Protein: COPB
Coatomer subunit beta (Beta-coat protein) (Beta-COP)

Gene: COPB, betaCOP
Organism: Drosophila melanogaster
Interactions: 121
UniProt ID: P45437

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0005794 - Golgi apparatus
GO:0006886 - intracellular protein transport
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

829626

ARF4
ADP ribosylation factor 4

1

20

Small-scale

0.618

High

852168

ARF1
ADP-ribosylation factor 1

1

20

Small-scale

0.618

High

852192

COPG
Coatomer subunit gamma

1

16

High-throughput

0.575

High

715078

CLH
Clathrin heavy chain

2

7

High-throughput

0.571

High

55414

A1Z9E3
Elongation factor Tu

2

1

High-throughput

0.521

High

704333

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

1

High-throughput

0.521

High

852165

TCPG
T-complex protein 1 subunit gamma

2

1

High-throughput

0.521

High

852193

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

2

2

High-throughput

0.521

High

852200

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

1

High-throughput

0.521

High

852207

Q9V455
Importin subunit alpha

2

1

High-throughput

0.521

High

852208

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

1

High-throughput

0.521

High

852222

IPO9
Importin-9

2

12

High-throughput

0.521

High

852242

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

4

High-throughput

0.521

High

852249

Q9VZL3
very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.521

High

852171

ARL2
ADP-ribosylation factor-like protein 2

1

20

High-throughput

0.514

High

852191

STX4
Syntaxin-4

1

0

High-throughput

0.486

High

852234

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

3

High-throughput

0.479

High

852170

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

2

High-throughput

0.464

High

852172

ROP
Protein ROP

1

5

High-throughput

0.445

High

852252

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

High-throughput

0.445

High

56197

A1ZA03
Pms2

1

4

High-throughput

0.439

High

52645

A1Z729
NADP-retinol dehydrogenase

1

2

High-throughput

0.437

High

541187

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

6

High-throughput

0.437

High

852169

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

1

High-throughput

0.437

High

852177

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

5

High-throughput

0.437

High

852183

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

852188

Q7KN97
Pyruvate carboxylase

1

3

High-throughput

0.437

High

852190

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.437

High

852212

Q9VAL7
Calnexin 99A, isoform A

1

2

High-throughput

0.437

High

852236

Q9VQL1
serine--tRNA ligase

1

1

High-throughput

0.437

High

852175

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.426

High

852176

CANA
Calpain-A

1

0

High-throughput

0.426

High

852189

DYM
Dymeclin

1

0

High-throughput

0.426

High

852233

Q9VPX5
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.426

High

303853

O76417
MutL homolog PMS2

1

4

High-throughput

0.417

High

55763

A1Z9K0
Uncharacterized protein, isoform B

1

1

High-throughput

0.407

High

58075

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

263363

PENG
Protein penguin

1

1

High-throughput

0.407

High

304188

ERD2
ER lumen protein-retaining receptor

1

1

High-throughput

0.407

High

355919

O96692
small monomeric GTPase

1

3

High-throughput

0.407

High

473594

RAS1
Ras-like protein 1

1

2

High-throughput

0.407

High

852164

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.407

High

852167

POLO
Serine/threonine-protein kinase polo

1

5

High-throughput

0.407

High

852173

Q0E931
GTP-binding protein 1

1

3

High-throughput

0.407

High

852174

Q0E9E2
Pyruvate carboxylase

1

3

High-throughput

0.407

High

852178

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

5

High-throughput

0.407

High

852180

MCM4
DNA replication licensing factor MCM4

1

2

High-throughput

0.407

High

852181

SARM1
NAD(+) hydrolase sarm1

1

3

High-throughput

0.407

High

852182

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

852184

Q7JXU4
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.407

High

852186

Q7KMQ0
26S proteasome regulatory subunit 7

1

5

High-throughput

0.407

High

852195

Q8SY39
ATP-dependent RNA helicase DDX54

1

2

High-throughput

0.407

High

852197

ENA
Protein enabled

1

3

High-throughput

0.407

High

852198

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

4

High-throughput

0.407

High

852199

Q8T8W3
AT21416p

1

14

High-throughput

0.407

High

852202

Q960C7
NADP-retinol dehydrogenase

1

2

High-throughput

0.407

High

852203

Q9V3V6
26S proteasome regulatory complex subunit p50

1

9

