Protein: VMA12
Vacuolar ATPase assembly protein VMA12 (Transmembrane protein 199)

Gene: VMA12
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q8N511

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0007042 - lysosomal lumen acidification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292690

RENR
Renin receptor

4

1

High-throughput

0.691

High

1327076

VPP2
V-type proton ATPase 116 kDa subunit a 2

4

6

High-throughput

0.691

High

1327033

VPP1
V-type proton ATPase 116 kDa subunit a 1

3

6

High-throughput

0.662

High

1087187

STX4
Syntaxin-4

3

2

High-throughput

0.653

High

375720

RASK
GTPase KRas

3

3

High-throughput

0.640

High

961542

VA0D1
V-type proton ATPase subunit d 1

2

2

High-throughput

0.611

High

1327022

VA0D2
V-type proton ATPase subunit d 2

2

2

High-throughput

0.611

High

1159601

STX1A
Syntaxin-1A

2

2

High-throughput

0.606

High

1327049

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.606

High

1327053

REEP4
Receptor expression-enhancing protein 4

2

1

High-throughput

0.606

High

692233

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.602

High

1191775

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.602

High

1197252

MBRL
Membralin

2

0

High-throughput

0.602

High

1219299

ECM29
Proteasome adapter and scaffold protein ECM29

2

0

High-throughput

0.602

High

1327041

VMA22
Vacuolar ATPase assembly protein VMA22

2

0

High-throughput

0.602

High

1106795

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

6

High-throughput

0.601

High

1327055

VPP4
V-type proton ATPase 116 kDa subunit a 4

2

6

High-throughput

0.601

High

540561

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

800302

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.580

High

1102413

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.580

High

1142879

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1327020

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

951260

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

283304

ERLN1
Erlin-1

1

0

High-throughput

0.549

High

1164253

VATF
V-type proton ATPase subunit F

1

1

High-throughput

0.536

High

385963

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

1

High-throughput

0.535

High

1180930

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.513

High

1327035

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1327065

TM63C
Osmosensitive cation channel TMEM63C

1

0

High-throughput

0.513

High

1327031

CLC2B
C-type lectin domain family 2 member B

1

1

High-throughput

0.489

High

1327077

PCDG5
Protocadherin gamma-A5

1

1

High-throughput

0.489

High

1327078

PCDA8
Protocadherin alpha-8

1

1

High-throughput

0.489

High

48697

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

189703

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

466354

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.479

High

562225

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

604094

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

631341

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

715673

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

900920

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

901938

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

953562

RAC3
Ras-related C3 botulinum toxin substrate 3

1

4

High-throughput

0.479

High

955372

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.479

High

956389

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

962266

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

1015594

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.479

High

1027081

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

1327034

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1327040

DNJC1
DnaJ homolog subfamily C member 1

1

2

High-throughput

0.479

High

1327043

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1327045

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1327050

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1327062

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1327068

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.479

High

1327075

GOT1B
Vesicle transport protein GOT1B

1

1

High-throughput

0.479

High

173991

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

417575

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418265

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

548351

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

611225

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

698878

CALX
Calnexin

1

0

High-throughput

0.458

High

847599

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

880608

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

894894

EMD
Emerin

1

0

High-throughput

0.458

High

904005

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1058523

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1111606

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1125538

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1204872

MKS3
Meckelin

1

0

High-throughput

0.458

High

1327023

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1327024

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

1327026

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1327028

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.458

High

1327036

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1327042

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1327044

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1327046

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1327048

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1327051

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1327054

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1327063

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

1327066

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1327074

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.458

High

188936

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

556214

CADH1
Cadherin-1

1

1

High-throughput

0.437

High

630572

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

630882

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.437

High

634526

LMNB1
Lamin-B1

1

1

High-throughput

0.437

High

910129

RND2
Rho-related GTP-binding protein RhoN

1

5

High-throughput

0.437

High

1145012

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

1238736

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1286830

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1322890

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1327030

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1327039

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1327059

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1327070

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

1327072

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

627373

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

1

High-throughput

0.407

High

1153412

CD226
CD226 antigen

1

1

High-throughput

0.407

High

1327038

TSN17
Tetraspanin-17

3

0

High-throughput

0.347

High

186477

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.328

High

922466

CLH2
Clathrin heavy chain 2

2

0

High-throughput

0.328

High

1249619

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

1108962

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1327037

NTCP4
Sodium/bile acid cotransporter 4

2

0

High-throughput

0.316

High

1327056

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.316

High

1327060

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1327067

CLM8
CMRF35-like molecule 8

2

0

High-throughput

0.316

High

1315447

K2013
Uncharacterized protein KIAA2013

2

0

High-throughput

0.313

High

1327021

KASH5
Protein KASH5

1

0

High-throughput

0.299

High

835490

CCR2
C-C chemokine receptor type 2

1

0

High-throughput

0.282

High

590310

MUC1
Mucin-1

1

0

High-throughput

0.279

Low

1125862

FZD2
Frizzled-2

1

0

High-throughput

0.279

Low

1327027

T185A
Transmembrane protein 185A

1

0

High-throughput

0.279

Low

1327069

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

519163

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

820688

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.249

Low

837717

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

845723

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

939387

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.249

Low

975126

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low

976411

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

1004129

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.249

Low

1163374

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1288479

LBN
Limbin

1

0

High-throughput

0.249

Low

1293069

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1293612

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1326989

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.249

Low

1327025

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.249

Low

1327032

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1327052

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1327057

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

1327058

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1327061

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1327064

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1327071

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.249

Low

1244100

TMM88
Transmembrane protein 88

1

0

High-throughput

0.232

Low

1253588

SO4C1
Solute carrier organic anion transporter family member 4C1

1

0

High-throughput

0.232

Low

1327029

MOT10
Monocarboxylate transporter 10

1

0

High-throughput

0.232

Low

1327047

S19A3
Thiamine transporter 2

1

0

High-throughput

0.232

Low

1327073

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025