Protein: SPC25
Kinetochore protein Spc25 (Chromosome alignment defect 2) (Mitotic chaos)

Gene: SPC25
Organism: Drosophila melanogaster
Interactions: 108
UniProt ID: Q9V3V7

Gene Ontology (top 5):
GO:0000212 - meiotic spindle organization
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0007080 - mitotic metaphase chromosome alignment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1464549

Q9VYB1
Kinetochore protein NDC80

4

0

Small-scale

0.654

High

1263596

Q7JZC9
Nnf1a

2

1

Small-scale

0.584

High

1304988

Q8IPW3
Nnf1b

2

1

Small-scale

0.584

High

1464524

Q9VM45
Nuf2

2

0

Small-scale

0.559

High

1464534

Q9VS01
Mis12

2

0

Small-scale

0.559

High

1464550

Q9VYX4
CG1558-RA protein

2

0

Small-scale

0.559

High

1464562

Q9XZ57
Eb1, isoform E

2

0

Small-scale

0.547

High

119533

M9NHC5
Uncharacterized protein, isoform C

1

1

High-throughput

0.479

High

1234377

Q6IKI1
HDC12388

1

0

Small-scale

0.458

High

1464516

Q9VHP9
Centromeric protein-C, isoform A

1

0

Small-scale

0.458

High

1464517

CL190
Restin homolog

1

0

Small-scale

0.458

High

1176562

NLP
Nucleoplasmin-like protein

1

1

High-throughput

0.445

High

1464507

Q9VAC4
GEO09167p1

1

1

High-throughput

0.445

High

1464545

Q9VWG1
LD37169p

1

1

High-throughput

0.445

High

195078

O16043
Anon1A4

1

0

High-throughput

0.426

High

356391

O97102
Small ubiquitin-related modifier

1

0

High-throughput

0.426

High

556723

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.426

High

929004

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

1019889

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.426

High

1260836

Q76NR6
Regucalcin

1

0

High-throughput

0.426

High

1267918

TERA
Transitional endoplasmic reticulum ATPase TER94

1

0

High-throughput

0.426

High

1268256

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.426

High

1303919

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

1321679

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

1343014

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.426

High

1345246

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

1440030

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

1463650

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

1464504

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.426

High

1464505

THIO2
Thioredoxin-2

1

0

High-throughput

0.426

High

1464506

Q9V9U3
LD45254p

1

0

High-throughput

0.426

High

1464514

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

1464531

BACC
Bacchus

1

0

High-throughput

0.426

High

1464533

Q9VRL1
GEO06356p1

1

0

High-throughput

0.426

High

1464539

Q9VUC1
Hsc70Cb, isoform A

1

0

High-throughput

0.426

High

1464553

Q9W0H8
Reticulocalbin-3

1

0

High-throughput

0.426

High

1464554

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

1464556

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.426

High

1464558

WUHO
tRNA

1

0

High-throughput

0.426

High

1464559

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

1464563

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.426

High

54043

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

57599

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.407

High

121270

ALDR
Aldo-keto reductase 1B

1

2

High-throughput

0.407

High

871651

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

2

High-throughput

0.407

High

929525

PDI
Protein disulfide-isomerase

1

1

High-throughput

0.407

High

1191676

Q3YMU0
Protein disulfide-isomerase

1

1

High-throughput

0.407

High

1262143

Q7JVH6
LD24696p

1

2

High-throughput

0.407

High

1262833

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

1464513

Q9VGK3
peptidylprolyl isomerase

1

2

High-throughput

0.407

High

1464522

FKB59
FK506-binding protein 59

1

2

High-throughput

0.407

High

1464535

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.407

High

1464536

Q9VTY2
Uncharacterized protein, isoform A

1

2

High-throughput

0.407

High

1464548

CLIC
Chloride intracellular channel Clic

1

1

High-throughput

0.407

High

1464552

Q9W022
GEO01508p1

1

1

High-throughput

0.407

High

1464561

Q9XYZ9
Glutathione S transferase E12, isoform A

1

1

High-throughput

0.407

High

1464538

Q9VU35
10 kDa heat shock protein, mitochondrial

2

0

High-throughput

0.298

High

1464525

Q9VML8
GH01721p

1

0

High-throughput

0.282

High

1464527

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.265

Low

1464542

DTBP1
Dysbindin protein homolog

1

0

High-throughput

0.265

Low

122327

M9PIC9
Spc105-related, isoform B

1

0

Small-scale

0.249

Low

1464537

Q9VU15
Splicing factor 3A subunit 2

1

0

Small-scale

0.249

Low

1464540

Q9VUM1
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

Small-scale

0.249

Low

57825

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

86532

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.232

Low

197818

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.232

Low

304664

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.232

Low

357327

O97428
Ciboulot, isoform A

1

0

High-throughput

0.232

Low

357550

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.232

Low

476985

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low

930175

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

1019626

TRXR1
Thioredoxin reductase 1, mitochondrial

1

0

High-throughput

0.232

Low

1031222

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

1265263

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

1269460

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.232

Low

1305727

Q8IQZ7
FI19014p1

1

0

High-throughput

0.232

Low

1306106

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.232

Low

1374522

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

1377642

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

1427842

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.232

Low

1445384

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.232

Low

1445623

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.232

Low

1464508

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.232

Low

1464509

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1464510

Q9VD02
GH14779p

1

0

High-throughput

0.232

Low

1464511

Q9VEB1
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1464512

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

1464515

Q9VHN7
transketolase

1

0

High-throughput

0.232

Low

1464518

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.232

Low

1464519

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

1464520

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

0

High-throughput

0.232

Low

1464521

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

1464523

AK200
A-kinase anchor protein 200

1

0

High-throughput

0.232

Low

1464526

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

1464528

Q9VP52
GH24315p

1

0

High-throughput

0.232

Low

1464529

Q9VPN5
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.232

Low

1464530

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.232

Low

1464532

Q9VRD6
NTF2-related export protein

1

0

High-throughput

0.232

Low

1464541

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

1464543

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.232

Low

1464544

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

1464546

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

1464547

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.232

Low

1464551

Q9VZI1
Transgelin

1

0

High-throughput

0.232

Low

1464555

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

1464557

CISY
Probable citrate synthase, mitochondrial

1

0

High-throughput

0.232

Low

1464560

Q9W478
RE43153p

1

0

High-throughput

0.232

Low

1464564

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025