High-throughput

0.407

High

852204

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.407

High

852210

Q9V9S0
FI04419p

1

6

High-throughput

0.407

High

852211

Q9VAH7
N-terminal kinase-like protein

1

6

High-throughput

0.407

High

852216

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

2

High-throughput

0.407

High

852218

Q9VEH0
Aluminum tubes, isoform A

1

12

High-throughput

0.407

High

852219

FLNA
Filamin-A

1

3

High-throughput

0.407

High

852221

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

7

High-throughput

0.407

High

852224

Q9VI53
LD44267p

1

10

High-throughput

0.407

High

852225

DDX47
ATP-dependent RNA helicase DDX47

1

1

High-throughput

0.407

High

852226

RAGP1
Ran GTPase-activating protein

1

3

High-throughput

0.407

High

852229

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.407

High

852231

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.407

High

852240

FRL
Formin-like protein

1

5

High-throughput

0.407

High

852245

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

1

High-throughput

0.407

High

852247

RENT1
Regulator of nonsense transcripts 1 homolog

1

1

High-throughput

0.407

High

852248

Q9VZ88
AT07585p

1

3

High-throughput

0.407

High

852251

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.407

High

852254

Q9W3N1
RH59310p

1

3

High-throughput

0.407

High

852255

Q9W414
Regulatory particle triple-A ATPase 4

1

5

High-throughput

0.407

High

852256

MCM7
DNA replication licensing factor Mcm7

1

2

High-throughput

0.407

High

852258

SYQ
Probable glutamine--tRNA ligase

1

1

High-throughput

0.407

High

437977

PYR1
Multifunctional protein r

2

0

High-throughput

0.298

High

782693

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

0

High-throughput

0.298

High

852213

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

0

High-throughput

0.298

High

852230

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.298

High

852243

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

0

High-throughput

0.298

High

838822

GRK
Protein gurken

1

0

High-throughput

0.282

High

852227

Q9VJC1
GH17679p

1

0

High-throughput

0.265

Low

68904

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

852185

Q7K3J0
T-complex protein 1 subunit theta

1

0

High-throughput

0.249

Low

852187

Q7KN94
Electron transfer flavoprotein subunit alpha

1

0

High-throughput

0.249

Low

852237

Q9VQL7
Fatty acid synthase

1

0

High-throughput

0.249

Low

53111

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

360522

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

460002

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

564956

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

0

High-throughput

0.232

Low

669683

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.232

Low

823744

SQH
Myosin regulatory light chain sqh

1

0

High-throughput

0.232

Low

834832

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

852163

ACTZ
Actin-related protein 1

1

0

High-throughput

0.232

Low

852166

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.232

Low

852179

NETB
Netrin-B

1

0

High-throughput

0.232

Low

852194

Q8STG9
DSec61alpha

1

0

High-throughput

0.232

Low

852196

Q8SY53
GH11935p

1

0

High-throughput

0.232

Low

852201

Q95WY3
Nucleolar protein 56

1

0

High-throughput

0.232

Low

852205

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

852206

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

852209

Q9V9Q4
LD43819p

1

0

High-throughput

0.232

Low

852214

Q9VCF8
LD23561p

1

0

High-throughput

0.232

Low

852215

Q9VD22
LP02352p

1

0

High-throughput

0.232

Low

852217

Q9VDK7
Signal recognition particle subunit SRP72

1

0

High-throughput

0.232

Low

852220

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.232

Low

852223

Q9VH81
protein-serine/threonine phosphatase

1

0

High-throughput

0.232

Low

852228

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

852232

Q9VLX0
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

0

High-throughput

0.232

Low

852235

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

852238

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

852239

PATH
Proton-coupled amino acid transporter-like protein pathetic

1

0

High-throughput

0.232

Low

852241

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.232

Low

852244

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

852246

Q9VXR5
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.232

Low

852250

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

852253

Q9W1H8
acetyl-CoA C-acyltransferase

1

0

High-throughput

0.232

Low

852257

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025