Protein: CO2A1
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]

Gene: CO2A1, COL2A1
Organism: Homo sapiens
Interactions: 53
UniProt ID: P02458

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001502 - cartilage condensation
GO:0001894 - tissue homeostasis
GO:0001958 - endochondral ossification
GO:0002062 - chondrocyte differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

358596

CO9A1

4

17

Small-scale

0.899

High

358590

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

3

20

High-throughput

0.861

High

358618

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

20

High-throughput

0.861

High

358599

CO8A2
Collagen alpha-2(VIII) chain

3

19

High-throughput

0.847

High

70495

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

20

High-throughput

0.691

High

358582

C1QC
Complement C1q subcomponent subunit C

1

20

High-throughput

0.691

High

358600

CO8A1
Collagen alpha-1(VIII) chain

1

19

High-throughput

0.691

High

358617

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

20

High-throughput

0.691

High

358586

TSP1
Thrombospondin-1

1

9

Small-scale

0.647

High

358587

MMP2
72 kDa type IV collagenase

2

20

High-throughput

0.628

High

358595

MMP9
Matrix metalloproteinase-9

2

20

High-throughput

0.628

High

358613

GT252
Procollagen galactosyltransferase 2

2

20

High-throughput

0.628

High

358581

CO2A1
Collagen alpha-1(II) chain

1

16

High-throughput

0.618

High

358440

CO1A1
Collagen alpha-1(I) chain

1

18

Small-scale

0.575

High

358610

Q4VAQ0
COL8A2 protein

1

20

High-throughput

0.575

High

311308

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

2

4

High-throughput

0.574

High

358621

CNPY2
Protein canopy homolog 2

2

1

High-throughput

0.574

High

358604

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

20

High-throughput

0.567

High

358592

BMP2
Bone morphogenetic protein 2

1

7

Small-scale

0.561

High

358608

KEAP1
Kelch-like ECH-associated protein 1

2

4

High-throughput

0.553

High

350941

PDGFB
Platelet-derived growth factor subunit B

1

11

Small-scale

0.536

High

358594

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

5

High-throughput

0.536

High

358611

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

12

High-throughput

0.536

High

358614

OSCAR
Osteoclast-associated immunoglobulin-like receptor

1

12

High-throughput

0.536

High

358605

TF65
Transcription factor p65

1

0

High-throughput

0.518

High

358606

HYAL1
Hyaluronidase-1

1

0

High-throughput

0.518

High

305206

NXPH2
Neurexophilin-2

1

0

High-throughput

0.513

High

203013

COCH
Cochlin

1

13

Small-scale

0.501

High

351208

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

7

Small-scale

0.501

High

358584

PDGFA
Platelet-derived growth factor subunit A

1

11

Small-scale

0.501

High

358588

ITA2B
Integrin alpha-IIb

1

5

Small-scale

0.501

High

358589

ANXA5
Annexin A5

1

4

Small-scale

0.501

High

358597

MAG
Myelin-associated glycoprotein

1

5

Small-scale

0.501

High

358601

PRELP
Prolargin

1

3

Small-scale

0.501

High

358603

PKD1
Polycystin-1

1

1

Small-scale

0.501

High

358607

PDIA2
Protein disulfide-isomerase A2

1

7

Small-scale

0.501

High

124357

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.493

High

358585

GELS
Gelsolin

1

0

High-throughput

0.493

High

358593

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

358598

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.493

High

329215

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.479

High

358583

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

358591

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

358620

UBQL1
Ubiquilin-1

1

3

High-throughput

0.470

High

358612

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

Small-scale

0.437

High

358619

CHODL
Chondrolectin

1

0

High-throughput

0.279

Low

263467

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.268

Low

358602

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

358609

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

358615

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.268

Low

358622

Q9Y649
GW128

1

0

High-throughput

0.268

Low

358616

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024