Protein: FYB1
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)

Gene: FYB1
Organism: Homo sapiens
Interactions: 37
UniProt ID: O15117

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006955 - immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

178069

FYN
Tyrosine-protein kinase Fyn

8

12

Small-scale

0.970

High

178087

LCP2
Lymphocyte cytosolic protein 2

9

9

Small-scale

0.968

High

178091

SKAP1
Src kinase-associated phosphoprotein 1

5

14

Small-scale

0.941

High

178062

NCK2
Cytoplasmic protein NCK2

3

20

Small-scale

0.827

High

178064

SKAP2
Src kinase-associated phosphoprotein 2

2

15

Small-scale

0.793

High

178072

NCK1
SH2/SH3 adapter protein NCK1

2

17

Small-scale

0.737

High

178063

SH21A
SH2 domain-containing protein 1A

1

17

Small-scale

0.713

High

178067

ABL1
Tyrosine-protein kinase ABL1

1

12

High-throughput

0.618

High

178065

GRAP2
GRB2-related adapter protein 2

1

20

Small-scale

0.575

High

178073

FER
Tyrosine-protein kinase Fer

1

13

Small-scale

0.575

High

178075

RASA1
Ras GTPase-activating protein 1

1

10

Small-scale

0.575

High

178077

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

Small-scale

0.575

High

178079

CRK
Adapter molecule crk

1

17

Small-scale

0.575

High

178080

CRKL
Crk-like protein

1

16

Small-scale

0.575

High

178084

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.575

High

178094

ARHG2
Rho guanine nucleotide exchange factor 2

1

4

Small-scale

0.575

High

178074

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

Small-scale

0.546

High

178093

DOCK2
Dedicator of cytokinesis protein 2

1

0

Small-scale

0.546

High

178090

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.515

High

178070

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

178082

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

1

Small-scale

0.501

High

178071

PYGB
Glycogen phosphorylase, brain form

1

1

High-throughput

0.489

High

178061

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

3

Small-scale

0.479

High

178068

RASN
GTPase NRas

1

14

High-throughput

0.479

High

178076

CBL
E3 ubiquitin-protein ligase CBL

1

6

Small-scale

0.479

High

178078

WASP
Actin nucleation-promoting factor WAS

1

5

Small-scale

0.479

High

178081

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

178083

VASP
Vasodilator-stimulated phosphoprotein

1

5

Small-scale

0.479

High

178085

UBC9
SUMO-conjugating enzyme UBC9

1

4

Small-scale

0.479

High

178086

KPCT
Protein kinase C theta type

1

1

Small-scale

0.479

High

178089

EEA1
Early endosome antigen 1

1

13

High-throughput

0.479

High

178095

CAR11
Caspase recruitment domain-containing protein 11

1

6

Small-scale

0.479

High

178097

XPO7
Exportin-7

1

2

High-throughput

0.479

High

178066

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.458

High

178088

CKAP5
Cytoskeleton-associated protein 5

1

2

Small-scale

0.445

High

178096

EVL
Ena/VASP-like protein

1

5

Small-scale

0.445

High

178092

SELH
Selenoprotein H

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025