Protein: GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]

Gene: GLCNE, GNE
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q9Y223

Gene Ontology (top 5):
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006045 - N-acetylglucosamine biosynthetic process
GO:0006047 - UDP-N-acetylglucosamine metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490440

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

1

3

High-throughput

0.698

High

685977

KRA59
Keratin-associated protein 5-9

3

15

High-throughput

0.675

High

950438

KR107
Keratin-associated protein 10-7

3

13

High-throughput

0.675

High

950727

KR108
Keratin-associated protein 10-8

3

13

High-throughput

0.675

High

1146215

K1H1
Keratin, type I cuticular Ha1

3

5

High-throughput

0.675

High

1419042

KRA92
Keratin-associated protein 9-2

3

14

High-throughput

0.675

High

1277447

NT2NA
Notch homolog 2 N-terminal-like protein A

3

1

High-throughput

0.609

High

221402

SPY1
Protein sprouty homolog 1

2

2

High-throughput

0.606

High

221433

SPY3
Protein sprouty homolog 3

2

2

High-throughput

0.606

High

227262

KRT86
Keratin, type II cuticular Hb6

2

2

High-throughput

0.606

High

300530

KRT34
Keratin, type I cuticular Ha4

2

5

High-throughput

0.606

High

1007507

KRT83
Keratin, type II cuticular Hb3

2

2

High-throughput

0.606

High

1007552

KRT85
Keratin, type II cuticular Hb5

2

2

High-throughput

0.606

High

1059762

KRA11
Keratin-associated protein 1-1

2

13

High-throughput

0.606

High

1187763

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.606

High

1198057

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.606

High

1230315

K1C40
Keratin, type I cytoskeletal 40

2

5

High-throughput

0.606

High

1307474

KRA13
Keratin-associated protein 1-3

2

13

High-throughput

0.606

High

1418991

KRA98
Keratin-associated protein 9-8

2

14

High-throughput

0.606

High

1419023

KRA93
Keratin-associated protein 9-3

2

14

High-throughput

0.606

High

1419063

KR411
Keratin-associated protein 4-11

2

15

High-throughput

0.606

High

1419067

KRA41
Keratin-associated protein 4-1

2

14

High-throughput

0.606

High

1419088

KRA44
Keratin-associated protein 4-4

2

15

High-throughput

0.606

High

1419118

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.606

High

1419143

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.606

High

1063898

LG3BP
Galectin-3-binding protein

3

1

High-throughput

0.604

High

572285

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

949635

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.580

High

1151687

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.580

High

1186543

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.580

High

1186614

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.580

High

1186725

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1187938

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.580

High

1307073

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

1418976

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.580

High

1453179

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

221198

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.573

High

950921

KR109
Keratin-associated protein 10-9

1

14

High-throughput

0.573

High

1410119

KR412
Keratin-associated protein 4-12

1

15

High-throughput

0.573

High

555788

ACTN1
Alpha-actinin-1

1

0

Small-scale

0.561

High

699477

PROP
Properdin

2

1

High-throughput

0.553

High

885452

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.553

High

1311484

TRI42
Tripartite motif-containing protein 42

2

2

High-throughput

0.553

High

1412053

WDR83
WD repeat domain-containing protein 83

2

1

High-throughput

0.553

High

1459918

EGFL7
Epidermal growth factor-like protein 7

2

2

High-throughput

0.553

High

950141

KR105
Keratin-associated protein 10-5

1

14

High-throughput

0.515

High

302099

SEGN
Secretagogin

1

0

High-throughput

0.513

High

1449450

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1186815

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

1025235

HXC5
Homeobox protein Hox-C5

1

1

High-throughput

0.489

High

950036

KR103
Keratin-associated protein 10-3

1

14

High-throughput

0.481

High

517138

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1308339

Q8IV28
Nidogen-2

1

1

High-throughput

0.470

High

401715

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

412827

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

935309

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

942964

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1050573

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

1067851

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1114681

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1380260

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1459342

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1120559

NID2
Nidogen-2

1

1

High-throughput

0.439

High

1356096

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

1

High-throughput

0.439

High

1256138

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

451093

LDHB
L-lactate dehydrogenase B chain

1

0

Small-scale

0.426

High

1250336

ATL4
ADAMTS-like protein 4

3

0

High-throughput

0.352

High

1179271

CB068
UPF0561 protein C2orf68

3

0

High-throughput

0.347

High

705612

GRN
Progranulin

3

0

High-throughput

0.344

High

1392757

ZN764
Zinc finger protein 764

2

0

High-throughput

0.328

High

70536

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

165201

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

192143

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

1159435

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.316

High

1180134

VWC2
Brorin

2

0

High-throughput

0.316

High

1213860

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1243001

CV039
Synaptic plasticity regulator PANTS

2

0

High-throughput

0.316

High

1407137

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1381653

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

1

0

High-throughput

0.299

High

163520

ZN213
Zinc finger protein 213

1

0

High-throughput

0.279

Low

1192145

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.279

Low

1340878

GA2L2
GAS2-like protein 2

1

0

High-throughput

0.279

Low

301766

WFS1
Wolframin

1

0

High-throughput

0.268

Low

658

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

1180437

PRIC4
Prickle-like protein 4

1

0

High-throughput

0.251

Low

1191411

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

373524

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

418520

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

590056

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696889

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769538

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1276983

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1332918

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1368215

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

1434257

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1366312

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025