2
Protein BMH2

1

13

High-throughput

0.470

High

806894

SET5
Histone-lysine N-methyltransferase SET5

1

2

High-throughput

0.464

High

747550

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

802359

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

874498

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

1033533

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

618888

GAP1
General amino-acid permease GAP1

1

5

Small-scale

0.457

High

481744

HSP73
Heat shock protein SSA3

1

20

High-throughput

0.445

High

524976

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

742277

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

708018

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

1042691

AEP3
ATPase expression protein 3

1

0

High-throughput

0.269

Low

827121

YIW4
Putative uncharacterized protein YIR044C

1

0

High-throughput

0.238

Low

1042689

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025