Protein: KAPCB
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)

Gene: KAPCB, PRKACB
Organism: Homo sapiens
Interactions: 171
UniProt ID: P22694

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001843 - neural tube closure
GO:0003091 - renal water homeostasis
GO:0004674 - protein serine/threonine kinase activity
GO:0004679 - AMP-activated protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

498210

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

9

20

Small-scale

0.972

High

568542

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

8

15

Small-scale

0.971

High

610686

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

8

20

High-throughput

0.971

High

533786

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

6

20

High-throughput

0.950

High

610724

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

6

16

High-throughput

0.949

High

610685

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

5

20

High-throughput

0.932

High

610751

GP161
G-protein coupled receptor 161

3

4

High-throughput

0.871

High

610798

IPKG
cAMP-dependent protein kinase inhibitor gamma

3

2

High-throughput

0.871

High

437900

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.847

High

609643

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

15

High-throughput

0.811

High

610723

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

20

High-throughput

0.811

High

431538

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.789

High

610703

IPKA
cAMP-dependent protein kinase inhibitor alpha

2

2

High-throughput

0.783

High

226534

PRKN
E3 ubiquitin-protein ligase parkin

2

14

High-throughput

0.754

High

412014

FYN
Tyrosine-protein kinase Fyn

2

17

High-throughput

0.737

High

610693

KPCI
Protein kinase C iota type

2

18

High-throughput

0.737

High

610716

KPCZ
Protein kinase C zeta type

2

18

High-throughput

0.737

High

610736

MYOME
Myomegalin

6

20

Small-scale

0.736

High

610711

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.735

High

610681

AKAP5
A-kinase anchor protein 5

5

4

High-throughput

0.725

High

610754

AKAP1
A-kinase anchor protein 1, mitochondrial

5

5

High-throughput

0.725

High

610775

AKAP9
A-kinase anchor protein 9

5

16

High-throughput

0.722

High

610790

VAPA
Vesicle-associated membrane protein-associated protein A

5

4

High-throughput

0.722

High

610791

AKA7G
A-kinase anchor protein 7 isoform gamma

5

4

High-throughput

0.722

High

610794

AKA11
A-kinase anchor protein 11

5

2

High-throughput

0.722

High

610771

CK5P2
CDK5 regulatory subunit-associated protein 2

5

20

High-throughput

0.716

High

610732

H90B4
Putative heat shock protein HSP 90-beta 4

2

20

High-throughput

0.712

High

310510

VAPB
Vesicle-associated membrane protein-associated protein B/C

4

4

High-throughput

0.699

High

610690

ACV1B
Activin receptor type-1B

1

2

High-throughput

0.698

High

229922

NUAK1
NUAK family SNF1-like kinase 1

1

15

High-throughput

0.691

High

610697

GSK3A
Glycogen synthase kinase-3 alpha

1

19

High-throughput

0.691

High

610719

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

12

High-throughput

0.691

High

610739

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

3

High-throughput

0.691

High

610767

ZN641
Zinc finger protein 641

1

1

High-throughput

0.691

High

610779

DUS16
Dual specificity protein phosphatase 16

1

2

High-throughput

0.691

High

610709

DYL1
Dynein light chain 1, cytoplasmic

3

5

High-throughput

0.675

High

610702

MLF1
Myeloid leukemia factor 1

3

2

High-throughput

0.667

High

610730

MARE1
Microtubule-associated protein RP/EB family member 1

3

2

High-throughput

0.667

High

610745

AKA28
A-kinase anchor protein 14

3

2

High-throughput

0.667

High

610762

AP2M1
AP-2 complex subunit mu

3

3

High-throughput

0.667

High

610774

SNAG
Gamma-soluble NSF attachment protein

3

1

High-throughput

0.667

High

610746

NOXA1
NADPH oxidase activator 1

1

2

Small-scale

0.647

High

610755

RYR2
Ryanodine receptor 2

1

12

Small-scale

0.647

High

559552

H12
Histone H1.2

3

2

Small-scale

0.640

High

610700

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

0

High-throughput

0.638

High

610714

RT15
Small ribosomal subunit protein uS15m

2

1

High-throughput

0.628

High

610752

RPGF5
Rap guanine nucleotide exchange factor 5

2

7

High-throughput

0.628

High

610773

NPAS1
Neuronal PAS domain-containing protein 1

2

5

High-throughput

0.628

High

384267

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.618

High

538102

ENPL
