Protein: NELFD
Negative elongation factor C/D (NELF-C/D) (TH1-like protein)

Gene: NELFD, NELFCD
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q8IXH7

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016020 - membrane
GO:0032021 - NELF complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1312156

NELFB
Negative elongation factor B

8

1

Small-scale

0.972

High

1312170

NELFA
Negative elongation factor A

11

1

Small-scale

0.761

High

615567

NELFE
Negative elongation factor E

10

1

Small-scale

0.758

High

1050472

UBE3A
Ubiquitin-protein ligase E3A

2

1

Small-scale

0.636

High

260159

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

520193

ANDR
Androgen receptor

1

2

Small-scale

0.561

High

1102592

MTA1
Metastasis-associated protein MTA1

1

1

High-throughput

0.541

High

966589

1433G
14-3-3 protein gamma

1

2

High-throughput

0.536

High

990470

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.536

High

1061047

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.536

High

1099426

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.536

High

460589

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.518

High

727879

DNJA1
DnaJ homolog subfamily A member 1

1

0

High-throughput

0.518

High

948446

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.518

High

1016348

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.518

High

1312164

HDA11
Histone deacetylase 11

1

0

High-throughput

0.518

High

130531

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

596213

H12
Histone H1.2

1

0

High-throughput

0.513

High

621684

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.513

High

621910

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

723015

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

807953

SMBP2
DNA-binding protein SMUBP-2

1

0

High-throughput

0.513

High

923511

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

934239

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

994289

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

1030477

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.513

High

1066709

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

1091314

FOXL1
Forkhead box protein L1

1

0

High-throughput

0.513

High

1310209

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1312159

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.513

High

1312160

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

0

High-throughput

0.513

High

1312166

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

185838

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

167315

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

1279617

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1049535

1433F
14-3-3 protein eta

1

2

High-throughput

0.489

High

139722

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.486

High

162623

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.486

High

1106599

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.486

High

731448

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

958988

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.479

High

1201946

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

1312158

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1312174

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

46369

A0A1U9X8X8
Corneodesmosin

1

1

High-throughput

0.470

High

1134001

ZN638
Zinc finger protein 638

1

0

High-throughput

0.460

High

132150

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

246743

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

278889

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

360444

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

420605

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

560008

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

646883

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

697169

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

756261

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.458

High

972479

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

973495

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

983171

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.458

High

1047045

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

High-throughput

0.458

High

1107898

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1214521

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1312152

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

1312154

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1312161

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1312165

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

1312169

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1312171

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

1312172

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1312173

ANC2
Anaphase-promoting complex subunit 2

1

0

High-throughput

0.458

High

1312175

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1312176

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.458

High

1149518

CDSN
Corneodesmosin

1

1

High-throughput

0.439

High

1280066

FRMD5
FERM domain-containing protein 5

1

0

High-throughput

0.438

High

397967

ANGI
Angiogenin

1

0

High-throughput

0.426

High

911635

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.426

High

954714

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

1111094

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

521389

ARAF
Serine/threonine-protein kinase A-Raf

3

0

Small-scale

0.351

High

653428

HEMH
Ferrochelatase, mitochondrial

3

0

High-throughput

0.345

High

1040477

GSTM4
Glutathione S-transferase Mu 4

1

0

High-throughput

0.282

High

185011

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.279

Low

474806

VIME
Vimentin

1

0

High-throughput

0.279

Low

762243

TRY3
Trypsin-3

1

0

High-throughput

0.279

Low

996756

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.279

Low

1294665

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

1312155

NETO2
Neuropilin and tolloid-like protein 2

1

0

High-throughput

0.279

Low

469306

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.269

Low

1312168

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

124400

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

412227

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

485875

COX6C
Cytochrome c oxidase subunit 6C

1

0

High-throughput

0.249

Low

519156

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

528478

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.249

Low

576117

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.249

Low

634129

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

773556

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.249

Low

1233330

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1254551

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1256917

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1293610

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1312162

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

1312163

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.249

Low

1116761

AAMP
Angio-associated migratory cell protein

1

0

High-throughput

0.238

Low

1312153

ENDOV
Endonuclease V

1

0

High-throughput

0.238

Low

1312167

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.238

Low

337179

APOM
Apolipoprotein M

1

0

High-throughput

0.232

Low

1312157

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025