Protein: GIP
Gastric inhibitory polypeptide (GIP) (Glucose-dependent insulinotropic polypeptide) (Incretin hormone)

Gene: GIP
Organism: Homo sapiens
Interactions: 46
UniProt ID: P09681

Gene Ontology (top 5):
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

485930

GIPR
Gastric inhibitory polypeptide receptor

1

0

Small-scale

0.696

High

239448

AGRB2
Adhesion G protein-coupled receptor B2

1

0

Small-scale

0.690

High

485935

COEA1
Collagen alpha-1(XIV) chain

2

1

High-throughput

0.628

High

226678

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

3

1

High-throughput

0.616

High

485949

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

485942

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.549

High

485943

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.549

High

485921

CALCB
Calcitonin gene-related peptide 2

1

2

High-throughput

0.536

High

485938

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

1

High-throughput

0.536

High

485951

COCA1

1

1

High-throughput

0.536

High

350675

NOE2
Noelin-2

1

0

High-throughput

0.513

High

485922

CO6A1

1

0

High-throughput

0.513

High

485923

CBPE
Carboxypeptidase E

1

0

High-throughput

0.513

High

485934

HBA
Hemoglobin subunit alpha

1

0

High-throughput

0.513

High

485937

PROL4
Proline-rich protein 4

1

0

High-throughput

0.513

High

485940

ARSK
Arylsulfatase K

1

0

High-throughput

0.513

High

485941

CREL2
Protein disulfide isomerase CRELD2

1

0

High-throughput

0.513

High

485952

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.513

High

485953

TOR3A
Torsin-3A

1

0

High-throughput

0.513

High

346598

TTC4
Tetratricopeptide repeat protein 4

1

2

High-throughput

0.489

High

485947

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.489

High

449644

CALCA
Calcitonin gene-related peptide 1

1

2

High-throughput

0.479

High

377247

CALC
Calcitonin [Cleaved into: Calcitonin

1

2

High-throughput

0.445

High

485926

DPP4
Dipeptidyl peptidase 4

1

1

Small-scale

0.445

High

485936

SEPR
Prolyl endopeptidase FAP

1

1

Small-scale

0.445

High

485924

CCNA2
Cyclin-A2

2

0

High-throughput

0.328

High

485954

RNF41
E3 ubiquitin-protein ligase NRDP1

2

0

High-throughput

0.328

High

183122

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

0

High-throughput

0.279

Low

228893

CF410
Cilia- and flagella-associated protein 410

1

0

High-throughput

0.279

Low

231437

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.279

Low

485925

KTHY
Thymidylate kinase

1

0

High-throughput

0.279

Low

485927

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.279

Low

485928

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

485929

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

0

High-throughput

0.279

Low

485931

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.279

Low

485939

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

485944

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

High-throughput

0.279

Low

485945

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low

485946

TM130
Transmembrane protein 130

1

0

High-throughput

0.279

Low

485948

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

485950

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.279

Low

485955

STK26
Serine/threonine-protein kinase 26

1

0

High-throughput

0.279

Low

485956

ADDG
Gamma-adducin

1

0

High-throughput

0.279

Low

485957

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.279

Low

485932

DLX6
Homeobox protein DLX-6

1

0

High-throughput

0.269

Low

485933

KR103
Keratin-associated protein 10-3

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025