Protein: PYRH
Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK)

Gene: PYRH
Organism: Escherichia coli K-12
Interactions: 56
UniProt ID: P0A7E9

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006221 - pyrimidine nucleotide biosynthetic process
GO:0006225 - UDP biosynthetic process
GO:0033862 - UMP kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

489492

CH60
Chaperonin GroEL

2

1

High-throughput

0.588

High

490499

EFG
Elongation factor G

2

1

High-throughput

0.588

High

492221

RS10
Small ribosomal subunit protein uS10

2

2

High-throughput

0.588

High

492230

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

1

High-throughput

0.588

High

492213

RECA
Protein RecA

2

0

High-throughput

0.563

High

492217

RL1
Large ribosomal subunit protein uL1

2

0

High-throughput

0.563

High

492224

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.563

High

492243

YHBY
RNA-binding protein YhbY

2

0

High-throughput

0.563

High

492250

PTKB
PTS system galactitol-specific EIIB component

2

0

High-throughput

0.563

High

492253

RL2
Large ribosomal subunit protein uL2

2

0

High-throughput

0.563

High

492258

PTKA
PTS system galactitol-specific EIIA component

2

0

High-throughput

0.563

High

492249

THIE
Thiamine-phosphate synthase

2

1

High-throughput

0.537

High

490547

EFTS
Elongation factor Ts

1

0

High-throughput

0.513

High

492235

YIEE
Uncharacterized protein YieE

1

0

High-throughput

0.513

High

492231

DEOD
Purine nucleoside phosphorylase DeoD-type

1

0

High-throughput

0.493

High

490997

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.484

High

492232

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.484

High

492233

DBHB
DNA-binding protein HU-beta

1

1

High-throughput

0.484

High

382637

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.464

High

473245

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.464

High

492214

RL11
Large ribosomal subunit protein uL11

1

0

High-throughput

0.464

High

492215

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.464

High

492216

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

492219

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.464

High

492220

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

492225

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.464

High

492226

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.464

High

492227

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

492234

HNS
DNA-binding protein H-NS

1

0

High-throughput

0.464

High

492238

RHO
Transcription termination factor Rho

1

0

High-throughput

0.464

High

492239

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

492242

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

492244

RL18
Large ribosomal subunit protein uL18

1

0

High-throughput

0.464

High

492248

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.464

High

492254

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.464

High

492255

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

492256

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

492257

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.464

High

382547

RS6
Small ribosomal subunit protein bS6

1

0

High-throughput

0.458

High

492228

THIO
Thioredoxin 1

1

0

Small-scale

0.426

High

491755

LPXC
UDP-3-O-acyl-N-acetylglucosamine deacetylase

2

0

High-throughput

0.307

High

492222

RS16
Small ribosomal subunit protein bS16

2

0

High-throughput

0.307

High

492229

CADB
Cadaverine/lysine antiporter

2

0

High-throughput

0.307

High

492236

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.307

High

492237

USPA
Universal stress protein A

2

0

High-throughput

0.307

High

492241

RS1
Small ribosomal subunit protein bS1

2

0

High-throughput

0.307

High

492245

DEGP
Periplasmic serine endoprotease DegP

2

0

High-throughput

0.307

High

492259

LETB
Lipophilic envelope-spanning tunnel protein B

2

0

High-throughput

0.307

High

492260

FLXA
Protein FlxA

1

0

High-throughput

0.282

High

492251

IAAA
Isoaspartyl peptidase

1

0

High-throughput

0.279

Low

492218

RL27
Large ribosomal subunit protein bL27

1

0

High-throughput

0.253

Low

492223

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.253

Low

492246

GATZ
D-tagatose-1,6-bisphosphate aldolase subunit GatZ

1

0

High-throughput

0.253

Low

492247

EFTU1
Elongation factor Tu 1

1

0

High-throughput

0.253

Low

492252

USPG
Universal stress protein UP12

1

0

High-throughput

0.253

Low

492240

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025