Protein: IDUA
Alpha-L-iduronidase (EC 3.2.1.76)

Gene: IDUA
Organism: Homo sapiens
Interactions: 53
UniProt ID: P35475

Gene Ontology (top 5):
GO:0003940 - L-iduronidase activity
GO:0005102 - signaling receptor binding
GO:0005984 - disaccharide metabolic process
GO:0006027 - glycosaminoglycan catabolic process
GO:0030200 - heparan sulfate proteoglycan catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

771680

FBX6
F-box only protein 6

2

1

High-throughput

0.558

High

655983

CAH6
Carbonic anhydrase 6

1

1

High-throughput

0.536

High

85962

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

0

High-throughput

0.513

High

154800

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.513

High

449595

KLK1
Kallikrein-1

1

0

High-throughput

0.513

High

600599

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.513

High

647333

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.513

High

771655

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

771660

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

771662

FMOD
Fibromodulin

1

0

High-throughput

0.513

High

771673

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

771683

DNJB9
DnaJ homolog subfamily B member 9

1

0

High-throughput

0.513

High

771684

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.513

High

388501

CRP

1

1

High-throughput

0.489

High

771667

NPTX1
Neuronal pentraxin-1

1

1

High-throughput

0.489

High

771681

CAH10
Carbonic anhydrase-related protein 10

1

1

High-throughput

0.489

High

771682

CBLN4
Cerebellin-4

1

1

High-throughput

0.489

High

771685

FBX2
F-box only protein 2

1

1

High-throughput

0.489

High

222251

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

771663

SG2A2
Mammaglobin-A

2

0

High-throughput

0.328

High

65935

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

0

High-throughput

0.279

Low

73779

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

0

High-throughput

0.279

Low

168384

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.279

Low

298843

LYZL6
Lysozyme-like protein 6

1

0

High-throughput

0.279

Low

342518

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

426057

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.279

Low

485928

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.279

Low

506829

CFC1
Cryptic protein

1

0

High-throughput

0.279

Low

547977

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

593293

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.279

Low

771653

LEP
Leptin

1

0

High-throughput

0.279

Low

771654

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

771656

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

771658

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.279

Low

771659

IL5RA
Interleukin-5 receptor subunit alpha

1

0

High-throughput

0.279

Low

771665

PTC1
Protein patched homolog 1

1

0

High-throughput

0.279

Low

771666

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

771668

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

771670

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

771671

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

771672

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

771674

ESPB1
Epididymal sperm-binding protein 1

1

0

High-throughput

0.279

Low

771675

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

771676

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.279

Low

771677

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.279

Low

771678

CST11
Cystatin-11

1

0

High-throughput

0.279

Low

771679

LY9
T-lymphocyte surface antigen Ly-9

1

0

High-throughput

0.279

Low

157019

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

271943

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

771657

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

771661

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

771669

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

771664

MPP3
MAGUK p55 subfamily member 3

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025