Protein: URB2
Unhealthy ribosome biogenesis protein 2 homolog

Gene: URB2
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q14146

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0016235 - aggresome
GO:0030496 - midbody
GO:0042254 - ribosome biogenesis
GO:1901796 - regulation of signal transduction by p53 class mediator

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

208256

RRP8
Ribosomal RNA-processing protein 8

3

0

High-throughput

0.634

High

1006391

SRPK2
SRSF protein kinase 2

2

1

High-throughput

0.628

High

1121606

SCN3B
Sodium channel regulatory subunit beta-3

3

1

High-throughput

0.604

High

841360

RBM34
RNA-binding protein 34

2

0

High-throughput

0.602

High

1121580

NOL8
Nucleolar protein 8

2

0

High-throughput

0.602

High

1121596

RBM4
RNA-binding protein 4

2

0

High-throughput

0.602

High

140912

NOP56
Nucleolar protein 56

2

0

High-throughput

0.585

High

824139

RL13A
Large ribosomal subunit protein uL13

2

0

High-throughput

0.576

High

770854

OPRM
Mu-type opioid receptor

2

2

High-throughput

0.574

High

371998

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1101257

SLAF1
Signaling lymphocytic activation molecule

2

1

High-throughput

0.558

High

833108

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

1089649

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.536

High

396089

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

428760

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

686153

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

785159

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

855073

NOP2
28S rRNA

1

0

High-throughput

0.513

High

978521

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

1121598

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

1121602

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

1121612

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1121614

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

165940

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

182530

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.489

High

286980

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

3

High-throughput

0.489

High

771120

APJ
Apelin receptor

1

2

High-throughput

0.489

High

1121587

SPSB4
SPRY domain-containing SOCS box protein 4

1

1

High-throughput

0.489

High

1121593

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.489

High

385732

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

Small-scale

0.481

High

1121577

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

190902

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

223026

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

347699

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

447007

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

487297

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

810092

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

955155

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.458

High

978925

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

982659

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1121597

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1121601

ANLN
Anillin

1

0

High-throughput

0.458

High

1121603

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1121609

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1121613

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

634435

LMNB1
Lamin-B1

1

1

Small-scale

0.457

High

345800

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.437

High

404050

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

1121586

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1121575

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

638414

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.407

High

669320

ACKR3
Atypical chemokine receptor 3

1

3

High-throughput

0.407

High

546971

FGF3
Fibroblast growth factor 3

2

0

High-throughput

0.328

High

904699

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.328

High

1037489

RL18A
Large ribosomal subunit protein eL20

2

0

High-throughput

0.328

High

1121583

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1121590

ZN512
Zinc finger protein 512

2

0

High-throughput

0.328

High

1121607

TAP26
Thyroid transcription factor 1-associated protein 26

2

0

High-throughput

0.328

High

1121608

H2AW
Core histone macro-H2A.2

2

0

High-throughput

0.328

High

50552

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.313

High

859824

RL28
Large ribosomal subunit protein eL28

2

0

High-throughput

0.313

High

1022386

IDD
Integral membrane protein DGCR2/IDD

2

0

High-throughput

0.313

High

191640

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

292627

RENR
Renin receptor

1

0

High-throughput

0.279

Low

388193

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

596097

H12
Histone H1.2

1

0

High-throughput

0.279

Low

624057

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

0

High-throughput

0.279

Low

657233

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

960719

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

997709

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.279

Low

1121574

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1121581

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

1121584

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1121585

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

1121591

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.279

Low

1121592

OPALI
Opalin

1

0

High-throughput

0.279

Low

1121594

SORT
Sortilin

1

0

High-throughput

0.279

Low

1121604

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.279

Low

647437

SCP2
Sterol carrier protein 2

1

0

High-throughput

0.269

Low

1121576

PLEC
Plectin

1

0

High-throughput

0.269

Low

1121589

WDR89
WD repeat-containing protein 89

1

0

High-throughput

0.269

Low

272159

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

588668

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695429

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768162

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

898646

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.249

Low

937748

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.249

Low

984757

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

1004552

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1099875

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1105915

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.249

Low

1106848

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1121578

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1121579

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1121582

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.249

Low

1121588

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.249

Low

1121599

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1121610

RRBP1
Ribosome-binding protein 1

1

0

High-throughput

0.249

Low

1121611

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

601665

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.232

Low

683239

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

704008

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

1121595

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.232

Low

1121600

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.232

Low

1121605

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025