Protein: VGLL3
Transcription cofactor vestigial-like protein 3 (Vgl-3)

Gene: VGLL3
Organism: Homo sapiens
Interactions: 71
UniProt ID: A8MV65

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

71108

TEAD4
Transcriptional enhancer factor TEF-3

3

12

High-throughput

0.836

High

71094

TEAD1
Transcriptional enhancer factor TEF-1

2

12

High-throughput

0.783

High

71109

TEAD2
Transcriptional enhancer factor TEF-4

2

12

High-throughput

0.783

High

71141

TEAD3
Transcriptional enhancer factor TEF-5

2

12

High-throughput

0.783

High

71103

PITX1
Pituitary homeobox 1

2

1

High-throughput

0.606

High

71142

PITX2
Pituitary homeobox 2

2

1

High-throughput

0.606

High

71105

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

71124

POGZ
Pogo transposable element with ZNF domain

2

0

High-throughput

0.580

High

71135

SMRC1
SWI/SNF complex subunit SMARCC1

2

0

High-throughput

0.580

High

71136

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.580

High

71138

SMIP9
Protein SPMIP9

2

0

High-throughput

0.580

High

71139

LENG8
Leukocyte receptor cluster member 8

2

0

High-throughput

0.580

High

71140

TBX15
T-box transcription factor TBX15

2

0

High-throughput

0.580

High

71143

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

71145

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

71095

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

71096

KR122
Keratin-associated protein 12-2

2

12

High-throughput

0.553

High

71097

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

71098

KR107
Keratin-associated protein 10-7

2

9

High-throughput

0.553

High

71099

KR108
Keratin-associated protein 10-8

2

10

High-throughput

0.553

High

71100

KR109
Keratin-associated protein 10-9

2

11

High-throughput

0.553

High

71104

KRA11
Keratin-associated protein 1-1

2

10

High-throughput

0.553

High

71115

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.553

High

71117

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.553

High

71120

KR511
Keratin-associated protein 5-11

2

10

High-throughput

0.553

High

71129

TRI42
Tripartite motif-containing protein 42

2

1

High-throughput

0.553

High

71147

KRA98
Keratin-associated protein 9-8

2

11

High-throughput

0.553

High

71148

KRA93
Keratin-associated protein 9-3

2

11

High-throughput

0.553

High

71149

KRA92
Keratin-associated protein 9-2

2

11

High-throughput

0.553

High

71150

KR411
Keratin-associated protein 4-11

2

12

High-throughput

0.553

High

71151

KRA42
Keratin-associated protein 4-2

2

12

High-throughput

0.553

High

71152

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.553

High

71153

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

71093

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

71155

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

71133

TSC1
Hamartin

1

2

High-throughput

0.481

High

71102

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

71126

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

71130

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.460

High

71157

KDM5B
Lysine-specific demethylase 5B

1

0

Small-scale

0.458

High

71125

DTX2
Probable E3 ubiquitin-protein ligase DTX2

3

0

High-throughput

0.340

High

50305

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.316

High

70028

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

71089

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

71090

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.316

High

71091

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

71092

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

71106

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.316

High

71110

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

71111

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

71112

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

71113

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

71114

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

71116

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

71118

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.316

High

71119

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

71121

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

71122

UFSP1
Ufm1-specific protease 1

2

0

High-throughput

0.316

High

71123

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

71127

KR191
Keratin-associated protein 19-1

2

0

High-throughput

0.316

High

71128

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

71132

OXER1
Oxoeicosanoid receptor 1

2

0

High-throughput

0.316

High

71134

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.316

High

71144

CTRC
Chymotrypsin-C

2

0

High-throughput

0.316

High

71146

CNFN
Cornifelin

2

0

High-throughput

0.316

High

71154

SMOC1
SPARC-related modular calcium-binding protein 1

2

0

High-throughput

0.316

High

71156

ESM1
Endothelial cell-specific molecule 1

2

0

High-throughput

0.316

High

71137

MY15B
Unconventional myosin-XVB

1

0

High-throughput

0.268

Low

71101

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

71131

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low

71107

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025