Protein: URE2
Transcriptional regulator URE2 (Disulfide reductase) (EC 1.8.4.-) (Glutathione peroxidase) (EC 1.11.1.9)

Gene: URE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P23202

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0004364 - glutathione transferase activity
GO:0004602 - glutathione peroxidase activity
GO:0005737 - cytoplasm
GO:0006808 - regulation of nitrogen utilization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654756

URE2
Transcriptional regulator URE2

17

14

Small-scale

0.988

High

615001

GLN3
Nitrogen regulatory protein GLN3

9

4

Small-scale

0.755

High

523098

HSP71
Heat shock protein SSA1

4

1

Small-scale

0.698

High

654777

TOR1
Serine/threonine-protein kinase TOR1

2

1

Small-scale

0.619

High

654789

GAT1
Transcriptional regulatory protein GAT1

2

4

High-throughput

0.613

High

654778

NNK1
Nitrogen network kinase 1

2

0

High-throughput

0.606

High

654774

TOR2
Serine/threonine-protein kinase TOR2

2

1

Small-scale

0.595

High

654793

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

1

Small-scale

0.561

High

654757

STE11
Serine/threonine-protein kinase STE11

1

1

High-throughput

0.541

High

642323

MCK1
Protein kinase MCK1

1

1

High-throughput

0.536

High

416861

CDC25
Cell division control protein 25

1

0

High-throughput

0.518

High

559658

GAL3
Protein GAL3

1

0

High-throughput

0.518

High

654764

BUD14
Bud site selection protein 14

1

0

High-throughput

0.518

High

654776

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.518

High

654802

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.518

High

654803

GRH1
GRASP65 homolog protein 1

1

0

High-throughput

0.518

High

654768

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

654769

XPO1
Exportin-1

1

0

High-throughput

0.513

High

654763

DAL80
Nitrogen regulatory protein DAL80

1

4

High-throughput

0.508

High

392254

HSP82
ATP-dependent molecular chaperone HSP82

1

3

Small-scale

0.501

High

577527

CYC8
General transcriptional corepressor CYC8

1

3

Small-scale

0.501

High

654762

TAH1
TPR repeat-containing protein associated with Hsp90

1

4

Small-scale

0.501

High

357724

CYC7
Cytochrome c isoform 2

1

2

High-throughput

0.494

High

654786

PTPA1
Serine/threonine-protein phosphatase 2A activator 1

1

0

High-throughput

0.486

High

654792

BIT61
Target of rapamycin complex 2 subunit BIT61

1

0

High-throughput

0.486

High

654800

MUK1
Protein MUK1

1

0

High-throughput

0.486

High

654782

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.481

High

598374

TUP1
General transcriptional corepressor TUP1

1

0

Small-scale

0.480

High

654761

MAS5
Mitochondrial protein import protein MAS5

1

0

Small-scale

0.480

High

654770

HS104
Heat shock protein 104

1

0

Small-scale

0.480

High

525957

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.479

High

578875

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

654797

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.479

High

654785

PSA6
Proteasome subunit alpha type-6

1

6

High-throughput

0.464

High

654804

STE23
A-factor-processing enzyme

1

2

High-throughput

0.464

High

654758

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

654773

DUR1
Urea amidolyase [Includes: Urea carboxylase

1

0

High-throughput

0.458

High

654779

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.458

High

654791

RSF2
Respiration factor 2

1

0

High-throughput

0.458

High

654794

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.458

High

654796

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

654759

SIS1
Protein SIS1

1

1

Small-scale

0.457

High

654798

RAGAB
GTP-binding protein GTR1

1

1

High-throughput

0.457

High

654788

GZF3
Protein GZF3

1

4

Small-scale

0.439

High

654807

YB21A
Transposon Ty2-B Gag polyprotein

1

0

High-throughput

0.438

High

654784

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

654787

FKH1
Fork head protein homolog 1

2

0

Small-scale

0.320

High

654775

YEF1
ATP-NADH kinase YEF1

1

0

High-throughput

0.282

High

654795

HFM1
ATP-dependent DNA helicase MER3

1

0

High-throughput

0.282

High

654808

GPR1
G protein-coupled receptor GPR1

1

0

High-throughput

0.282

High

459026

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.279

Low

575387

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.269

Low

654809

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.269

Low

603010

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.265

Low

654765

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.265

Low

654766

YJU2
Splicing factor YJU2

1

0

High-throughput

0.265

Low

654772

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.265

Low

654801

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.265

Low

654805

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.265

Low

555229

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.249

Low

646632

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.249

Low

654760

AGP1
General amino acid permease AGP1

1

0

High-throughput

0.249

Low

654767

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

654771

DGR2
2-deoxy-glucose resistant protein 2

1

0

High-throughput

0.249

Low

654780

QDR3
Quinidine resistance protein 3

1

0

High-throughput

0.249

Low

654781

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

654783

FIR1
Factor interacting with REF2

1

0

High-throughput

0.249

Low

654790

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.249

Low

654799

CTF4
DNA polymerase alpha-binding protein

1

0

High-throughput

0.249

Low

654806

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025