Protein: PDGFB
Platelet-derived growth factor subunit B (PDGF subunit B) (PDGF-2) (Platelet-derived growth factor B chain) (Platelet-derived growth factor beta polypeptide) (Proto-oncogene c-Sis) (Becaplermin)

Gene: PDGFB
Organism: Homo sapiens
Interactions: 89
UniProt ID: P01127

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001525 - angiogenesis
GO:0001892 - embryonic placenta development
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002548 - monocyte chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376371

PGFRB
Platelet-derived growth factor receptor beta

7

20

Small-scale

0.969

High

376362

PDGFB
Platelet-derived growth factor subunit B

3

10

Small-scale

0.849

High

376373

PGFRA
Platelet-derived growth factor receptor alpha

6

20

Small-scale

0.735

High

376367

PDGFA
Platelet-derived growth factor subunit A

1

10

Small-scale

0.647

High

376383

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

2

Small-scale

0.647

High

287843

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

1

High-throughput

0.628

High

376390

FAT1
Protocadherin Fat 1

2

3

High-throughput

0.628

High

376398

FREM2
FRAS1-related extracellular matrix protein 2

2

6

High-throughput

0.628

High

376411

AGRV1
Adhesion G-protein coupled receptor V1

2

4

High-throughput

0.628

High

257706

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

2

0

High-throughput

0.602

High

376378

RL15
Large ribosomal subunit protein eL15

2

0

High-throughput

0.602

High

376379

RS15
Small ribosomal subunit protein uS19

2

0

High-throughput

0.602

High

376384

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

High-throughput

0.602

High

376386

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

High-throughput

0.602

High

376370

SPRC
SPARC

2

3

Small-scale

0.595

High

164212

NRP1
Neuropilin-1

2

7

Small-scale

0.584

High

376408

BRX1
Ribosome biogenesis protein BRX1 homolog

2

2

High-throughput

0.574

High

376409

FAT3
Protocadherin Fat 3

2

3

High-throughput

0.574

High

376410

NOC3L
Nucleolar complex protein 3 homolog

2

2

High-throughput

0.574

High

376424

NOC4L
Nucleolar complex protein 4 homolog

2

2

High-throughput

0.574

High

376418

MDFI
MyoD family inhibitor

1

1

High-throughput

0.560

High

376376

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.537

High

376363

CO1A1
Collagen alpha-1(I) chain

1

11

Small-scale

0.536

High

376364

CO2A1
Collagen alpha-1(II) chain

1

11

Small-scale

0.536

High

376365

CO3A1

1

11

Small-scale

0.536

High

376366

CO4A1

1

11

Small-scale

0.536

High

376369

CO1A2
Collagen alpha-2(I) chain

1

11

Small-scale

0.536

High

376372

CO6A1

1

9

Small-scale

0.536

High

376374

CO5A1

1

11

Small-scale

0.536

High

376401

DHX30
ATP-dependent RNA helicase DHX30

1

1

High-throughput

0.536

High

376426

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

1

High-throughput

0.536

High

376375

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

376412

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.513

High

376420

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

376368

TSP1
Thrombospondin-1

1

8

Small-scale

0.501

High

376387

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

2

Small-scale

0.501

High

376442

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

1

1

Small-scale

0.501

High

376399

FAT4
Protocadherin Fat 4

1

3

High-throughput

0.489

High

376440

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

193166

SOCS1
Suppressor of cytokine signaling 1

1

1

Small-scale

0.479

High

376394

ADIPO
Adiponectin

1

4

Small-scale

0.479

High

369564

A2MG
Alpha-2-macroglobulin

1

0

Small-scale

0.458

High

376388

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

1

Small-scale

0.445

High

75897

B4DEF8
Large ribosomal subunit protein mL45

1

1

High-throughput

0.437

High

376422

RM45
Large ribosomal subunit protein mL45

1

1

High-throughput

0.407

High

338027

NSA2
Ribosome biogenesis protein NSA2 homolog

2

0

High-throughput

0.328

High

376380

RT35
Small ribosomal subunit protein mS35

2

0

High-throughput

0.328

High

376381

RT05
Small ribosomal subunit protein uS5m

2

0

High-throughput

0.328

High

376382

RT09
Small ribosomal subunit protein uS9m

2

0

High-throughput

0.328

High

376385

CEBPZ
CCAAT/enhancer-binding protein zeta

2

0

High-throughput

0.328

High

376391

BMS1
Ribosome biogenesis protein BMS1 homolog

2

0

High-throughput

0.328

High

376392

PUM3
Pumilio homolog 3

2

0

High-throughput

0.328

High

376396

RM51
Large ribosomal subunit protein mL51

2

0

High-throughput

0.328

High

376403

SRRM1
Serine/arginine repetitive matrix protein 1

2

0

High-throughput

0.328

High

376406

RM30
Large ribosomal subunit protein uL30m

2

0

High-throughput

0.328

High

376407

DDX54
ATP-dependent RNA helicase DDX54

2

0

High-throughput

0.328

High

376413

RT31
Small ribosomal subunit protein mS31

2

0

High-throughput

0.328

High

376415

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

2

0

High-throughput

0.328

High

376416

RT24
Small ribosomal subunit protein uS3m

2

0

High-throughput

0.328

High

376417

PTCD3
Small ribosomal subunit protein mS39

2

0

High-throughput

0.328

High

376419

EBP2
Probable rRNA-processing protein EBP2

2

0

High-throughput

0.328

High

376427

RPF2
Ribosome production factor 2 homolog

2

0

High-throughput

0.328

High

376428

RM47
Large ribosomal subunit protein uL29m

2

0

High-throughput

0.328

High

376431

RBM28
RNA-binding protein 28

2

0

High-throughput

0.328

High

376432

TEX10
Testis-expressed protein 10

2

0

High-throughput

0.328

High

376433

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.328

High

376438

RT33
Small ribosomal subunit protein mS33

2

0

High-throughput

0.328

High

376439

RT18C
Small ribosomal subunit protein bS18m

2

0

High-throughput

0.328

High

376441

NOC2L
Nucleolar complex protein 2 homolog

2

0

High-throughput

0.328

High

376414

RL36L
Ribosomal protein eL42-like

2

0

High-throughput

0.318

High

376436

RL26L
Ribosomal protein uL24-like

2

0

High-throughput

0.318

High

376435

BCCIP
BRCA2 and CDKN1A-interacting protein

2

0

High-throughput

0.316

High

376377

RBM34
RNA-binding protein 34

1

0

High-throughput

0.279

Low

376389

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.279

Low

376393

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.279

Low

376395

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.279

Low

376397

RRP12
RRP12-like protein

1

0

High-throughput

0.279

Low

376400

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.279

Low

376402

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.279

Low

376404

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.279

Low

376405

KRI1
Protein KRI1 homolog

1

0

High-throughput

0.279

Low

376421

BUD13
BUD13 homolog

1

0

High-throughput

0.279

Low

376423

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

376425

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.279

Low

376429

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.279

Low

376430

SAS10
Something about silencing protein 10

1

0

High-throughput

0.279

Low

376434

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.279

Low

376437

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025