Protein: DCP1
mRNA-decapping enzyme subunit 1

Gene: DCP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: Q12517

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921144

DCP2
m7GpppN-mRNA hydrolase

12

1

Small-scale

0.981

High

916982

EDC1
Enhancer of mRNA-decapping protein 1

2

0

Small-scale

0.728

High

816675

EDC3
Enhancer of mRNA-decapping protein 3

7

0

Small-scale

0.714

High

721679

RENT1
ATP-dependent helicase NAM7

6

0

Small-scale

0.698

High

812143

DHH1
ATP-dependent RNA helicase DHH1

6

0

Small-scale

0.696

High

796741

TTL
Probable tubulin--tyrosine ligase PBY1

4

0

Small-scale

0.668

High

709497

HRR25
Casein kinase I homolog HRR25

4

0

Small-scale

0.666

High

817254

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.663

High

1042847

EBS1
Nonsense-mediated mRNA decay factor EBS1

4

0

Small-scale

0.656

High

678770

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

4

0

Small-scale

0.651

High

853612

SCD6
Protein SCD6

4

0

Small-scale

0.649

High

818076

LSM4
LSM complex subunit LSM4

3

0

Small-scale

0.638

High

645575

XRN1
5'-3' exoribonuclease 1

3

0

Small-scale

0.630

High

722386

XPO1
Exportin-1

2

0

High-throughput

0.606

High

864150

LSM1
LSM1-LSM7 complex subunit LSM1

2

3

Small-scale

0.601

High

945367

LSM3
LSM complex subunit LSM3

2

3

Small-scale

0.601

High

795953

LSM2
LSM complex subunit LSM2

2

1

Small-scale

0.600

High

503531

RS28B
Small ribosomal subunit protein eS28B

3

1

Small-scale

0.591

High

818500

LSM5
LSM complex subunit LSM5

2

0

Small-scale

0.576

High

525667

HSP71
Heat shock protein SSA1

2

1

Small-scale

0.571

High

528115

HSP72
Heat shock protein SSA2

2

1

Small-scale

0.571

High

1085027

RS28A
Small ribosomal subunit protein eS28A

2

1

High-throughput

0.566

High

403715

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.537

High

806395

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.529

High

430953

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.515

High

924570

LSM7
LSM complex subunit LSM7

1

2

Small-scale

0.515

High

923163

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

865296

LSM8
LSM2-LSM8 complex subunit LSM8

1

3

High-throughput

0.508

High

623984

MYO2
Myosin-2

1

0

Small-scale

0.504

High

809070

POP2
Poly(A) ribonuclease POP2

1

0

Small-scale

0.493

High

1054953

LSM6
LSM complex subunit LSM6

1

0

Small-scale

0.493

High

743431

TOR2
Serine/threonine-protein kinase TOR2

1

1

High-throughput

0.481

High

762886

TOR1
Serine/threonine-protein kinase TOR1

1

1

High-throughput

0.481

High

676783

GBP2
Serine/arginine

1

2

Small-scale

0.479

High

807703

HRB1
Serine/arginine

1

1

Small-scale

0.479

High

809472

MPT5
Suppressor protein MPT5

1

1

Small-scale

0.479

High

1060076

PUF3
mRNA-binding protein PUF3

1

1

Small-scale

0.479

High

435456

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436245

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

442187

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

580305

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

674910

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

727432

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

778605

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

792326

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

815290

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

918505

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

924790

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.458

High

1033646

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1044864

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1084347

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

742760

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

863193

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.438

High

1054935

NCS1
Calcium-binding protein NCS-1

1

0

High-throughput

0.438

High

386931

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

395041

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

546887

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

592605

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

671751

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

912475

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

1038007

NU116
Nucleoporin NUP116/NSP116

1

0

High-throughput

0.282

High

410411

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

504489

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513296

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

747657

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753666

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

812796

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

824821

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

1084388

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025