Protein: PRP4
U4/U6 small nuclear ribonucleoprotein PRP4 (Pre-mRNA-processing protein 4)

Gene: PRP4
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P20053

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000393 - spliceosomal conformational changes to generate catalytic conformation
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

589096

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

7

4

Small-scale

0.972

High

589070

PRP8
Pre-mRNA-splicing factor 8

4

4

Small-scale

0.892

High

589073

SN114
Pre-mRNA-splicing factor SNU114

3

6

High-throughput

0.855

High

589069

BRR2
Pre-mRNA-splicing helicase BRR2

9

17

Small-scale

0.750

High

586357

PRP6
Pre-mRNA-splicing factor 6

6

18

Small-scale

0.732

High

589085

LSM8
U6 snRNA-associated Sm-like protein LSm8

5

15

Small-scale

0.715

High

589091

LSM3
U6 snRNA-associated Sm-like protein LSm3

5

20

Small-scale

0.706

High

589089

LSM7
U6 snRNA-associated Sm-like protein LSm7

4

15

High-throughput

0.697

High

589086

PRP31
Pre-mRNA-processing factor 31

4

8

High-throughput

0.694

High

589078

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

6

High-throughput

0.691

High

589111

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

4

Small-scale

0.691

High

589090

RUXF
Small nuclear ribonucleoprotein F

4

6

High-throughput

0.683

High

589066

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

10

High-throughput

0.679

High

589077

SNU13
13 kDa ribonucleoprotein-associated protein

1

10

High-throughput

0.665

High

589075

LSM2
U6 snRNA-associated Sm-like protein LSm2

3

17

High-throughput

0.662

High

589081

RUXG
Small nuclear ribonucleoprotein G

3

11

High-throughput

0.643

High

589109

RUXE
Small nuclear ribonucleoprotein E

3

3

High-throughput

0.643

High

589076

SP381
Pre-mRNA-splicing factor SPP381

3

0

High-throughput

0.634

High

589110

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

3

0

High-throughput

0.634

High

548507

GCN2
eIF-2-alpha kinase GCN2

2

3

High-throughput

0.621

High

589080

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

2

High-throughput

0.621

High

589098

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

6

High-throughput

0.621

High

549699

STI1
Heat shock protein STI1

1

16

High-throughput

0.618

High

589065

ARP2
Actin-related protein 2

1

7

High-throughput

0.618

High

589079

LSM4
U6 snRNA-associated Sm-like protein LSm4

2

7

High-throughput

0.611

High

589097

SMD2
Small nuclear ribonucleoprotein Sm D2

2

3

High-throughput

0.601

High

589095

UTP17
NET1-associated nuclear protein 1

1

13

High-throughput

0.595

High

589099

RRP9
Ribosomal RNA-processing protein 9

1

19

High-throughput

0.595

High

589082

SMD3
Small nuclear ribonucleoprotein Sm D3

2

17

Small-scale

0.584

High

490301

HSP71
Heat shock protein SSA1

2

17

Small-scale

0.571

High

589067

PRP19
Pre-mRNA-processing factor 19

2

16

Small-scale

0.571

High

589064

XPO1
Exportin-1

1

10

High-throughput

0.536

High

589068

PRP21
Pre-mRNA-splicing factor PRP21

1

3

High-throughput

0.536

High

589056

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

11

High-throughput

0.515

High

589071

LHP1
La protein homolog

1

7

High-throughput

0.515

High

589084

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

5

High-throughput

0.515

High

589093

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.515

High

589105

SAS10
Something about silencing protein 10

1

1

High-throughput

0.515

High

589112

NOP56
Nucleolar protein 56

1

8

High-throughput

0.515

High

365770

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.500

High

554547

HSP26
Heat shock protein 26

1

4

High-throughput

0.500

High

589060

CDC48
Cell division control protein 48

1

6

High-throughput

0.500

High

410901

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

589062

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

589063

BMH1
Protein BMH1

1

4

High-throughput

0.479

High

589094

SMD1
Small nuclear ribonucleoprotein Sm D1

1

2

High-throughput

0.479

High

589100

DIB1
Spliceosomal protein DIB1

1

2

High-throughput

0.479

High

589102

NCBP2
Nuclear cap-binding protein subunit 2

1

4

High-throughput

0.479

High

589103

RU2A
U2 small nuclear ribonucleoprotein A'

1

14

High-throughput

0.479

High

589106

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

589107

YRA1
RNA annealing protein YRA1

1

7

High-throughput

0.479

High

549324

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.470

High

589114

NOP58
Nucleolar protein 58

1

8

High-throughput

0.470

High

589074

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

589092

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

341915

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.457

High

342656

ENO1
Enolase 1

1

2

High-throughput

0.457

High

378280

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

540022

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.457

High

587920

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.457

High

589057

CLH
Clathrin heavy chain

1

6

High-throughput

0.457

High

589058

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.457

High

589072

MDJ1
DnaJ homolog 1, mitochondrial

1

4

High-throughput

0.457

High

589108

HSP42
Heat shock protein 42

1

5

High-throughput

0.457

High

392284

H2A2
Histone H2A.2

1

5

High-throughput

0.445

High

510221

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

589059

MSH3
DNA mismatch repair protein MSH3

1

1

High-throughput

0.445

High

543170

HSC82
ATP-dependent molecular chaperone HSC82

1

11

High-throughput

0.437

High

589104

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

2

High-throughput

0.437

High

589083

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.407

High

589061

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.269

Low

589087

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.269

Low

589101

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.269

Low

589113

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.269

Low

404300

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.261

Low

589088

FOL1
Folic acid synthesis protein FOL1 [Includes: Dihydroneopterin aldolase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024