Protein: MAIP1
m-AAA protease-interacting protein 1, mitochondrial (Matrix AAA peptidase-interacting protein 1)

Gene: MAIP1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q8WWC4

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0032979 - protein insertion into mitochondrial inner membrane from matrix
GO:0036444 - calcium import into the mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1359197

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

422728

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

282022

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

404269

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

725630

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

1

High-throughput

0.479

High

1083684

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1359169

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1359186

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

1359188

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

1

High-throughput

0.479

High

1359205

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

1

High-throughput

0.479

High

1359208

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

156058

SOCS6
Suppressor of cytokine signaling 6

1

1

High-throughput

0.470

High

124631

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.458

High

137771

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

221621

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.458

High

275074

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

275702

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.458

High

283918

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

288980

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.458

High

298761

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.458

High

521395

ARAF
Serine/threonine-protein kinase A-Raf

1

0

High-throughput

0.458

High

560030

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

662796

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

0

High-throughput

0.458

High

766722

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

784671

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

927077

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

959220

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

1058169

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1152448

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1162197

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.458

High

1242301

SFXN4
Sideroflexin-4

1

0

High-throughput

0.458

High

1324151

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

1334694

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1359168

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.458

High

1359172

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.458

High

1359173

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.458

High

1359179

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

1359182

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

High-throughput

0.458

High

1359184

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1359187

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1359190

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1359196

TPC
Mitochondrial thiamine pyrophosphate carrier

1

0

High-throughput

0.458

High

1359198

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.458

High

1359200

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1359201

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

1359204

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.458

High

1359207

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.458

High

1359209

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

1163789

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

1

High-throughput

0.437

High

1163855

DUS6
Dual specificity protein phosphatase 6

1

1

High-throughput

0.437

High

1313769

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1352178

SSH3
Protein phosphatase Slingshot homolog 3

1

1

High-throughput

0.437

High

1359175

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.437

High

1359181

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

2

High-throughput

0.437

High

1359193

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

1359202

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1359206

PTN22
Tyrosine-protein phosphatase non-receptor type 22

1

2

High-throughput

0.437

High

1209445

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

104190

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

944012

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1359203

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

0

Small-scale

0.318

High

387593

APOC1
Apolipoprotein C-I

2

0

High-throughput

0.316

High

933979

APOC4
Apolipoprotein C-IV

2

0

High-throughput

0.316

High

1359180

H4G
Histone H4-like protein type G

2

0

High-throughput

0.316

High

962323

RHOA
Transforming protein RhoA

2

0

High-throughput

0.298

High

1359176

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.298

High

571623

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.279

Low

608315

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1142119

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1359174

HDA11
Histone deacetylase 11

1

0

High-throughput

0.279

Low

1359185

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

1359191

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1359192

S38A1
Sodium-coupled neutral amino acid symporter 1

1

0

High-throughput

0.279

Low

1157013

NTRK3
NT-3 growth factor receptor

1

0

High-throughput

0.261

Low

387627

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.251

Low

157667

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

227625

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

294095

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

315815

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

319935

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

342271

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

406433

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

463679

LYN
Tyrosine-protein kinase Lyn

1

0

Small-scale

0.249

Low

589261

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696048

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768747

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

883295

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

888208

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

947239

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

1004891

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1100170

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1140615

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1252912

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1254822

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276547

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1287069

MOB3B
MOB kinase activator 3B

1

0

High-throughput

0.249

Low

1359170

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

1359171

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.249

Low

1359177

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

Small-scale

0.249

Low

1359178

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1359189

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1359194

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1359195

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1359199

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low

841222

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

1034503

TAGL
Transgelin

1

0

High-throughput

0.232

Low

1108633

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.232

Low

1254169

MOT12
Monocarboxylate transporter 12

1

0

High-throughput

0.232

Low

1259381

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.232

Low

1323735

S39AB
Zinc transporter ZIP11

1

0

High-throughput

0.232

Low

1359183

IFT27
Intraflagellar transport protein 27 homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025