Protein: SPX3
Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)

Gene: SPX3, SLC37A3
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q8NCC5

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0006855 - xenobiotic transmembrane transport
GO:0042910 - xenobiotic transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1248320

ARAID
All-trans retinoic acid-induced differentiation factor

3

0

High-throughput

0.634

High

1335439

DAAM1
Disheveled-associated activator of morphogenesis 1

3

1

High-throughput

0.604

High

403203

APOB
Apolipoprotein B-100

2

0

High-throughput

0.602

High

1041179

CAV1
Caveolin-1

2

0

High-throughput

0.602

High

942501

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

2

2

High-throughput

0.601

High

360043

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.576

High

931268

AT12A
Potassium-transporting ATPase alpha chain 2

2

2

High-throughput

0.574

High

1335434

ARL15
ADP-ribosylation factor-like protein 15

2

2

High-throughput

0.574

High

1335440

KC1G3
Casein kinase I isoform gamma-3

2

1

High-throughput

0.574

High

374069

RASN
GTPase NRas

1

2

High-throughput

0.536

High

1052371

RN5A
2-5A-dependent ribonuclease

1

1

High-throughput

0.489

High

844216

ECE1
Endothelin-converting enzyme 1

1

4

High-throughput

0.445

High

1335431

AT131
Endoplasmic reticulum transmembrane helix translocase

1

4

High-throughput

0.445

High

1335436

NOTC3
Neurogenic locus notch homolog protein 3

1

4

High-throughput

0.445

High

519642

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.426

High

1159158

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.426

High

175397

PLXB2
Plexin-B2

1

2

High-throughput

0.407

High

214316

MSI1H
RNA-binding protein Musashi homolog 1

1

1

High-throughput

0.407

High

877357

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

High-throughput

0.407

High

895268

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

1

High-throughput

0.407

High

895607

SERPH
Serpin H1

1

4

High-throughput

0.407

High

993435

ACTH
Actin, gamma-enteric smooth muscle

1

2

High-throughput

0.407

High

997040

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.407

High

1241095

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

4

High-throughput

0.407

High

1259358

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.407

High

1275441

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

1

High-throughput

0.407

High

1295173

AN13B
Ankyrin repeat domain-containing protein 13B

1

3

High-throughput

0.407

High

1316745

WDFY3
WD repeat and FYVE domain-containing protein 3

1

1

High-throughput

0.407

High

1335420

PDC6I
Programmed cell death 6-interacting protein

1

4

High-throughput

0.407

High

1335426

VAT1
Synaptic vesicle membrane protein VAT-1 homolog

1

2

High-throughput

0.407

High

1335424

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

3

0

High-throughput

0.345

High

665114

COT2
COUP transcription factor 2

2

0

High-throughput

0.328

High

922469

CLH2
Clathrin heavy chain 2

2

0

High-throughput

0.328

High

1204930

MTX3
Metaxin-3

2

0

High-throughput

0.328

High

1210698

KMCP1
Kidney mitochondrial carrier protein 1

2

0

High-throughput

0.328

High

1219982

SPRY7
SPRY domain-containing protein 7

2

0

High-throughput

0.328

High

1335423

S2546
Mitochondrial outer membrane protein SLC25A46

2

0

High-throughput

0.328

High

1335428

GCP2
Gamma-tubulin complex component 2

2

0

High-throughput

0.328

High

923426

SC5A3
Sodium/myo-inositol cotransporter

2

0

High-throughput

0.288

High

1103084

ZN177
Zinc finger protein 177

1

0

High-throughput

0.282

High

1335422

FOXJ1
Forkhead box protein J1

1

0

High-throughput

0.282

High

1335430

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

288243

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

0

High-throughput

0.232

Low

321774

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.232

Low

467842

BGLR
Beta-glucuronidase

1

0

High-throughput

0.232

Low

870988

AT5G3
ATP synthase F(0) complex subunit C3, mitochondrial

1

0

High-throughput

0.232

Low

914102

HXK2
Hexokinase-2

1

0

High-throughput

0.232

Low

941937

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.232

Low

1153474

EFNB3
Ephrin-B3

1

0

High-throughput

0.232

Low

1216462

TMCO4
Transmembrane and coiled-coil domain-containing protein 4

1

0

High-throughput

0.232

Low

1245535

OGFD3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

1

0

High-throughput

0.232

Low

1277502

MON2
Protein MON2 homolog

1

0

High-throughput

0.232

Low

1280656

PKHH3
Pleckstrin homology domain-containing family H member 3

1

0

High-throughput

0.232

Low

1335419

TM263
Transmembrane protein 263

1

0

High-throughput

0.232

Low

1335421

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.232

Low

1335425

RUSF1
RUS family member 1

1

0

High-throughput

0.232

Low

1335427

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.232

Low

1335429

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

1335432

INO1
Inositol-3-phosphate synthase 1

1

0

High-throughput

0.232

Low

1335433

C42S2
CDC42 small effector protein 2

1

0

High-throughput

0.232

Low

1335435

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.232

Low

1335437

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.232

Low

1335438

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025