Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1
Interactor 2: LIMK1 (P53667)
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
Gene: LIMK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32015554, 23082153, 12963706, 23093407, 10436159, 27153537, 15220930, 16278681, 17500066, 20133759, 19424295, 17853892 |
| Identification Methods | affinity chromatography technology, enzymatic study, x-ray crystallography, anti bait coimmunoprecipitation, protein kinase assay |
| Interaction Type | physical association, direct interaction, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cofilin_ADF~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007266 - Rho protein signal transduction and 3 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
