Protein: LAS1
Protein LAS1

Gene: LAS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P36146

Gene Ontology (top 5):
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000460 - maturation of 5.8S rRNA
GO:0000470 - maturation of LSU-rRNA
GO:0004519 - endonuclease activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733682

GRC3
Polynucleotide 5'-hydroxyl-kinase GRC3

10

2

Small-scale

0.976

High

733672

XRN2
5'-3' exoribonuclease 2

4

2

Small-scale

0.676

High

733668

DXO
Decapping nuclease RAI1

3

0

Small-scale

0.613

High

733652

LAS1
Protein LAS1

1

0

Small-scale

0.586

High

675967

XPO1
Exportin-1

1

1

High-throughput

0.536

High

689747

SFP1
Transcription factor SFP1

1

0

High-throughput

0.513

High

452989

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

593522

DBP3
ATP-dependent RNA helicase DBP3

1

1

Small-scale

0.479

High

604992

XRN1
5'-3' exoribonuclease 1

1

2

Small-scale

0.479

High

624067

DBP2
ATP-dependent RNA helicase DBP2

1

1

Small-scale

0.479

High

650275

SPT5
Transcription elongation factor SPT5

1

1

Small-scale

0.479

High

681314

TPS2
Trehalose-phosphatase

1

1

Small-scale

0.479

High

733654

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

Small-scale

0.479

High

733655

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

1

Small-scale

0.479

High

733661

ARB1
ABC transporter ATP-binding protein ARB1

1

2

Small-scale

0.479

High

733665

GSHR
Glutathione reductase

1

1

Small-scale

0.479

High

733673

NOG1
Nucleolar GTP-binding protein 1

1

1

Small-scale

0.479

High

733674

HAS1
ATP-dependent RNA helicase HAS1

1

1

Small-scale

0.479

High

733679

ERB1
Ribosome biogenesis protein ERB1

1

1

Small-scale

0.479

High

733683

NEW1
[NU+] prion formation protein 1

1

2

Small-scale

0.479

High

343187

TRP
Tryptophan synthase

1

0

Small-scale

0.458

High

389895

VDAC1
Mitochondrial outer membrane protein porin 1

1

0

Small-scale

0.458

High

404329

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

Small-scale

0.458

High

405167

RL17A
Large ribosomal subunit protein uL22A

1

0

Small-scale

0.458

High

410358

SC160
Protein SCP160

1

0

Small-scale

0.458

High

479724

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

481140

RL1A
Large ribosomal subunit protein uL1A

1

0

Small-scale

0.458

High

482854

RL35A
Large ribosomal subunit protein uL29A

1

0

Small-scale

0.458

High

485497

SSBP1
Single-stranded nucleic acid-binding protein

1

0

Small-scale

0.458

High

501356

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

Small-scale

0.458

High

534949

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.458

High

541684

SEC63
Protein translocation protein SEC63

1

0

Small-scale

0.458

High

564265

RL8A
Large ribosomal subunit protein eL8A

1

0

Small-scale

0.458

High

575943

ADT2
ADP,ATP carrier protein 2

1

0

Small-scale

0.458

High

596635

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

0

Small-scale

0.458

High

599453

VPS1
Vacuolar protein sorting-associated protein 1

1

0

Small-scale

0.458

High

602440

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

Small-scale

0.458

High

604539

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

Small-scale

0.458

High

627929

SIS1
Protein SIS1

1

0

Small-scale

0.458

High

631806

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.458

High

634128

SRO9
RNA-binding protein SRO9

1

0

Small-scale

0.458

High

644867

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.458

High

648363

NSR1
Nuclear localization sequence-binding protein

1

0

Small-scale

0.458

High

661941

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

689077

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

696302

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

Small-scale

0.458

High

699331

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

703588

PRS6A
26S proteasome regulatory subunit 6A

1

0

Small-scale

0.458

High

704317

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.458

High

733653

SYG
Glycine--tRNA ligase 1, mitochondrial

1

0

Small-scale

0.458

High

733656

SSF1
Ribosome biogenesis protein SSF1

1

0

Small-scale

0.458

High

733657

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

733658

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

Small-scale

0.458

High

733659

IF2P
Eukaryotic translation initiation factor 5B

1

0

Small-scale

0.458

High

733663

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

0

High-throughput

0.458

High

733664

NOP2
25S rRNA

1

0

Small-scale

0.458

High

733666

RS7B
Small ribosomal subunit protein eS7B

1

0

Small-scale

0.458

High

733667

ACS2
Acetyl-coenzyme A synthetase 2

1

0

Small-scale

0.458

High

733669

NSA1
Ribosome biogenesis protein NSA1

1

0

Small-scale

0.458

High

733671

YNE6
Uncharacterized endoplasmic reticulum membrane protein YNL046W

1

0

High-throughput

0.458

High

733675

ARX1
Probable metalloprotease ARX1

1

0

Small-scale

0.458

High

733680

RRP5
rRNA biogenesis protein RRP5

1

0

Small-scale

0.458

High

733681

YL271
Uncharacterized protein YLR271W

1

0

High-throughput

0.458

High

733684

MDN1
Midasin

1

0

Small-scale

0.458

High

733685

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

733686

RRP12
Ribosomal RNA-processing protein 12

1

0

Small-scale

0.458

High

490916

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493699

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

694496

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

733670

COPA
Coatomer subunit alpha

1

1

Small-scale

0.437

High

510946

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

733660

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

733678

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

358003

RS17A
Small ribosomal subunit protein eS17A

1

0

Small-scale

0.249

Low

425886

RS19A
Small ribosomal subunit protein eS19A

1

0

Small-scale

0.249

Low

479334

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.249

Low

481895

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.249

Low

546719

SEC23
Protein transport protein SEC23

1

0

Small-scale

0.249

Low

576138

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

630763

RHEB
Rheb-like protein RHB1

1

0

High-throughput

0.249

Low

733662

TMN3
Transmembrane 9 superfamily member 3

1

0

Small-scale

0.249

Low

733676

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

Small-scale

0.249

Low

733677

GPI19
Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024