Protein: S100B
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)

Gene: S100B
Organism: Homo sapiens
Interactions: 199
UniProt ID: P04271

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380736

S10A1
Protein S100-A1

12

17

Small-scale

0.986

High

380713

S100B
Protein S100-B

10

17

Small-scale

0.983

High

380739

S10A4
Protein S100-A4

5

17

High-throughput

0.935

High

380742

S10A2
Protein S100-A2

4

17

High-throughput

0.911

High

380738

S100P
Protein S100-P

4

17

High-throughput

0.909

High

380718

S10A6
Protein S100-A6

3

17

Small-scale

0.880

High

380714

P53
Cellular tumor antigen p53

4

16

Small-scale

0.874

High

380779

RAGE
Advanced glycosylation end product-specific receptor

3

9

Small-scale

0.861

High

380751

IQGA1
Ras GTPase-activating-like protein IQGAP1

2

5

Small-scale

0.834

High

380717

S10A9
Protein S100-A9

2

17

High-throughput

0.783

High

380823

S100Z
Protein S100-Z

2

17

High-throughput

0.783

High

380745

S10AB
Protein S100-A11

1

17

Small-scale

0.740

High

380780

STK38
Serine/threonine-protein kinase 38

1

9

Small-scale

0.724

High

380766

CDK17
Cyclin-dependent kinase 17

1

12

High-throughput

0.691

High

380769

CDK18
Cyclin-dependent kinase 18

1

12

High-throughput

0.691

High

380776

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

5

High-throughput

0.691

High

380795

RFIP1
Rab11 family-interacting protein 1

1

3

High-throughput

0.691

High

380810

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

1

High-throughput

0.691

High

380820

IASPP
RelA-associated inhibitor

1

2

High-throughput

0.691

High

380846

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

1

High-throughput

0.691

High

380863

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

12

High-throughput

0.691

High

380872

ASB6
Ankyrin repeat and SOCS box protein 6

1

4

High-throughput

0.691

High

380892

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

2

High-throughput

0.691

High

380874

SPG21
Maspardin

4

0

High-throughput

0.668

High

380732

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

4

High-throughput

0.665

High

380790

Q5T7Y6
Protein S100

1

17

High-throughput

0.665

High

380719

ANXA6
Annexin A6

1

11

Small-scale

0.647

High

380782

KS6A1
Ribosomal protein S6 kinase alpha-1

1

10

Small-scale

0.647

High

380723

TAU
Microtubule-associated protein tau

3

12

Small-scale

0.646

High

380753

KC1D
Casein kinase I isoform delta

1

0

High-throughput

0.630

High

380882

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.630

High

380767

MDM2
E3 ubiquitin-protein ligase Mdm2

2

9

Small-scale

0.629

High

380759

CAZA1
F-actin-capping protein subunit alpha-1

2

4

Small-scale

0.619

High

380720

FGF2
Fibroblast growth factor 2

1

1

Small-scale

0.618

High

132711

SDCB1
Syntenin-1

2

2

High-throughput

0.606

High

380815

LNX1
E3 ubiquitin-protein ligase LNX

2

3

High-throughput

0.606

High

169226

MDM4
Protein Mdm4

2

9

Small-scale

0.602

High

380733

IL11
Interleukin-11

2

3

Small-scale

0.602

High

380889

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

0

High-throughput

0.602

High

380802

CPNE8
Copine-8

1

1

High-throughput

0.594

High

380774

AF1Q
Protein AF1q

2

0

High-throughput

0.585

High

380729

VAV
Proto-oncogene vav

1

8

Small-scale

0.561

High

380749

PGM1
Phosphoglucomutase-1

1

1

Small-scale

0.561

High

380772

AHNK
Neuroblast differentiation-associated protein AHNAK

1

3

Small-scale

0.561

High

380828

B2CL2
Bcl-2-like protein 2

1

1

High-throughput

0.560

High

380743

IMPA1
Inositol monophosphatase 1

1

1

Small-scale

0.536

High

50544

PKHG3
Pleckstrin homology domain-containing family G member 3

1

7

High-throughput

0.536

High

166155

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

8

High-throughput

0.536

High

167126

ZN536
Zinc finger protein 536

1

3

High-throughput

0.536

High

206787

FOXO3
Forkhead box protein O3

1

7

High-throughput

0.536

High

206999

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.536

High

264159

CDC45
Cell division control protein 45 homolog

1

1

High-throughput

0.536

High

272470

OFD1
Centriole and centriolar satellite protein OFD1

1

17

High-throughput

0.536

High

330539

ZBED1
E3 SUMO-protein ligase ZBED1

1

3

High-throughput

0.536

High

380727

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.536

High

380731

ZNF3
Zinc finger protein 3

1

4

High-throughput

0.536

High

380737

JAK1
Tyrosine-protein kinase JAK1

1

9

High-throughput

0.536

High

380744

PML
Protein PML

1

6

High-throughput

0.536

High

380752

NRIP1
Nuclear receptor-interacting protein 1

1

2

High-throughput

0.536

High

380754

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.536

High

380757

ERF
ETS domain-containing transcription factor ERF

1

7

High-throughput

0.536

High

380758

ZN136
Zinc finger protein 136

1

3

High-throughput

0.536

High

380760

ALR
FAD-linked sulfhydryl oxidase ALR

1

3

High-throughput

0.536

High

380765

FOXO4
Forkhead box protein O4

1

6

High-throughput

0.536

High

380773

MYO1E
Unconventional myosin-Ie

1

