Protein: RN5A
2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L)

Gene: RN5A, RNASEL
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q05823

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004521 - RNA endonuclease activity
GO:0004540 - RNA nuclease activity
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1052378

DOCK5
Dedicator of cytokinesis protein 5

2

4

High-throughput

0.811

High

1052382

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

6

16

High-throughput

0.737

High

1052376

LPAR4
Lysophosphatidic acid receptor 4

2

2

High-throughput

0.726

High

1052362

RN5A
2-5A-dependent ribonuclease

1

17

Small-scale

0.692

High

74470

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.691

High

413683

P53
Cellular tumor antigen p53

1

5

High-throughput

0.691

High

959139

ABCE1
ATP-binding cassette sub-family E member 1

1

4

Small-scale

0.647

High

187068

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.618

High

1052373

PXDN
Peroxidasin homolog

1

3

High-throughput

0.618

High

289142

PRDM1
PR domain zinc finger protein 1

1

1

Small-scale

0.618

High

1052368

ANR11
Ankyrin repeat domain-containing protein 11

1

17

High-throughput

0.618

High

231560

PRKY
Putative serine/threonine-protein kinase PRKY

1

8

High-throughput

0.575

High

1035554

KIF23
Kinesin-like protein KIF23

1

8

Small-scale

0.575

High

1052365

I13R2
Interleukin-13 receptor subunit alpha-2

2

6

High-throughput

0.574

High

66002

U119B
Protein unc-119 homolog B

1

2

High-throughput

0.536

High

569451

DHB1
17-beta-hydroxysteroid dehydrogenase type 1

1

2

High-throughput

0.536

High

935851

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

4

High-throughput

0.536

High

1052364

TCOF
Treacle protein

1

15

High-throughput

0.536

High

1052379

SPCS
O-phosphoseryl-tRNA(Sec) selenium transferase

1

0

High-throughput

0.513

High

862816

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

10

Small-scale

0.500

High

130077

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.489

High

229699

CALU
Calumenin

1

6

High-throughput

0.489

High

388621

C1QA
Complement C1q subcomponent subunit A

1

1

High-throughput

0.489

High

706106

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

774309

BASI
Basigin

1

6

High-throughput

0.489

High

1052363

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.489

High

1052369

SV2A
Synaptic vesicle glycoprotein 2A

1

5

High-throughput

0.489

High

1052371

SPX3
Sugar phosphate exchanger 3

1

1

High-throughput

0.489

High

1052375

HTF4
Transcription factor 12

1

1

High-throughput

0.481

High

293598

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

1052366

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.445

High

1010908

BAT1
b(0,+)-type amino acid transporter 1

1

6

High-throughput

0.407

High

1052367

S35E4
Solute carrier family 35 member E4

1

2

High-throughput

0.407

High

1052374

S67A1
Solute carrier family 67 member A1

1

6

High-throughput

0.407

High

1052377

S39A3
Zinc transporter ZIP3

1

2

High-throughput

0.407

High

1052380

S22AB
Solute carrier family 22 member 11

1

3

High-throughput

0.407

High

1052381

S39A9
Zinc transporter ZIP9

1

2

High-throughput

0.407

High

1052384

XCT
Cystine/glutamate transporter

1

6

High-throughput

0.407

High

469477

SYPH
Synaptophysin

2

0

High-throughput

0.328

High

1052372

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

0

High-throughput

0.328

High

854527

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.279

Low

880131

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

946303

NXPH1
Neurexophilin-1

1

0

High-throughput

0.279

Low

1052370

PRS42
Putative serine protease 42

1

0

High-throughput

0.279

Low

1052383

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.279

Low

1052385

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025