Protein: SACS
Sacsin (DnaJ homolog subfamily C member 29)

Gene: SACS
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q9NZJ4

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006457 - protein folding
GO:0030424 - axon

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335713

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

2

0

High-throughput

0.770

High

1453344

SACS
Sacsin

1

0

Small-scale

0.693

High

249208

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.663

High

920318

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.656

High

1116067

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.656

High

1453349

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.656

High

1050555

UBE3A
Ubiquitin-protein ligase E3A

1

0

Small-scale

0.614

High

243152

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.586

High

1114489

CUL3
Cullin-3

1

0

High-throughput

0.586

High

1255859

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.586

High

1101687

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

1

High-throughput

0.549

High

1382395

SPSB4
SPRY domain-containing SOCS box protein 4

2

1

High-throughput

0.549

High

1022978

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

458500

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

1453348

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.518

High

1337383

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.517

High

262324

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.514

High

390200

ALBU
Albumin

1

0

High-throughput

0.513

High

486631

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

729483

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

0

High-throughput

0.513

High

1432531

P63
Tumor protein 63

1

0

Small-scale

0.513

High

361366

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

1096410

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

0

High-throughput

0.493

High

224814

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.486

High

1448372

PICK1
PRKCA-binding protein

1

0

High-throughput

0.486

High

1048396

ACVR1
Activin receptor type-1

1

0

High-throughput

0.481

High

1293924

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.481

High

968007

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

Small-scale

0.480

High

475030

VIME
Vimentin

1

1

High-throughput

0.479

High

487829

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

833378

PERI
Peripherin

1

1

High-throughput

0.479

High

259147

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

589893

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

681536

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

696712

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

791782

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

840814

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

905216

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

1106100

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1276885

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1293684

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1369583

ATOH1
Transcription factor ATOH1

1

0

Small-scale

0.458

High

1405888

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.458

High

1430608

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1434084

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1451862

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

1453346

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.458

High

914494

EFNB2
Ephrin-B2

1

1

High-throughput

0.445

High

1448503

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

344345

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

373342

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.426

High

1248847

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

3

0

High-throughput

0.347

High

1453345

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.282

High

1120978

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1453347

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

191410

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.269

Low

1141979

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low

1439690

MYO10
Unconventional myosin-X

1

0

Small-scale

0.249

Low

1450005

LMBD1
Lysosomal cobalamin transport escort protein LMBD1

1

0

High-throughput

0.249

Low

388321

GLPA
Glycophorin-A

1

0

High-throughput

0.232

Low

683354

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

760779

CD68
Macrosialin

1

0

High-throughput

0.232

Low

1187585

AR13B
ADP-ribosylation factor-like protein 13B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025