12

High-throughput

0.536

High

380778

MAP7
Ensconsin

1

5

High-throughput

0.536

High

380781

MTFR1
Mitochondrial fission regulator 1

1

4

High-throughput

0.536

High

380783

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.536

High

380786

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

1

High-throughput

0.536

High

380789

RHG21
Rho GTPase-activating protein 21

1

9

High-throughput

0.536

High

380791

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.536

High

380792

SYDE2
Rho GTPase-activating protein SYDE2

1

9

High-throughput

0.536

High

380793

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.536

High

380797

KDM3B
Lysine-specific demethylase 3B

1

1

High-throughput

0.536

High

380799

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

2

High-throughput

0.536

High

380800

LIPB1
Liprin-beta-1

1

15

High-throughput

0.536

High

380801

ZC3C1
Zinc finger C3HC-type protein 1

1

2

High-throughput

0.536

High

380803

ARI3B
AT-rich interactive domain-containing protein 3B

1

4

High-throughput

0.536

High

380804

MA7D3
MAP7 domain-containing protein 3

1

2

High-throughput

0.536

High

380806

TIGD4
Tigger transposable element-derived protein 4

1

2

High-throughput

0.536

High

380809

CNTRB
Centrobin

1

13

High-throughput

0.536

High

380812

CE112
Centrosomal protein of 112 kDa

1

14

High-throughput

0.536

High

380813

ZN709
Zinc finger protein 709

1

1

High-throughput

0.536

High

380814

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.536

High

380817

ZN507
Zinc finger protein 507

1

4

High-throughput

0.536

High

380827

ZN516
Zinc finger protein 516

1

4

High-throughput

0.536

High

380832

TTC28
Tetratricopeptide repeat protein 28

1

3

High-throughput

0.536

High

380835

ZBT10
Zinc finger and BTB domain-containing protein 10

1

7

High-throughput

0.536

High

380838

ZN764
Zinc finger protein 764

1

5

High-throughput

0.536

High

380839

SENP5
Sentrin-specific protease 5

1

4

High-throughput

0.536

High

380842

HIC2
Hypermethylated in cancer 2 protein

1

4

High-throughput

0.536

High

380844

ZN714
Zinc finger protein 714

1

2

High-throughput

0.536

High

380847

PUS7
Pseudouridylate synthase 7 homolog

1

2

High-throughput

0.536

High

380849

ATAD5
ATPase family AAA domain-containing protein 5

1

1

High-throughput

0.536

High

380850

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

1

High-throughput

0.536

High

380851

PIMRE
Protein PIMREG

1

1

High-throughput

0.536

High

380852

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

1

1

High-throughput

0.536

High

380855

CC106
Coiled-coil domain-containing protein 106

1

1

High-throughput

0.536

High

380856

SALL3
Sal-like protein 3

1

9

High-throughput

0.536

High

380858

TB182
182 kDa tankyrase-1-binding protein

1

2

High-throughput

0.536

High

380859

MTMRC
Myotubularin-related protein 12

1

6

High-throughput

0.536

High

380860

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.536

High

380861

TXNIP
Thioredoxin-interacting protein

1

5

High-throughput

0.536

High

380866

SENP2
Sentrin-specific protease 2

1

4

High-throughput

0.536

High

380867

RESF1
Retroelement silencing factor 1

1

1

High-throughput

0.536

High

380868

SALL1
Sal-like protein 1

1

6

High-throughput

0.536

High

380871

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.536

High

380875

ZBTB4
Zinc finger and BTB domain-containing protein 4

1

2

High-throughput

0.536

High

380878

INT6
Integrator complex subunit 6

1

6

High-throughput

0.536

High

380879

ZBT21
Zinc finger and BTB domain-containing protein 21

1

3

High-throughput

0.536

High

380880

TTF2
Transcription termination factor 2

1

13

High-throughput

0.536

High

380881

PHF8
Histone lysine demethylase PHF8

1

1

High-throughput

0.536

High

380883

SCML2
Sex comb on midleg-like protein 2

1

4

High-throughput

0.536

High

380884

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

1

High-throughput

0.536

High

380886

SALL2
Sal-like protein 2

1

6

High-throughput

0.536

High

380887

ZN451
E3 SUMO-protein ligase ZNF451

1

3

High-throughput

0.536

High

361423

APOE
Apolipoprotein E

1

0

High-throughput

0.518

High

148027

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

2

High-throughput

0.515

High

269116

DAB1
Disabled homolog 1

1

1

High-throughput

0.515

High

380716

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.515

High

380722

HS71A
Heat shock 70 kDa protein 1A

1

6

High-throughput

0.515

High

380730

ZNF24
Zinc finger protein 24

1

3

High-throughput

0.515

High

380734

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

15

High-throughput

0.515

High

380740

CALX
Calnexin

1

1

High-throughput

0.515

High

380761

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.515

High

380763

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.515

High

380768

APLP2
Amyloid beta precursor like protein 2

1

3

High-throughput

0.515

High

380770

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.515

High

380777

BLMH
Bleomycin hydrolase

1

2

High-throughput

0.515

High

380888

TRAF6
