Protein: SLX4I
Protein SLX4IP (SLX4-interacting protein)

Gene: SLX4I, SLX4IP
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q5VYV7

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1219454

SLX4
Structure-specific endonuclease subunit SLX4

6

1

Small-scale

0.670

High

270559

LRP4
Low-density lipoprotein receptor-related protein 4

1

1

Small-scale

0.437

High

558197

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.437

High

559381

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.437

High

799205

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.437

High

833966

HNF4A
Hepatocyte nuclear factor 4-alpha

1

1

High-throughput

0.437

High

928473

TERF1
Telomeric repeat-binding factor 1

1

1

Small-scale

0.437

High

1088872

TP53B
TP53-binding protein 1

1

1

High-throughput

0.437

High

1129621

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.437

High

1149903

TERF2
Telomeric repeat-binding factor 2

1

1

Small-scale

0.437

High

1219457

SORL
Sortilin-related receptor

1

1

Small-scale

0.437

High

1219458

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1219462

MAP6
Microtubule-associated protein 6

1

1

Small-scale

0.437

High

328044

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

1

High-throughput

0.407

High

1219474

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.407

High

1158115

MK14
Mitogen-activated protein kinase 14

4

0

High-throughput

0.360

High

484566

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

3

0

High-throughput

0.347

High

561125

GILT
Gamma-interferon-inducible lysosomal thiol reductase

3

0

High-throughput

0.347

High

1219469

PDD2L
Programmed cell death protein 2-like

3

0

High-throughput

0.347

High

464381

ERCC1
DNA excision repair protein ERCC-1

3

0

Small-scale

0.342

High

920031

PLK1
Serine/threonine-protein kinase PLK1

2

0

High-throughput

0.328

High

1219467

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

1219459

XPF
DNA repair endonuclease XPF

2

0

Small-scale

0.318

High

1219461

AJUBA
LIM domain-containing protein ajuba

2

0

Small-scale

0.318

High

964321

SUMO2
Small ubiquitin-related modifier 2

2

0

Small-scale

0.314

High

714187

PML
Protein PML

2

0

High-throughput

0.305

High

300378

KRT34
Keratin, type I cuticular Ha4

1

0

High-throughput

0.279

Low

417494

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.279

Low

945581

FBXW4
F-box/WD repeat-containing protein 4

1

0

High-throughput

0.279

Low

1093122

STK4
Serine/threonine-protein kinase 4

1

0

High-throughput

0.279

Low

1112544

CUL1
Cullin-1

1

0

High-throughput

0.279

Low

1217861

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

0

High-throughput

0.279

Low

1219456

SYNE2
Nesprin-2

1

0

High-throughput

0.279

Low

1219466

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.279

Low

1219471

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.279

Low

1219472

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.279

Low

1219478

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.279

Low

1219479

FBLN5
Fibulin-5

1

0

High-throughput

0.279

Low

133753

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

Small-scale

0.249

Low

414007

P53
Cellular tumor antigen p53

1

0

Small-scale

0.249

Low

486570

TACD2
Tumor-associated calcium signal transducer 2

1

0

Small-scale

0.249

Low

487415

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.249

Low

505639

ZH11B
Probable palmitoyltransferase ZDHHC11B

1

0

Small-scale

0.249

Low

562607

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.249

Low

582168

INGR1
Interferon gamma receptor 1

1

0

Small-scale

0.249

Low

595466

H15
Histone H1.5

1

0

Small-scale

0.249

Low

695682

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.249

Low

1089213

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.249

Low

1129292

BLTP2
Bridge-like lipid transfer protein family member 2

1

0

Small-scale

0.249

Low

1133458

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.249

Low

1150652

TRBP2
RISC-loading complex subunit TARBP2

1

0

Small-scale

0.249

Low

1219452

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

1219453

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

1219455

COP1
E3 ubiquitin-protein ligase COP1

1

0

High-throughput

0.249

Low

1219460

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

Small-scale

0.249

Low

1219463

MUS81
Structure-specific endonuclease subunit MUS81

1

0

Small-scale

0.249

Low

1219464

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

Small-scale

0.249

Low

1219465

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

0

Small-scale

0.249

Low

1219468

HEPH
Hephaestin

1

0

Small-scale

0.249

Low

1219470

TINF2
TERF1-interacting nuclear factor 2

1

0

Small-scale

0.249

Low

1219473

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.249

Low

1219476

POTE1
Protection of telomeres protein 1

1

0

Small-scale

0.249

Low

1219477

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

Small-scale

0.249

Low

261955

RNH1
Ribonuclease H1

1

0

High-throughput

0.232

Low

618145

K2C4
Keratin, type II cytoskeletal 4

1

0

High-throughput

0.232

Low

911269

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.232

Low

1219475

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.232

Low

1219480

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025