Endoplasmin

1

20

High-throughput

0.618

High

545209

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.618

High

610223

CBL
E3 ubiquitin-protein ligase CBL

1

3

High-throughput

0.618

High

610689

FUS
RNA-binding protein FUS

1

11

Small-scale

0.618

High

610698

GSK3B
Glycogen synthase kinase-3 beta

1

19

High-throughput

0.618

High

610708

RAN
GTP-binding nuclear protein Ran

1

2

Small-scale

0.618

High

610721

TADBP
TAR DNA-binding protein 43

1

13

Small-scale

0.618

High

610729

NONO
Non-POU domain-containing octamer-binding protein

1

14

Small-scale

0.618

High

610769

CCNL2
Cyclin-L2

1

3

High-throughput

0.618

High

610780

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.618

High

283098

DFFB
DNA fragmentation factor subunit beta

2

0

High-throughput

0.602

High

610692

ETFB
Electron transfer flavoprotein subunit beta

2

0

High-throughput

0.602

High

610699

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

2

0

High-throughput

0.602

High

610770

DCR1C
Protein artemis

2

0

High-throughput

0.585

High

294370

RECQ4
ATP-dependent DNA helicase Q4

2

12

Small-scale

0.584

High

359664

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

15

Small-scale

0.584

High

610742

H32
Histone H3.2

2

6

Small-scale

0.584

High

239780

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.575

High

610733

HS904
Putative heat shock protein HSP 90-alpha A4

1

20

High-throughput

0.575

High

528075

BMP1
Bone morphogenetic protein 1

2

2

High-throughput

0.574

High

610786

KLH28
Kelch-like protein 28

2

3

High-throughput

0.574

High

175823

P73
Tumor protein p73

1

2

Small-scale

0.573

High

436609

TNR16
Tumor necrosis factor receptor superfamily member 16

1

3

Small-scale

0.573

High

610753

APBP2
Amyloid protein-binding protein 2

1

2

High-throughput

0.573

High

181797

SOCS1
Suppressor of cytokine signaling 1

2

11

High-throughput

0.571

High

610740

RHG36
Rho GTPase-activating protein 36

2

3

High-throughput

0.571

High

610759

BAD
Bcl2-associated agonist of cell death

2

5

High-throughput

0.571

High

610799

PLAK2
PALM2-AKAP2 fusion protein

2

1

High-throughput

0.558

High

610735

AVPI1
Arginine vasopressin-induced protein 1

2

1

High-throughput

0.553

High

610741

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.553

High

610706

RS6
Small ribosomal subunit protein eS6

1

6

High-throughput

0.541

High

610750

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

3

High-throughput

0.541

High

175483

RA51B
DNA repair protein RAD51 homolog 2

1

2

High-throughput

0.536

High

409450

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

1

High-throughput

0.536

High

503264

MTAP2
Microtubule-associated protein 2

1

14

High-throughput

0.536

High

522538

MYH1
Myosin-1

1

12

High-throughput

0.536

High

528359

MYH6
Myosin-6

1

12

High-throughput

0.536

High

610684

COR1A
Coronin-1A

1

3

High-throughput

0.536

High

610688

TIMP3
Metalloproteinase inhibitor 3

1

1

High-throughput

0.536

High

610704

DCAF7
DDB1- and CUL4-associated factor 7

1

5

High-throughput

0.536

High

610737

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

6

High-throughput

0.536

High

610747

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.536

High

610757

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.536

High

610764

DYL2
Dynein light chain 2, cytoplasmic

1

5

High-throughput

0.536

High

610776

SMAKA
Small membrane A-kinase anchor protein

1

1

High-throughput

0.536

High

610783

PICK1
PRKCA-binding protein

1

3

High-throughput

0.536

High

610795

MYH2
Myosin-2

1

12

High-throughput

0.536

High

610802

MYH4
Myosin-4

1

12

High-throughput

0.536

High

610804

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

610695

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.518

High

610760

H2B1H
Histone H2B type 1-H

1

16

High-throughput

0.515

High

394126

A4
Amyloid-beta precursor protein

1

8

High-throughput

0.515

High

318923

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

610731

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

610748

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.513

High

610763

DDX11
ATP-dependent DNA helicase DDX11

1

0

High-throughput

0.513

High

610777

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

610787

CARF
CDKN2A-interacting protein

1

0

High-throughput

0.513

High

610792

MAP10
Microtubule-associated protein 10

1

0

High-throughput

0.513

High

610758

GPKOW
G-patch domain and KOW motifs-containing protein

