HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TTC3 (P53804)
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3)
Gene: TTC3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.747

Property	Details
Experiments	19285159
Identification Methods	pull down, affinity chromatography technology, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 2025
+	Hs
		475874 UBC_HUMAN (1-685): 0: 846: 100.00		TGO1_HUMAN (1104-1863): 1.22e-83: 308: 14.29
+	Hs
		213459 UBC_HUMAN (1-685): 0: 846: 100.00		SGTA_HUMAN (220-333): 1.13e-24: 108: 29.83
+	Hs
		174570 UBC_HUMAN (1-685): 0: 846: 100.00		OGT1_HUMAN (81-443): 8.81e-20: 98.9: 10.24
+	Hs
		475882 UBC_HUMAN (1-685): 0: 846: 100.00		FKB15_HUMAN (1149-1867): 1.07e-13: 79.3: 10.36
+	Sc
		477102 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		STI1_YEAST (204-465): 1.99e-15: 84.1: 16.42
+	Mm
		476971 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN111_MOUSE (1722-2006): 3.42e-54: 209: 14.04
+	Mm
		924235 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		PPP5_MOUSE (220-360): 1.31e-43: 169: 30.50
+	Rn
		1144228 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SGTB_RAT (223-348): 1.92e-41: 157: 24.60
+	Hs
		213522 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		SGTA_HUMAN (220-333): 1.13e-24: 108: 29.83
+	Rn
		193485 UBC_RAT (1-108): 1.27e-29: 127: 90.74		STIP1_RAT (24-510): 9.82e-24: 110: 12.10
+	Rn
		251113 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SGTA_RAT (220-348): 6.23e-24: 106: 27.91
+	Rn
		881491 UBC_RAT (1-108): 1.27e-29: 127: 90.74		OGT1_RAT (81-443): 5.58e-20: 99.7: 10.24
+	Rn
		1144220 UBC_RAT (1-108): 1.27e-29: 127: 90.74		TOM70_RAT (28-354): 2.82e-10: 67.3: 11.98
+	Rn
		655929 UBC_RAT (1-108): 1.27e-29: 127: 90.74		DCTN1_RAT (1540-1742): 2.17e-09: 65: 10.75