Protein: Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A (EC 3.4.24.-) (SD01613p)

Gene: Q8T4G5, Afg3l2
Organism: Drosophila melanogaster
Interactions: 69
UniProt ID: Q8T4G5

Gene Ontology (top 5):
GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005745 - m-AAA complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1346045

LDH
L-lactate dehydrogenase

1

6

High-throughput

0.575

High

1346048

Q9V3V6
26S proteasome regulatory complex subunit p50

1

17

High-throughput

0.575

High

1346049

Q9V405
26S proteasome regulatory subunit 6B

1

9

High-throughput

0.575

High

1346076

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.575

High

1346085

Q9W414
Regulatory particle triple-A ATPase 4

1

6

High-throughput

0.575

High

756912

FAS2
Fasciclin-2

2

6

High-throughput

0.520

High

451808

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

1

High-throughput

0.514

High

55446

A1Z9E3
Elongation factor Tu

1

3

High-throughput

0.445

High

58092

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

6

High-throughput

0.445

High

704369

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

3

High-throughput

0.445

High

852945

ACTZ
Actin-related protein 1

1

5

High-throughput

0.445

High

875236

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.445

High

1173919

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

2

High-throughput

0.445

High

1175998

MCM4
DNA replication licensing factor MCM4

1

1

High-throughput

0.445

High

1234099

SARM1
NAD(+) hydrolase sarm1

1

2

High-throughput

0.445

High

1321433

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1344102

Q8SY39
ATP-dependent RNA helicase DDX54

1

3

High-throughput

0.445

High

1346046

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

2

High-throughput

0.445

High

1346051

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1346054

Q9VAH7
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1346056

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

3

High-throughput

0.445

High

1346064

DDX47
ATP-dependent RNA helicase DDX47

1

2

High-throughput

0.445

High

1346077

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.445

High

1346078

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1346080

RENT1
Regulator of nonsense transcripts 1 homolog

1

1

High-throughput

0.445

High

1346083

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.445

High

1346087

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.445

High

1264869

Q7K1L4
SD10469p

1

4

High-throughput

0.437

High

1346059

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.426

High

1346066

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

0

High-throughput

0.426

High

1346067

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.426

High

1346079

Q9VXR5
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.426

High

1346070

Q9VPR6
Kinase

1

2

High-throughput

0.417

High

53139

A1Z7K8
AaRS-interacting multifunctional protein 1

1

1

High-throughput

0.407

High

55788

A1Z9K0
Uncharacterized protein, isoform B

1

1

High-throughput

0.407

High

360553

COX2
Cytochrome c oxidase subunit 2

1

2

High-throughput

0.407

High

782740

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

3

High-throughput

0.407

High

852198

COPB
Coatomer subunit beta

1

4

High-throughput

0.407

High

1069744

Q0E931
GTP-binding protein 1

1

5

High-throughput

0.407

High

1070716

PCAT
Lysophosphatidylcholine acyltransferase

1

2

High-throughput

0.407

High

1263210

Q7JXU4
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.407

High

1343118

Q8STG9
DSec61alpha

1

2

High-throughput

0.407

High

1344222

Q8SY53
GH11935p

1

1

High-throughput

0.407

High

1346047

Q95WY3
Nucleolar protein 56

1

1

High-throughput

0.407

High

1346055

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

1

High-throughput

0.407

High

1346058

Q9VEH0
Aluminum tubes, isoform A

1

10

High-throughput

0.407

High

1346060

IPO9
Importin-9

1

4

High-throughput

0.407

High

1346061

Q9VGU4
FI02822p

1

9

High-throughput

0.407

High

1346062

ARL8
ADP-ribosylation factor-like protein 8

1

8

High-throughput

0.407

High

1346063

Q9VI53
LD44267p

1

9

High-throughput

0.407

High

1346068

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.407

High

1346069

GMDS
GDP-mannose 4,6 dehydratase

1

1

High-throughput

0.407

High

1346073

FRL
Formin-like protein

1

3

High-throughput

0.407

High

1346074

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.407

High

1346081

Q9VZ88
AT07585p

1

3

High-throughput

0.407

High

1346086

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

1

High-throughput

0.407

High

263386

PENG
Protein penguin

1

0

High-throughput

0.232

Low

1237005

Q6NP72
GEO09659p1

1

0

High-throughput

0.232

Low

1268338

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1346050

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

1346052

Q9V455
Importin subunit alpha

1

0

High-throughput

0.232

Low

1346053

Q9V9Q4
LD43819p

1

0

High-throughput

0.232

Low

1346057

Q9VDK7
Signal recognition particle subunit SRP72

1

0

High-throughput

0.232

Low

1346065

Q9VK46
Protein YIPF

1

0

High-throughput

0.232

Low

1346071

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1346072

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

1346075

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

0

High-throughput

0.232

Low

1346082

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

1346084

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025