1

2

Small-scale

0.506

High

449859

STP1
Spermatid nuclear transition protein 1

1

2

Small-scale

0.501

High

597959

FLNA
Filamin-A

1

3

Small-scale

0.501

High

610800

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

610701

RCAN1
Calcipressin-1

1

0

Small-scale

0.480

High

162407

XPO1
Exportin-1

1

7

High-throughput

0.479

High

182314

PER1
Period circadian protein homolog 1

1

5

High-throughput

0.479

High

215582

AKAP8
A-kinase anchor protein 8

1

3

Small-scale

0.479

High

341187

HPT
Haptoglobin

1

3

High-throughput

0.479

High

361977

FIBG
Fibrinogen gamma chain

1

2

High-throughput

0.479

High

364525

TRFE
Serotransferrin

1

4

High-throughput

0.479

High

391549

H2A1B
Histone H2A type 1-B/E

1

3

Small-scale

0.479

High

523526

XRCC6
X-ray repair cross-complementing protein 6

1

2

Small-scale

0.479

High

524793

XRCC5
X-ray repair cross-complementing protein 5

1

2

Small-scale

0.479

High

571309

DDX5
Probable ATP-dependent RNA helicase DDX5

1

8

Small-scale

0.479

High

583391

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

Small-scale

0.479

High

610682

1433T
14-3-3 protein theta

1

19

High-throughput

0.479

High

610683

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

Small-scale

0.479

High

610687

H2B1B
Histone H2B type 1-B

1

16

Small-scale

0.479

High

610694

MATR3
Matrin-3

1

4

Small-scale

0.479

High

610696

RBP2
E3 SUMO-protein ligase RanBP2

1

3

Small-scale

0.479

High

610705

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

10

Small-scale

0.479

High

610707

H4
Histone H4

1

1

Small-scale

0.479

High

610710

YBOX1
Y-box-binding protein 1

1

3

Small-scale

0.479

High

610712

H31
Histone H3.1

1

6

Small-scale

0.479

High

610713

PRKDC
DNA-dependent protein kinase catalytic subunit

1

15

Small-scale

0.479

High

610715

H33
Histone H3.3

1

6

Small-scale

0.479

High

610718

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.479

High

610720

TRAF3
TNF receptor-associated factor 3

1

6

Small-scale

0.479

High

610722

TIF1B
Transcription intermediary factor 1-beta

1

4

Small-scale

0.479

High

610738

H2A2A
Histone H2A type 2-A

1

3

Small-scale

0.479

High

610743

H2AV
Histone H2A.V

1

4

Small-scale

0.479

High

610744

MAVS
Mitochondrial antiviral-signaling protein

1

4

Small-scale

0.479

High

610749

NIN
Ninein

1

16

High-throughput

0.479

High

610756

DDX17
Probable ATP-dependent RNA helicase DDX17

1

8

Small-scale

0.479

High

610761

H2B1A
Histone H2B type 1-A

1

16

Small-scale

0.479

High

610768

H2A1A
Histone H2A type 1-A

1

3

Small-scale

0.479

High

610772

PITX2
Pituitary homeobox 2

1

5

High-throughput

0.479

High

610778

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

Small-scale

0.479

High

610784

RN216
E3 ubiquitin-protein ligase RNF216

1

2

Small-scale

0.479

High

610788

DDX56
Probable ATP-dependent RNA helicase DDX56

1

13

Small-scale

0.479

High

610789

NOP53
Ribosome biogenesis protein NOP53

1

2

Small-scale

0.479

High

610796

AKP8L
A-kinase anchor protein 8-like

1

3

Small-scale

0.479

High

610801

TRAF6
TNF receptor-associated factor 6

1

6

Small-scale

0.479

High

610803

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

14

Small-scale

0.479

High

489563

OSTP
Osteopontin

1

0

Small-scale

0.460

High

508337

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.458

High

610691

TALDO
Transaldolase

1

0

High-throughput

0.458

High

610726

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

610727

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.458

High

610728

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

Small-scale

0.458

High

610782

NHEJ1
Non-homologous end-joining factor 1

1

0

Small-scale

0.458

High

610793

TFP11
Tuftelin-interacting protein 11

1

0

Small-scale

0.458

High

610717

STP2
Nuclear transition protein 2

1

2

Small-scale

0.457

High

211293

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

4

High-throughput

0.445

High

496307

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

610725

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

610766

CEP63
Centrosomal protein of 63 kDa

1

15

High-throughput

0.445

High

610785

TRM1
tRNA

1

1

High-throughput

0.445

High

610797

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

610734

ARMX4
Armadillo repeat-containing X-linked protein 4

1

1

High-throughput

0.407

High

610765

C170L
Cep170-like protein

1

2

High-throughput

0.407

High

610781

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024