Protein: SMUG1
Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-)

Gene: SMUG1
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q53HV7

Gene Ontology (top 5):
GO:0000703 - oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0001650 - fibrillar center
GO:0003677 - DNA binding
GO:0004844 - uracil DNA N-glycosylase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1200174

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

2

0

High-throughput

0.742

High

1065944

VAC14
Protein VAC14 homolog

4

0

High-throughput

0.675

High

1200186

RBPMS
RNA-binding protein with multiple splicing

3

0

High-throughput

0.649

High

1186941

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.606

High

1198012

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.606

High

681825

RBTN2
Rhombotin-2

2

0

High-throughput

0.589

High

225598

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

295982

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.580

High

330184

VENTX
Homeobox protein VENTX

2

0

High-throughput

0.580

High

912911

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

0

High-throughput

0.580

High

1081378

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1098559

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.580

High

1156016

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.580

High

1186625

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1200178

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.580

High

1200181

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.580

High

1200182

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.580

High

1200183

GLCTK
Glycerate kinase

2

0

High-throughput

0.580

High

1200185

TFG
Protein TFG

2

0

High-throughput

0.580

High

1200189

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.580

High

1200192

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

1200194

NEK6
Serine/threonine-protein kinase Nek6

2

0

High-throughput

0.580

High

1200195

TF7L2
Transcription factor 7-like 2

2

0

High-throughput

0.580

High

1200196

PRR13
Proline-rich protein 13

2

0

High-throughput

0.580

High

277102

PROP1
Homeobox protein prophet of Pit-1

2

1

High-throughput

0.553

High

555495

SKIL
Ski-like protein

1

0

High-throughput

0.518

High

1200199

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.518

High

1200176

ZN318
Zinc finger protein 318

1

0

High-throughput

0.513

High

210012

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.494

High

1028996

TIAR
Nucleolysin TIAR

1

0

High-throughput

0.493

High

1146373

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.493

High

1200180

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.493

High

1200184

F222B
Protein FAM222B

1

0

High-throughput

0.493

High

1200187

OPTN
Optineurin

1

0

High-throughput

0.493

High

1200191

PITX2
Pituitary homeobox 2

1

0

High-throughput

0.493

High

1200193

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

0

High-throughput

0.493

High

959485

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.460

High

422248

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.458

High

1200198

XPO7
Exportin-7

1

1

High-throughput

0.437

High

70245

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

506735

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1200175

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1200179

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.316

High

1200188

KLD7B
Kelch domain-containing protein 7B

2

0

High-throughput

0.316

High

1200190

TEKT5
Tektin-5

2

0

High-throughput

0.316

High

1200197

PEF1
Peflin

2

0

High-throughput

0.316

High

1150981

PCH2
Pachytene checkpoint protein 2 homolog

1

0

High-throughput

0.282

High

1200200

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

0

High-throughput

0.279

Low

1200177

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.269

Low

1191361

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025