Protein: GWL
Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)

Gene: GWL, MASTL
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q96GX5

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

920192

PLK1
Serine/threonine-protein kinase PLK1

3

17

High-throughput

0.847

High

835729

KPCI
Protein kinase C iota type

1

19

High-throughput

0.691

High

1043229

TAP2
Antigen peptide transporter 2

1

1

High-throughput

0.691

High

1057643

CDK18
Cyclin-dependent kinase 18

1

13

High-throughput

0.691

High

1148377

KS6A1
Ribosomal protein S6 kinase alpha-1

1

17

High-throughput

0.691

High

1288362

TLK2
Serine/threonine-protein kinase tousled-like 2

1

19

High-throughput

0.691

High

1392521

PKHA8
Pleckstrin homology domain-containing family A member 8

1

7

High-throughput

0.691

High

955471

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

831236

CCNF
Cyclin-F

1

11

High-throughput

0.618

High

386093

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

12

High-throughput

0.584

High

231615

PRKY
Putative serine/threonine-protein kinase PRKY

1

17

High-throughput

0.575

High

553042

PIP
Prolactin-inducible protein

1

2

High-throughput

0.536

High

1213315

RM02
Large ribosomal subunit protein uL2m

1

2

High-throughput

0.536

High

1214550

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.536

High

1241566

CEP85
Centrosomal protein of 85 kDa

1

20

High-throughput

0.536

High

1392522

TCPQM
T-complex protein 1 subunit theta-like 2

1

17

High-throughput

0.536

High

1392527

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1392528

E41L5
Band 4.1-like protein 5

1

11

High-throughput

0.536

High

1392531

TELO2
Telomere length regulation protein TEL2 homolog

1

2

High-throughput

0.536

High

156070

SOCS6
Suppressor of cytokine signaling 6

1

20

High-throughput

0.515

High

336019

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.513

High

702149

ITPI2
Protein ITPRID2

1

0

High-throughput

0.513

High

1392523

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.513

High

1392529

UBN1
Ubinuclein-1

1

0

High-throughput

0.513

High

1153302

AAAT
Neutral amino acid transporter B(0)

1

1

High-throughput

0.489

High

1392526

DERL2
Derlin-2

1

1

High-throughput

0.489

High

487637

PARP1
Poly [ADP-ribose] polymerase 1

1

13

High-throughput

0.479

High

589409

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

696208

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

714350

PML
Protein PML

1

8

High-throughput

0.479

High

768889

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.479

High

807531

IF4A3
Eukaryotic initiation factor 4A-III

1

15

High-throughput

0.479

High

986629

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

991906

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.479

High

1017113

H33
Histone H3.3

1

12

High-throughput

0.479

High

1048059

TLE3
Transducin-like enhancer protein 3

1

3

High-throughput

0.479

High

1113987

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1276635

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1387486

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.479

High

1392530

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

337384

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

1097482

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1289533

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1360986

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.458

High

1392525

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

353499

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

1392524

PHAF1
Phagosome assembly factor 1

3

0

High-throughput

0.347

High

1272964

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.279

Low

1356723

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025