TNF receptor-associated factor 6

1

13

High-throughput

0.515

High

316466

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.513

High

380741

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.513

High

380747

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

380755

PRI1
DNA primase small subunit

1

0

High-throughput

0.513

High

380756

PRI2
DNA primase large subunit

1

0

High-throughput

0.513

High

380762

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

380764

NOP14
Nucleolar protein 14

1

0

High-throughput

0.513

High

380771

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.513

High

380775

ORC2
Origin recognition complex subunit 2

1

0

High-throughput

0.513

High

380787

SGO2
Shugoshin 2

1

0

High-throughput

0.513

High

380805

SLF2
SMC5-SMC6 complex localization factor protein 2

1

0

High-throughput

0.513

High

380807

RAVR1
Ribonucleoprotein PTB-binding 1

1

0

High-throughput

0.513

High

380819

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.513

High

380824

ELYS
Protein ELYS

1

0

High-throughput

0.513

High

380840

REXO5
RNA exonuclease 5

1

0

High-throughput

0.513

High

380848

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

380853

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.513

High

380854

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.513

High

380857

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.513

High

380862

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.513

High

380865

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.513

High

380870

DCA13
DDB1- and CUL4-associated factor 13

1

0

High-throughput

0.513

High

380873

CARF
CDKN2A-interacting protein

1

0

High-throughput

0.513

High

380890

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.513

High

352856

IFNB
Interferon beta

1

6

Small-scale

0.501

High

380746

NAC1
Sodium/calcium exchanger 1

1

17

Small-scale

0.501

High

380748

MYH9
Myosin-9

1

12

Small-scale

0.501

High

380818

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

12

Small-scale

0.501

High

380845

CEP20
Centrosomal protein 20

1

5

Small-scale

0.501

High

380885

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

344401

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.493

High

380726

UNG
Uracil-DNA glycosylase

1

0

High-throughput

0.493

High

380750

NBL1
Neuroblastoma suppressor of tumorigenicity 1

1

0

High-throughput

0.493

High

380784

NEDD8
NEDD8

1

0

High-throughput

0.493

High

380735

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

1

1

High-throughput

0.489

High

380785

CR021
UPF0711 protein C18orf21

1

5

High-throughput

0.489

High

380788

NHSL1
NHS-like protein 1

1

5

High-throughput

0.489

High

380798

UBE3B
Ubiquitin-protein ligase E3B

1

4

High-throughput

0.489

High

380808

RCOR2
REST corepressor 2

1

1

High-throughput

0.489

High

380831

C102A
Coiled-coil domain-containing protein 102A

1

14

High-throughput

0.489

High

380834

FWCH2
FLYWCH family member 2

1

1

High-throughput

0.489

High

380891

HEMK1
MTRF1L release factor glutamine methyltransferase

1

2

High-throughput

0.489

High

380830

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.486

High

380794

ATRAP
Type-1 angiotensin II receptor-associated protein

1

1

High-throughput

0.481

High

380829

MAL2
Protein MAL2

1

1

High-throughput

0.481

High

181756

SOCS1
Suppressor of cytokine signaling 1

1

4

Small-scale

0.479

High

324158

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

380724

FGFR1
Fibroblast growth factor receptor 1

1

4

Small-scale

0.479

High

380725

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

Small-scale

0.479

High

380821

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

380837

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.460

High

380825

NDRG1
Protein NDRG1

1

0

Small-scale

0.458

High

380822

TM239
Transmembrane protein 239

1

1

High-throughput

0.439

High

380833

LDAF1
Lipid droplet assembly factor 1

1

1

High-throughput

0.439

High

380843

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

2

High-throughput

0.439

High

380877

PRAF1
Prenylated Rab acceptor protein 1

1

1

High-throughput

0.439

High

380715

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

380721

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.279

Low

380728

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.279

Low

380811

MET25
Probable methyltransferase-like protein 25

1

0

High-throughput

0.279

Low

380816

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.279

Low

380836

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

380864

CPLN1
Ciliogenesis and planar polarity effector 1

1

0

High-throughput

0.279

Low

380869

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.279

Low

380826

SEPT8
Septin-8

1

0

High-throughput

0.268

Low

380876

CRCT1
Cysteine-rich C-terminal protein 1

1

0

High-throughput

0.268

Low

380796

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.265

Low

380841

ADTRP
Androgen-dependent TFPI-regulating protein

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024