Protein: P52K
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12)

Gene: P52K, THAP12
Organism: Homo sapiens
Interactions: 110
UniProt ID: O43422

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0007165 - signal transduction
GO:0008270 - zinc ion binding
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

215775

ROA1
Heterogeneous nuclear ribonucleoprotein A1

3

2

High-throughput

0.667

High

215847

LHX4
LIM/homeobox protein Lhx4

3

2

High-throughput

0.667

High

215841

ZN526
Zinc finger protein 526

3

4

High-throughput

0.665

High

215831

ZN574
Zinc finger protein 574

3

4

High-throughput

0.662

High

215763

TACC1
Transforming acidic coiled-coil-containing protein 1

3

0

High-throughput

0.646

High

215812

STK4
Serine/threonine-protein kinase 4

2

3

Small-scale

0.639

High

215785

SMBP2
DNA-binding protein SMUBP-2

2

1

High-throughput

0.628

High

215843

ASB10
Ankyrin repeat and SOCS box protein 10

2

2

High-throughput

0.628

High

215762

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

11

Small-scale

0.618

High

215782

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.601

High

215815

DNJC3
DnaJ homolog subfamily C member 3

2

8

Small-scale

0.594

High

215780

RS2
Small ribosomal subunit protein uS5

2

0

High-throughput

0.585

High

215766

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.576

High

215801

PRR3
Proline-rich protein 3

2

0

High-throughput

0.576

High

215840

GP156
Probable G-protein coupled receptor 156

2

1

High-throughput

0.574

High

215858

CCG5
Voltage-dependent calcium channel gamma-5 subunit

2

2

High-throughput

0.574

High

215771

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

215839

K1958
Uncharacterized protein KIAA1958

2

1

High-throughput

0.553

High

215824

MAPK3
MAP kinase-activated protein kinase 3

1

1

Small-scale

0.552

High

215790

RS10
Small ribosomal subunit protein eS10

2

1

High-throughput

0.549

High

215819

KRR1
KRR1 small subunit processome component homolog

2

1

High-throughput

0.549

High

215854

XAGE1
X antigen family member 1

2

1

High-throughput

0.549

High

215764

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

3

High-throughput

0.536

High

215768

LDOC1
Protein LDOC1

1

3

High-throughput

0.536

High

215773

H2A1B
Histone H2A type 1-B/E

1

4

High-throughput

0.536

High

215774

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.536

High

215776

H2A1
Histone H2A type 1

1

4

High-throughput

0.536

High

215778

GLI4
Zinc finger protein GLI4

1

6

High-throughput

0.536

High

215779

H14
Histone H1.4

1

3

High-throughput

0.536

High

215783

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

215788

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.536

High

215809

NOTC2
Neurogenic locus notch homolog protein 2

1

2

High-throughput

0.536

High

215810

SRSF1
Serine/arginine-rich splicing factor 1

1

8

High-throughput

0.536

High

215811

SRSF4
Serine/arginine-rich splicing factor 4

1

5

High-throughput

0.536

High

215814

STK3
Serine/threonine-protein kinase 3

1

3

High-throughput

0.536

High

215823

SRSF7
Serine/arginine-rich splicing factor 7

1

5

High-throughput

0.536

High

215825

H2A2C
Histone H2A type 2-C

1

4

High-throughput

0.536

High

215827

RN151
RING finger protein 151

1

9

High-throughput

0.536

High

215834

ZN467
Zinc finger protein 467

1

2

High-throughput

0.536

High

215846

FGF13
Fibroblast growth factor 13

1

3

High-throughput

0.536

High

215849

ZN668
Zinc finger protein 668

1

2

High-throughput

0.536

High

215853

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.536

High

215856

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

2

High-throughput

0.536

High

215861

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

215862

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

215864

YBOX2
Y-box-binding protein 2

1

3

High-throughput

0.536

High

215796

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

215797

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

215822

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

215836

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

215848

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

215860

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

215772

P53
Cellular tumor antigen p53

1

2

Small-scale

0.501

High

215829

H2B2F
Histone H2B type 2-F

1

0

High-throughput

0.493

High

215794

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.489

High

215799

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.489

High

215806

SRSF3
Serine/arginine-rich splicing factor 3

1

6

High-throughput

0.489

High

215817

SRSF5
Serine/arginine-rich splicing factor 5

1

7

High-throughput

0.489

High

215818

SRSF6
Serine/arginine-rich splicing factor 6

1

6

High-throughput

0.489

High

215821

K1H2
Keratin, type I cuticular Ha2

1

5

High-throughput

0.489

High

215865

RT02
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.489

High

215866

TMED5
Transmembrane emp24 domain-containing protein 5

1

1

High-throughput

0.489

High

215769

RIGI
Antiviral innate immune response receptor RIG-I

1

0

Small-scale

0.480

High

215777

H2AB2
Histone H2A-Bbd type 2/3

1

5

High-throughput

0.479

High

215791

MAPK2
MAP kinase-activated protein kinase 2

1

1

Small-scale

0.479

High

215800

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

215808

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.479

High

215820

CUL3
Cullin-3

1

1

High-throughput

0.479

High

215830

Q6ICH2
single-stranded DNA cytosine deaminase

1

2

High-throughput

0.479

High

215832

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

215838

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

215845

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

215851

SH3G2
Endophilin-A1

1

2

High-throughput

0.479

High

215859

XPO7
Exportin-7

1

4

High-throughput

0.479

High

215767

CCN5
CCN family member 5

1

0

High-throughput

0.458

High

215781

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

0

Small-scale

0.458

High

215784

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

215787

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

215793

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

215850

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.458

High

47472

RPSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.445

High

73354

B2CML4
single-stranded DNA cytosine deaminase

1

2

High-throughput

0.445

High

191487

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.445

High

215807

AK17A
A-kinase anchor protein 17A

1

1

High-throughput

0.445

High

215852

ZN692
Zinc finger protein 692

1

9

High-throughput

0.445

High

104887

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

215770

IGHM
Immunoglobulin heavy constant mu

1

1

High-throughput

0.407

High

215833

RIC3
Protein RIC-3

1

1

High-throughput

0.407

High

215813

FADD
FAS-associated death domain protein

3

0

High-throughput

0.347

High

215842

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

215795

RS14
Small ribosomal subunit protein uS11

2

0

High-throughput

0.328

High

215786

RS19
Small ribosomal subunit protein eS19

2

0

High-throughput

0.313

High

215805

RL19
Large ribosomal subunit protein eL19

2

0

High-throughput

0.313

High

215765

NPM3
Nucleoplasmin-3

1

0

High-throughput

0.279

Low

215789

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.279

Low

215792

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.279

Low

215802

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.279

Low

215803

RT15
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.279

Low

215804

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.279

Low

215826

SKDA1
SKI/DACH domain-containing protein 1

1

0

High-throughput

0.279

Low

215828

LRC73
Leucine-rich repeat-containing protein 73

1

0

High-throughput

0.279

Low

215835

CDR2L
Cerebellar degeneration-related protein 2-like

1

0

High-throughput

0.279

Low

215837

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

215844

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.279

Low

215857

TNR19
Tumor necrosis factor receptor superfamily member 19

1

0

High-throughput

0.279

Low

215863

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

215816

SBP1
Methanethiol oxidase

1

0

High-throughput

0.268

Low

215855

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

215798

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025